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Molecular basis of inheritance

Total questions: 15

Worksheet time: 5mins

Name
Class
Date
1.

In a DNA strand the nucleotides are linked together by

a)

glycosidic bonds


b)

phosphodiester bonds

c)

peptide bonds

d)

hydorgen bonds.

2.

The electric charge on DNA and histones is

a)

both positive

b)

both negative

c)

zero

d)

negative and positive respectively

3.

The human chromosome with the highest and least number of genes in them are respectively

a)

chromosome 21 and Y

b)

chromosome 1 and X

c)

chromosome 1 and Y

d)

chromosome X and Y.

4.

In prokaryotes, control of gene expression takes place at the level of

a)

transcription

b)

translation

c)

DNA replication

d)

All of the above

5.

Which was the last human chromosome to be completely sequenced ?

a)

Chromosome X

b)

Chromosome 21

c)

Chromosome 1

d)

Chromosome Y

6.

If the sequence of nitrogen bases of the coding strand of DNA in a transcription unit is: 5’ – ATGAATG – 3’, the sequence of bases in its RNA transcript would be

a)

5’ – AUG A AUG – 3’

b)

5’ – UACUU AC – 3’

c)

5’ – CAUUCAU – 3’

d)

5’ – GUAAGUA – 3’.

7.

If the base sequence of a codon in mRNA is 5’ – AUG – 3′ the sequence of tRNA pairing with it must be

a)

5’ – UAC – 3’

b)

5’ – CAU – 3’

c)

5’-AUG – 3’

d)

5’ – GUA – 3’

8.

In E. coli, the lac operon gets switched on when

a)

lactose is present and it binds to the repressor

b)

repressor binds to operator

c)

RNA polymerase binds to the operator

d)

lactose is present and it binds to RNA polymerase

9.

If a double stranded DNA has 20% of cytosine, what will be the percentage of adenine in it ?

a)

20%

b)

30%

c)

40%

d)

60%

10.

How far is each base pair from the next one in DNA double helix model ?

a)

2 nm


b)

3.4 nm

c)

34 nm

d)

0.34 nm

11.

The structure in chromatin seen as ‘beads-on string’ when viewed under electron microscope are called

a)

chromosomes

b)

nucleotides

c)

nucleosomes

d)

histone octamer

12.

Find out the wrong statement about heterochromatin

a)

It is densely packed

b)

It stains dark.

c)

It is transcriptionally active.

d)

It is late replicating.

13.

Which out of the following statements is incorrect ?

a)

Genetic code is ambiguous.

b)

Genetic code is degenerate

c)

Genetic code is universal.

d)

genetic code is punctuation-free

14.

During translation, activated amino acids get linked to tRNA. This process is commonly called as

a)

charging of tRNA

b)

discharging of tRNA

c)

aminoacylation of tRNA

d)

Both A&C

15.

Select the correct match of enzyme with its related function

a)

DNA polymerase – Synthesis of DNA strands


b)

Helicase – Unwinding of DNA helix

c)

Ligase – Joins together short DNA segments

d)

All of these