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WorksheetsModule 4 Part 2: Hematology
Total questions: 14
Worksheet time: 7mins
A patient takes longer than average to stop bleeding after a blood draw. The patient has the following labs.
PT = Normal
aPTT = High
BT = High
PLT = Normal
What is the diagnosis?
A patient has a high PT, high aPTT, high BT, and low PLT. What is the most likely diagnosis?
Hemophilia A
Von Willebrand Disease
Thrombocytopenia
Disseminated Intravascular Coagulation
A patient has a high aPTT, but normal PT, BT, and PLT. What is the most likely diagnosis?
Hemophilia A
Von Willebrand Disease
Thrombocytopenia
Disseminated Intravascular Coagulation
aPTT is elevated in von Willebrand's Disease ___ of the time
25%
50%
75%
100%
Liver disease would cause elevations in
PT only
aPTT only
PT and aPTT
PT, aPTT, BT
Hypocalcemia would affect
Intrinsic pathway only
Extrinsic pathway only
Common pathway only
All three pathways
John Doe, a 28-year-old male engineer, presented to the Hematology Clinic with a history of recurrent episodes of uncontrolled bleeding. He reported multiple instances of prolonged bleeding following minor injuries, dental extractions, and spontaneous nosebleeds since childhood. His family history was significant for a maternal uncle who had similar bleeding tendencies. John sought medical attention due to increasing concerns about the frequency and severity of his bleeding episodes. John's family history revealed a strong predisposition to bleeding disorders. His maternal uncle had a confirmed diagnosis of hemophilia B, and there were anecdotal reports of other male relatives experiencing excessive bleeding after minor injuries. How would you treat John's condition?
Administer clotting factor VIII
Hemophilia A is treated with ___ and Hemophilia B is treated with ___
Tissue Plasminogen Activator (tPA) initiates the conversion of ___ to ___
D-dimer test can be used for which of the following conditions?
DIC
DVT
PE
Stroke
Hemophiliacs bleed faster. True or false?
A patient presents with a prolonged bleeding time, normal PT, and normal aPTT. Platelet count is also normal. What could be the possible diagnosis?
Hemophilia A
Von Willebrand Disease
Thrombocytopenia
Disseminated Intravascular Coagulation
Mary Smith, a 45-year-old schoolteacher, presented to the Hematology Clinic with a history of easy bruising, nosebleeds, and gum bleeding for the past two months. She reported multiple episodes of spontaneous nosebleeds, even with minimal trauma or no apparent cause. Additionally, she noticed that her gums bled when she brushed her teeth, and she had a series of unexplained bruises on her arms and legs. Concerned about these symptoms, she decided to seek medical attention. Complete Blood Count (CBC) reveals the following:
Hemoglobin: 12.8 g/dL (Reference Range: 12.0-15.5 g/dL)
Platelet count: 32,000/mm³ (Reference Range: 150,000-450,000/mm³)
Prothrombin Time (PT): Normal
Activated Partial Thromboplastin Time (aPTT): Normal
What is Mary's diagnosis?
Hemophilia A
Hemophilia B
Von Willebrand's disease
All of the following is true about Disseminated Intravascular Coagulation EXCEPT:
Clotting factors and platelets increase in number
Tissue factor (TF) is released and triggers the coagulation pathway
Clots trap platelets and increase clot production, resulting in end-organ damage
Further hemorrhage takes place due to platelets and clotting factor consuption
