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WorksheetsGenetic Factors in Schizophrenia A01
Total questions: 14
Worksheet time: 7mins
What is the estimated heritability of schizophrenia?
39%
59%
79%
99%
How many genes have been linked to schizophrenia?
100
300
700
1,000
What can cause spontaneous changes in the DNA code?
Environmental factors
Cell division errors
Both A and B
None of the above
Which syndrome is caused by the deletion of genes on chromosome 22?
Down Syndrome
Turner Syndrome
DiGeorge Syndrome
Klinefelter Syndrome
Which gene is linked to the presence of schizophrenia in DiGeorge Syndrome?
COMT gene
DISC1 gene
GABA gene
Glutamate gene
People with an abnormality in which gene are more likely to develop schizophrenia?
COMT gene
DISC1 gene
GABA gene
Glutamate gene
What does the DISC1 gene code for?
Dopamine
GABA
Glutamate
Serotonin
Do genes cause schizophrenia or create a vulnerability for it?
Genes cause schizophrenia
Genes create a vulnerability
Both A and B
None of the above
What is considered as 'stress' in the diathesis-stress model of schizophrenia?
Psychological factors
Harsh parenting
Cannabis use
All of the above
What is the risk of developing schizophrenia due to cannabis use?
1.5 times
3 times
5 times
7 times
How does cannabis use affect the dopamine system?
Increases dopamine levels
Decreases dopamine levels
Alters dopamine regulation
Has no effect on dopamine
What is the role of the COMT gene in the prefrontal cortex?
Breaks down dopamine
Creates GABA
Regulates glutamate
Produces serotonin
Which neurotransmitter does GABA regulate in the limbic system?
Dopamine
Glutamate
Serotonin
Norepinephrine
What is the main risk factor for triggering an episode of schizophrenia?
Genetic factors
Environmental factors
Psychological factors
Cannabis use
