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Quiz-3

Total questions: 20

Worksheet time: 12mins

Name
Class
Date
1.

Specialized proteins which transport lipid in body are known as

a)

Globulin

b)

Albumin

c)

Apoprotein

d)

None of these

2.

State True or False- Primary dyslipidemia is due to illness or metabolic disturbances, e.g., diabetes mellitus.

a)

True

b)

False

3.

Choose Correct sequence of Endogenous pathway

a)

IDL-LDL-VLDL-LDL Remnants

b)

VLDL-IDL-LDL-LDL Remnants

c)

LDL Remnants-LDL-IDL-VLDL

d)

None of these

4.

In Hypercholesterolemia, specifically ____is raised and found in higher concentration in blood.

a)

Triglycerides

b)

LDL

c)

Phospholipids

d)

None of these

5.

Diabetic dyslipidemia is characterized by High TG, Low HDL and high _______.

a)

LDL

b)

Phospholipid

c)

small dense LDL

d)

None of these

6.

As per NCEP ATP III guidelines, optimal level of LDL is _____mg/dl

a)

>190 mg/dl

b)

>160 mg/dl

c)

>100 mg/dl

d)

<100 mg/dl

7.

As per NCEP ATP III guidelines, desirable level of TG is _____mg/dl

a)

<200

b)

>200

c)

>250

d)

>300

8.

Statin inhibit _________ enzyme and inhibit cholesterol synthesis

a)

HMGCoA Synthase

b)

HMGCoA Reductase

c)

Mevalonate

d)

Geranyl

9.

Pleotropic benefits of statins include

a)

Increased plaque stability

b)

Decreased vascular inflammation

c)

Improved endothelial function

d)

All of these

10.

Half life of atorvastatin is ______hours

a)

10 hours

b)

8 hours

c)

14 to 17 hours

d)

11 to 13 hours

11.

Aspirin selectively inhibits _______ formation and reduces platelet aggregation and intravascular thrombosis.

a)

ADP

b)

VWF

c)

Thromboxane A2

d)

None of these

12.

Clopidogrel inhibits the _______ receptor on the platelets and thereby inhibits platelet aggregation.

a)

Cox 1

b)

Cox 2

c)

ADP

d)

None of these

13.

Fenofibrate is a _________agonist which reduces triglycerides by increasing Lipoprotein Lipase enzyme synthesis and action.

a)

PPAR alpha

b)

PPAR Beta

c)

PPAR Gama

d)

PPAR Delta

14.

Recommended starting dose of Stator in dyslipidemia is ____mg OD which can be up titrated to ___mg OD with or without food at any time of the day.

a)

10, 20

b)

20, 40

c)

10, 80

d)

None of these

15.

Amongst 3 pathways of Lipid transport, Reverse cholesterol transport is associated with

a)

Distribution of TG to cells

b)

Removal of excess cholesterol from cell by HDL

c)

Distribution of Cholesterol to cells

d)

None of these

16.

_________trial involved 325 pts of Type 1 or Type 2 Diabetes mellitus in which high dose of atorvastatin reduced microalbuminuria.

a)

Planet 1

b)

Planet 2

17.

As per ______trial, Atorvastatin 10 mg daily is safe and efficacious in reducing the risk of first cardiovascular disease events, including stroke, in patients with type 2 diabetes without high LDL-cholesterol.

a)

Planet 1

b)

Planet 2

c)

Cards

d)

Armyda ACS

18.

State True or False: Atorvastatin is safe in pregnancy and lactating women.

a)

True

b)

False

19.

_______is the lipoprotein which is synthesized at the level of small intestine in exogenous pathway.

a)

VLDL

b)

IDL

c)

LDL

d)

Chylomicron

20.

Composition of Stator Gold 20 mg is

a)

Atorvastatin 10 mg+ Clopidogrel 75 mg +Aspirin 75 mg

b)

Atorvastatin 10 mg+ Clopidogrel 150 mg +Aspirin 75 mg

c)

Atorvastatin 20 mg+ Clopidogrel 75 mg +Aspirin 75 mg

d)

None of these