NEW
Font size
WorksheetsIvabradine 19-10-2023
Total questions: 10
Worksheet time: 8mins
Full form of MRS done with ivabradine of which results were published in IJAM in July 2023
Marketing Research Survey
Milestone Research Survey
Model Research Survey
Medical Research Survey
To Understand clinicians’ perspectives regarding HF management with an emphasis on HR optimization comes under which study
MRS
Ivabid OD PMOS
Initiate OD Study
Relative bioavailability study was done with Ivabradine ____mg OD compared to ___mg BID in 14 healthy human male subjects.
10, 5
15, 7.5
5, 10
7.5, 15
Proficient study was a Prospective, Randomized, Double-blind, Double Dummy, Multi Centre, Comparative Phase _____ Clinical Trial To Evaluate The Efficacy And Safety Of Ivabradine Prolonged Release Tablets In Patients With Stable Chronic Heart Failure With Systolic Dysfunction
I
II
III
IV
The non-inferiority criteria in Proficient study was that the difference in change in resting HR parameter between PR and IR treatments should not be more than _____ bpm.
2
4.5
6.5
7.5
In Proficient study, Primary end point of _____________of Ivabradine PR was established to the conventional IR formulation in patients with stable chronic heart failure with systolic dysfunction on stable dose of Ivabradine IR.
Superiority
Non-inferiority
Cardiac Pacemaker current (If) is a mixed sodium-potassium ________ current that controls the spontaneous diastolic depolarization in the sinoatrial (SA) node and hence regulates the heart rate.
Outward
Inward
As per results of MRS with Ivabradine, 46.3% of clinicians noticed a ______ bpm reduction in HR at the highest therapeutic dosage of ivabradine,
2 to 3
4 to 5
6 to 10
None of these
Majority of patients in MRS with ivabradine belong to the New York Heart Association (NYHA) categories ___ and ___, with ischemia being the most prevalent cause of HF.
I & II
II & III
III & IV
I & IV
In patients with HFrEF on ivabradine therapy, 43.6% of clinicians revealed that they _________ up-titrated ivabradine dose to 15 mg per day.
Rarely
Very Frequently
Frequently
Occasionally
