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Insulin and Glucagon - Corso - Endo Exam 2

Total questions: 24

Worksheet time: 17mins

Name
Class
Date
1.

Which of the following blood glucose levels would be considered within normal range?

a)

40 mg/dL

b)

200 mg/dL

c)

120 mg/dL

d)

80 mg/dL

2.

Glucagon

a)

Increases blood glucose

b)

Decreases blood glucose

3.

Insulin

a)

Increases blood glucose

b)

Decreases blood glucose

4.

Match the following cell types to what they excrete or their names

a)

α cells

1.

Glucagon

b)

β cells

2.

Insulin

c)

δ Cells

3.

Somatostatin

5.

All of the following are true for glucagon EXCEPT

a)

Promotes gluconeogensis

b)

Promotes glycogen breakdown

c)

Increases blood glucose

d)

Activates PKB

6.

Which of the following are effects of Insulin (SATA)

a)

Activates PKB

b)

Promotes glycolysis

c)

Promotes glycogen synthesis

d)

Promotes gloconeogenesis

e)

Promotes protein synthesis

7.

Which of the following are insulin counter regulatory hormones? (SATA)

a)

Cortisol

b)

Epinephrine

c)

Thyroid hormone

d)

Glucagon

e)

Norepinephrine

8.

Match the following metabolic homeostasis descriptions with their excess levels

a)

Hyper-osmotic state

1.

Excess sugar and amino acids

b)

Non-enzymatic glycosylation or protiens

2.

Excess glucose

c)

Atherosclerosis

3.

Excess lipids

9.

Match the following diabetes classifications with their descriptions

a)

Autoimmune destruction of β-cells. Almost undecteable insulin levels

1.

Type 1 diabetes

b)

Decreased glucokinase activity. A rare autosomal inherited form of diabetes

2.

MODY

c)

Insulin resistance due to decreased insulin production

3.

Type 2 Diabetes

d)

A special case of type 2 diabetes generally seen in pregnancy

4.

Gestational diabetes

10.

When trying to determine a patients insulin levels which of the following is the best to indicate the true levels of insulin due to it's longer half life

a)

Mature insulin

b)

Pre-pro insulin

c)

C-peptide

d)

Disulfide bonds in the body

11.

Low levels of ATP inhibit the potassium channel which induces cell depolarization leading to voltage gated calcium channels to open and insulin to be released

a)

True

b)

False

12.

Which of the following is a direct effect of sulfonylureas?

a)

Opening of voltage gated Calcium channels

b)

Opening of potassium channels

c)

Blocking of potassium channel

d)

Blocking of voltage gated calcium channels

13.

Sulfonylureas are a sufficient treatment for type 1 diabetic patients

a)

True

b)

False

14.

Which of the following enzymes is responsible for turning off glycogen synthase

a)

GSK3

b)

PKA

c)

PIP3

d)

PP1

15.

The brain has a GLUT4 receptor which is an insulin receptor

a)

True

b)

False

16.

When amylase breaks down glycogen what is the final product each of the molecules created become

a)

Maltose

b)

Maltase

c)

Glucose

d)

Maltotriose

17.

The pancreas and the salivary glands are the two organs which produce amylase

a)

True

b)

False

18.

In which of the following locations is amylase digesting starch? (SATA)

a)

Colon

b)

Stomach

c)

Intestine

d)

Mouth

19.

Match the following enzymes with the bond they cleave

a)

Glucose α 1-6

1.

isomaltase

b)

Glucose α 1-1

2.

Trehalase

c)

Galactose β 1-4

3.

Lactase

d)

Glucose α 1-2 beta

4.

sucrase

e)

Glucose α 1-4

5.

Maltase

20.

Which of the following glucose transporters has the lowest affinity to glucose and can often take in galactose or fructose

a)

Glut3

b)

Glut2

c)

Glut1

d)

Glut4

e)

Glut5

21.

Which of the following glucose transporters is insulin sensitive

a)

Glut3

b)

Glut2

c)

Glut1

d)

Glut4

e)

Glut5

22.

Which of the following glucose transporters is unique to neurons in the brain

a)

Glut3

b)

Glut2

c)

Glut1

d)

Glut4

e)

Glut5

23.

Which of the following glucose transporters allows for fructose

a)

Glut3

b)

Glut1

c)

Glut4

d)

Glut5

24.

Which of the following enzymes is tied to the body not being able to respond to dairy products

a)

Sucrase

b)

Trehalase

c)

Lactase

d)

Maltase

e)

Amylase

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