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CHE414 BCCJ Extra Credit

Total questions: 12

Worksheet time: 7mins

Name
Class
Date
1.

Which type of inhibitor directly competes for binding to an enzyme's active site?

a)

competitive

b)

noncompetitive

c)

mixed

d)

uncompetitive

2.

How do the kinetics change in competitive inhibition?

a)

Km increases

b)

Km decreases

c)

Vmax increases

d)

Vmax does not change

3.

Where is the intersection point on a Line-Weaver Burk Plot for a competitive inhibitor?

a)

on the x-axis

b)

on the y-axis

c)

a point other than the x or y-axes

d)

none (parallel lines)

4.

What type of inhibitor binds to a site on the enzyme other than the active site and elicits a conformational change that prevents product formation?

a)

mixed

b)

competitive

c)

uncompetitive

d)

noncompetitive

5.

How do the kinetics change in noncompetitive inhibition?

a)

Km decreases

b)

Km does not change

c)

Vmax decreases

d)

Vmax increases

6.

Where is the intersection point on a Line-Weaver Burk Plot for a noncompetitive inhibitor?

a)

on the x-axis

b)

on the y-axis

c)

a point other than the x or y-axes

d)

none (parallel lines)

7.

What type of inhibitor binds to an enzyme at a spot other than the active site and alters both the Km and Vmax?

a)

uncompetitive

b)

mixed

c)

noncompetitive

d)

competitive

8.

How do the kinetics change in mixed inhibition?

a)

Km increases

b)

Km decreases

c)

Vmax increases

d)

Vmax decreases

9.

Where is the intersection point on a Line-Weaver Burk Plot for a mixed inhibitor?

a)

on the x-axis

b)

on the y-axis

c)

a point other than the x or y-axes

d)

none (parallel lines)

10.

What type of inhibitor binds to the enzyme after the substrate has bound in a way that prevents the formation of product?

a)

competitive

b)

noncompetitive

c)

uncompetitive

d)

mixed

11.

How do the kinetics change in uncompetitive inhibition?

a)

Km increases

b)

Km decreases

c)

Vmax increases

d)

Vmax decreases

12.

Where is the intersection point on a Line-Weaver Burk Plot for an uncompetitive inhibitor?

a)

on the x-axis

b)

on the y-axis

c)

a point other than the x or y-axes

d)

none (parallel lines)