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U3L5A Mutation Basics

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

What are mutations?

a)

Changes in the nucleotide sequence of RNA

b)

Changes in the nucleotide sequence of DNA

c)

Changes in the nucleotide sequence of proteins

d)

Changes in the nucleotide sequence of carbohydrates

2.

Are mutations helpful or harmful?

a)

Mutations never happen

b)

Mutations are always harmful

c)

Mutations happen regularly and many are repaired by enzymes

d)

Mutations only occur in germ-line cells

3.

What are Point Mutations?

a)

Changes multiple bases at once

b)

Changes a single base

c)

Changes the entire DNA sequence

d)

Changes the entire RNA sequence

4.

What does a Frameshift Mutation look like?

a)

Deletion of a base

b)

Changes in the amino acid sequence

c)

Addition of a base

d)

No change in the DNA sequence

5.

What are Substitution Mutations?

a)

Changes the entire RNA sequence

b)

Changes the entire DNA sequence

c)

Changes multiple bases at once

d)

Changes a single base

6.

What is a disorder that arises from a Nonsense mutation?

a)

Cystic Fibrosis

b)

Sickle Cell disease

c)

Hemophilia

d)

Down Syndrome

7.

What is the result of a Silent Mutation?

a)

Changes the entire DNA sequence

b)

Causes a frameshift mutation

c)

No change in the amino acid sequence

d)

Changes the amino acid sequence

8.

What is the result of a Missense Mutation?

a)

Changes the amino acid sequence

b)

No change in the amino acid sequence

c)

Changes the entire DNA sequence

d)

Causes a frameshift mutation

9.

What is the result of a Frameshift Insertion?

a)

No change in the DNA sequence

b)

Changes in the amino acid sequence

c)

Addition of a base

d)

Deletion of a base

10.

What is the result of a Frameshift Deletion?

a)

Changes in the amino acid sequence

b)

No change in the DNA sequence

c)

Addition of a base

d)

Deletion of a base