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WorksheetsBasics of Developmental Biology
Total questions: 18
Worksheet time: 14mins
Fusion of precursor cells is an essential phenomenon in development of
Nerve
Skeletal Muscle
Spleen
Liver
Homeotic genes are responsible for
Development of anatomical structures
Homeostasis
Cell Cycle regulation
Adaption to stress
The first organ to develop during organogenesis is the
Integumentary system
Respiratory System
Excretory System
Cardiovascular System
Homeotic genes are responsible for
Maintaining gaps in segments
Provide gradient for anterior posterior axis of embryo
Codes secretory morphoges
Formation of organ at defined locations
Mosaic developmental pattern is always
Autonomous
Conditional
Non autonomous
Regulative
The model organism to study cell lineage is
Xenopus
Yeast
Caenorhabditis elegans
Drosophila
In regulative development, the prospective potency of cells
Equal to prospective fate
More than prospective fate
Lesser than prospective fate
Not determined
The myxamoebae are in the vegetative stage where they feed on bacteria but enter the aggregation stage during nutrient starvation finally fruiting body with two types of differentiated cells. It is best example of evolution of
Multicellularity
Social behaviour
Embryonic development
Pattern formation
Given are certain facts which define 'determination' of a developing embryo
A. Cells have made a commitment to a differentiation program
B. A phase where specific biochemical actions occur in embryonic cells
C. The cell cannot respond to differentiation signals
D. A phase where inductive signals trigger cell differentiation.
B and C
A and C
Only A
Only B
Which one of the following development processes. In animals is more dependent on cellular movements?
Pattern Formation
Morphogenesis
Cell differentiation
Growth
The pluripotency of the inner cell mass in mammals is maintained by a core of three transcription factors namely,
Oct 4, Sox 2, and Nanog
Oct 4, Sox 2, and Cdx2
Sox2, Nanog and Cdx2
Oct 4, Cdx2 and Nanog
During development, if a cell has committed to a particular fate, it is said to be
Pluripotent
Totipotent
Determined
Differentiated
Cell to Cell communication is important in development of an organism. The ability of cells to respond to a specific inductive signal is called
Regional specificity of Induction
Competence
Juxtracrine signaling
Instructive Interaction
The ability of cells to achieve their respective fates by interacting with other cells is known as
Autonomous specification
Conditional specification
Induction
Competence
The following are certain statements regarding stem cells
A. All types of stem cells have the ability to give rise to complete embryo
B. Multipotent stem cells are those whose commitment is limited to a relatively small subset of all possible cell types
C. Stem Cell niches allow controlled self-renewal and also survival of the cells that leave the niche
D. The pluripotency of the stem cells in an embryo is essentially maintained by Fgf8, Nanog and TGFb.
E. Adult cells may be reprogrammed to gain pluripotency by modifying the following genes: Oct 3/4, Sox2, c-myc, Klf-4
Which one of the following combinations of the statements is correct?
A, B and D
B and E
C and E
A, C and D
The Cells of Inner Cell Mass of a blastocyst stage mammalian embryo are
Totipotent
Pluripotent
Multipotent
Unipotent
Certain proteins or mRNAs that are regionally localized within the unfertilized egg and regulate development are called
Gene regulators
Morphometric determinants
Cytoplasmic determinants
Mosaic forming factors
The embryonic stem cells in mammals are derived from
Blastocoel
Inner Cell Mass
Trophoectoderm
Trophoendoderm
