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Construction of Neural Circuits Part 2

Total questions: 11

Worksheet time: 5mins

Name
Class
Date
1.

Targets must secrete ___ if the innervating neurons are to survive.

a)

tropic molecules

b)

neurotrophic factors

c)

chemoattractants

d)

chemorepellents

2.

In the nervous system, Cadherin and Protocadherin are important for ___ and require ___ as a mediator.

a)

neuronal growth and magnesium

b)
cell adhesion and calcium
c)
neurotransmission and sodium
d)

axonal guidance and potassium

3.

Neurexin, neuroligin, Ephrin B ligands and their EphB receptors are all examples of ___.

a)

Chemorepellants

b)
Cell adhesion molecules
c)

Trophic support

d)
Neurotransmitters
4.

In synaptic formation, competitive interactions such as preemptive removal involves what?

a)
the random elimination of synaptic connections
b)
the simultaneous strengthening of all synaptic connections
c)
the reinforcement of weaker synaptic connections by stronger ones
d)
the elimination of weaker synaptic connections by stronger ones
5.

When a neuron increases the number of dendrites, then:

a)
It can decrease the speed of signal transmission.
b)
It can receive more signals from other neurons.
c)
It can produce more neurotransmitters.
d)
It can lose the ability to communicate with other neurons.
6.

BDNF, NGF, and NT-3 are all examples of ___.

a)

Chemorepellants

b)
Examples of hormones
c)

Genes that affect tropic signalling

d)
Neurotrophic factors
7.

BDNF, NGF, and NT-3 bind to what type of receptors?

a)
G-protein coupled receptors
b)
Ion channel receptors
c)
Enzyme-linked receptors
d)
Tyrosine kinase receptors
8.

Structural homology among both the neurotrophins and the Trk receptors means that ___.

a)
they have completely different structures
b)
they are not related to each other
c)

ligands are capable of crossactivation

d)

their structures are identical

9.

Neurotrophic signalling endosomes do what?

a)
Inhibit the transport of neurotrophic factors within the neuron
b)

Facilitate the retrograde transport of neurotrophic factors within the neuron.

c)

Transport neurotrophic factors in an exclusively anterograde direction

d)
Cause the degradation of neurotrophic factors within the neuron
10.

Trk receptor activation could result in the following:

a)

Cell survival

b)

Neurite growth

c)

Activity-dependent plasticity

d)

All of the above

11.

Which genes help to match CNS motor neurons originating in the cervical, thoracic, and lumbar segments to their respective peripheral muscle targets?

a)

LIS1

b)

DCX

c)

Hox family

d)

RELN