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WorksheetsHypersensitivity test
Total questions: 14
Worksheet time: 28mins
Name
Class
Date
1.
In which of the following cases the Immune system would elicit an IgE response? 1) A Patient suffering from trypanosoma 2) A person who underwent a tattoo, is experiencing an inflammation and tissue necrosis after 72hrs. 3) A person experiencing an asthma attack 4) An adult eating peanut, who in his childhood was known to experience mild gastrointestinal discomfort upon consumption of peanuts 5) A young child with atopic dermatitis
a)
All except 2
b)
Only 1 and 5
c)
Only 1, 3 and 5
d)
Only 3 and 4
2.
Theoretically a Type II hypersensitive response will not manifest in which of the following scenario? 1) B+ Father/AB- mother bearing B+ fetus 2) O+ Father/A+ mother bearing O+ fetus 3) A+ Father/AB- mother bearing A+ fetus 4) AB- Father/O+ mother bearing A+ fetus 5) AB+ Father/B- mother bearing AB- fetus
a)
Only 1, 3 and 4
b)
Only 2
c)
Only 1 and 3
d)
None of the above
3.
In an immunology laboratory exercise, you are studying the response of mice injected intradermally with complete antibodies to the IgE Fc receptor (FcepsilonR1) or with Fab fragments of such antibodies. Predict the response expected with each type of antibody. Which of the following would NOT be true in this scenario? 1) the response would be dependent upon the atopic nature of mice. 2) the mice would exhibit Type 1 response independent of the allergic status. 3) the mice triggers an allergic response towards complete IgE but not to the Fab fragments. 4) Mast cells undergo degranulation upon intradermal injection and exhibit wheal and flare. 5) the mice does not trigger an allergic response towards complete IgE but does to the Fab fragments.
a)
Only 2 and 5
b)
Only 1, 3 and 5
c)
Only 2 and 4
d)
Only 5
4.
Which of the following is NOT the property of allergens? 1) either protein or glycoprotein in nature. 2) Bear multiple antigenic sites, or epitopes, per molecule. 3) Intrinsic proteolytic activity. 4) many allergens contain pathogen associated recognition receptors (PARRs) 5) many allergens enter the host via mucosal tissues at very high concentrations
a)
Only 4 and 5
b)
Only 1
c)
Only 1 and 3
d)
only 2
5.
A patient is positive for the following clinical manifestations: hives/urticaria, anemia, and glomerulonephritis showing symptoms of fever, weakness, generalized vasculitis and arthritis.Which of the following event from the history of the patient would be the cause of this hypersensitivity.1) The patient underwent a blood transfusion procedure 2 days before the symptoms manifested.2) The patient was on a 5 day regime using penicillin for treatment of bacterial infection a week before the symptoms manifested.3) The patient got stung by a bee before he was brought to the hospital4) The patient underwent a passive immunotherapy against tetanus simultaneously during treatment period for bacterial infection
a)
a) 1 and 3
b)
2, 3 and 4
c)
2 and 4
d)
Information insufficient.
6.
Which of the following conditions could possibly trigger a systemic hypersensitive reaction?1) A person was vaccinated with diphtheria antitoxin(I.V) 2) Cephalosporin has nonspecifically adsorbed to proteins on RBCs 3) An atopic individual accidentally inhaled ragweed pollen grain. 4) An active agent in hair dyes has complexed with the skin proteins 5) An individual was erroneously transfused with wrong blood type.
a)
1, 2 and 5
b)
3, 4
c)
1, 4 and 5
d)
All of the above
7.
A person got bitten by an insect and is experiencing swelling and redness at the site after 6-8hrs of the incident and the symptoms persisted for another 24 hrs. Which type of hypersensitive reaction this could be?
a)
Type I
b)
Type II
c)
Type III
d)
Type IV
8.
A patient is found to be suffering from nephritis, arthritis and vasculitis. the serum of the patient is found to be reactive to DNA, nucleoproteins, RBCs etc. which type of hypersensitivity could exhibit such symptoms?
a)
Type I
b)
Type II
c)
Type III
d)
Type IV
9.
Immune complexes have deposited, neutrophils have accumulated, lytic enzymes have been released. which of the following reactions would be evident at the site
a)
wheal and flare
b)
Arthus
c)
Granulomatus
d)
urticaria
10.
which of the following is not the treatment option for Type I reaction
a)
Omalizumab
b)
NSAID; Paracetamol
c)
Leukotriene antagonist; montelukast
d)
levocetrizine
11.
which of the following diseases do not express type 4 hypersensitive reaction
a)
leprosy
b)
malaria
c)
Toxoplasmosis
d)
Leishmaniasis
12.
A patient presents with symptoms of fever, joint pain, and a butterfly-shaped rash on the face. Which type of hypersensitivity reaction is most likely causing these symptoms?
a)
Type I
b)
Type II
c)
Type III
d)
Type IV
13.
Which of the following scenarios is least likely to trigger a Type IV hypersensitivity reaction?
a)
A person using a new skincare product and developing a rash after 24 hours
b)
An individual consuming shellfish and experiencing an allergic reaction within minutes
c)
A patient receiving a skin test for tuberculosis and developing a localized red bump after 48 hours
d)
A healthcare worker developing contact dermatitis after prolonged exposure to latex gloves
14.
In which of the following situations would a Type III hypersensitivity reaction most likely occur?
a)
A patient receiving a blood transfusion with a compatible blood type
b)
An individual with a history of hay fever inhaling pollen during allergy season
c)
A person developing serum sickness after receiving a medication for the first time
d)
A healthcare worker experiencing a delayed hypersensitivity reaction to latex gloves
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