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WorksheetsAnthracycline
Total questions: 7
Worksheet time: 4mins
What is the mechanism of action of anthracyclines involving enzyme interaction?
Inhibition of DNA polymerase
Inhibition of RNA polymerase
Inhibition of topoisomerase-II
Inhibition of topoisomerase-I
What is the maximum cumulative dose of Doxorubicin in mg/m²?
900
450-550
800
140
What is the primary method of administration for anthracyclines?
Subcutaneous
Intravenous
Intramuscular
Oral
Which of the following is NOT a side effect of anthracyclines?
Hypertension
Tissue necrosis
Peripheral neuropathy
Elevated hepatic enzymes
What is the antidote used for anthracycline extravasation that can be used topically?
Dexrazoxane
Potassium
Iron
DMSO
What is the recommended action in case of acute cardiac symptoms during anthracycline infusion?
Increase infusion rate
Stop infusion and go to the ER
Continue infusion
Refer to cardiologist
Which of the following is NOT a contraindication for anthracycline therapy?
Pregnancy
Renal impairment
Pre-existing cardiac conditions
Hypersensitivity
