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Test History of Microbiology

Total questions: 30

Worksheet time: 17mins

Name
Class
Date
1.

Viruses can have genomes made of

a)

RNA

b)

Both DNA & RNA

c)

DNA or RNA, but not both

d)

DNA

2.

Which of the following diseases wiped out approximately 50% of Europe's population during the middle ages?

a)

Anthrax

b)

Bubonic plague

c)

Smallpox

d)

Measles

3.

Which of the following is not considered a significant contribution to microbiology

a)

development of vaccines

b)

all are significant contributions

c)

invention of the microscope

d)

development of antibiotics

4.

Malaria is the infectious disease that causes the most deaths worldwide each year.

a)

True

b)

False

5.

What is the cause of stomach ulcers?

a)

Helicobacter pylori

b)

stress

c)

none of the answers is correct

d)

spicy food

6.

Which of the following is considered a traditional diagnostic procedure?

a)

culture

b)

electron microscopy

c)

Ouchterlony

d)

Gel electrophoresis

7.

HIV infections can be found in most countries around the world.

a)

True

b)

False

8.

Which of the following microscopes are routinely used in the clinical microbiology lab?

a)

A & C only

b)

B

electron microscope

c)

D

none of the above

d)

A

brightfield or lightfield microscope

e)

C

fluorescent microscope

9.

Place Koch's Postulates in the correct order.

a)

Pathogen present in all cases of the disease

b)

Pathogen isolated from the diseased host and grown in pure culture

c)

Pathogen from pure culture will cause disease when inoculated into a healthy, susceptible host

d)

Pathogen must be re-isolated from host

1)
2)
3)
4)
10.

Cell cultures are used to grow

a)

A

intracellular bacteria

b)

D

none of the above

c)

C

viruses

d)

B

all bacteria

e)

both A & C

11.

Which of the following is considered a serological diagnostic procedure?

a)

antigen titer

b)

gel electrophoresis

c)

Gram stain

d)

culture

12.

What disease did Columbus and other explorers take back to Europe?

a)

Syphilis

b)

measles

c)

smallpox

d)

tetanus

13.

What bacterial structure allows a bacteria to survive for years in a hostile environment?

a)

flagellum

b)

cell wall

c)

capsule

d)

spore

14.

The Antonine Plague that wiped out a significant portion of the Roman population was most likely caused by smallpox or measles.

a)

True

b)

False

15.

A patient comes to your clinic complaining of a sore throat.  When you perform the physical exam, his temperature is 38°C, throat is red and swollen, and you notice white patches at the back of the throat.

What is the name of the organism most likely causing the disease?

a)

Streptococcus pyogenes

b)

Staphylococcus aureus

c)

Streptococcus agalactiae

d)

Enterococcus faecalis

16.

What course of treatment do you prescribe for the patient?

a)

metronidazole

b)

penicillin

c)

tetracycline

d)

vancomycin

17.

1.       Review the image of the electrophoresis analysis.  Starting at the upper left and going to the right,

Lane 1 depicts a DNA sample that was found at a crime scene. 

Lane 2 suspect #1 DNA

Lane 3 suspect #2 DNA

Lane 4 suspect #3 DNA

Lane 5 suspect #4 DNA

Lane 6 suspect #5 DNA

Which suspect(s) is a DNA match?

a)

Lane 4, Suspect #3

b)

Suspects #1 & 2

c)

Lane 6 Suspect #5

d)

Lane 5, Suspect #4

e)

Lane 2, Suspect #1

18.

How is it possible for 2 different people to have the same DNA profile?

a)

suspects are distantly related

b)

suspects are fraternal twins

c)

suspects are identical twins

d)

laboratory error

19.

Which of the following pathogens was responsible for a pandemic that decimated nearly half of Europe's population in the 14th century?

a)

Varicella-Zoster Virus

b)

SARS-CoV-2

c)

Variola Virus

d)

Yersinia pestis

20.

Which pathogen did Christopher Columbus and other European explorers introduce to the indigenous populations of the New World, leading to widespread epidemics?

a)

Neisseria gonorrhoeae

b)

Variola virus

c)

Trichomonas vaginalis

d)

Chlamydia trachomatis

21.

Which virus was responsible for the global pandemic that occurred in 1918, significantly impacting populations worldwide?

a)

HIV

b)

Influenzae

c)

Coronavirus

d)

Hepatitis B

22.

In studying the structure of viruses in microbiology, an electron microscope can magnify objects up to ______ times.

a)

100,000

b)

100

c)

1,000,000

d)

1000

23.

Match the following scientists with their proposed theories.

a)

Koch

1.

Postulates of Germ Theory

b)

Pasteur

2.

Disproved Spontaneous Generation

c)

Aristotle

3.

Proposed Spontaneous Generation

24.

Which scientist's experiment with broth disproved Spontaneous Generation theory, supporting the concept of microbiology?

a)

Aristotle

b)

Koch

c)

Pasteur

d)

Hooke

25.

2. Which individual first observed unicellular organisms, which he called “animalcules,” using a microscope he developed?

a)

Robert Koch

b)

Louis Pasteur

c)

Thucydides

d)

Antonie van Leeuwenhoek

26.

12. Which famous scientist developed a vaccine for rabies?

a)

Louis Pasteur

b)

Robert Koch

c)

Antonie von Leeuwenhoeck

d)

Thucydides

27.
The discovery of penicillin helped in the 
a)
treatment of infections.
b)
healing of bones.
c)
discovery of viruses.
d)
search for diseases.
28.

Before the Germ Theory of Disease was widely accepted, what was a common belief about the cause of diseases?

a)

A

Diseases were caused by bad genes.

b)

B

Diseases were a result of imbalanced body humors.

c)

C

Diseases were punishments from the gods.

d)

B and C

29.

Match the following scientists with their proposed theories.

a)

Koch

1.

Postulates of Germ Theory

b)

Pasteur

2.

Disproved Spontaneous Generation

c)

Aristotle

3.

Proposed Spontaneous Generation

30.

12. Which famous scientist developed a vaccine for rabies?

a)

Louis Pasteur

b)

Robert Koch

c)

Antonie von Leeuwenhoeck

d)

Thucydides