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Seatwork 4.2 - Central Dogma and Chromosomal Mutation

Total questions: 15

Worksheet time: 9mins

Name
Class
Date
1.

Where does the DNA replication happen?

a)

Ribosome

b)

Nucleus

c)

Cytoplasm

d)

S Phase

2.

What are the three components of a nucleotide in the DNA and RNA?

a)

Sugar, phosphate, nitrogen base

b)

Sugar, phosphate, hydrogen base

c)

Sugar, phosphate, oxygen base

d)

Sugar, phosphate, protein

3.

Who are the fathers of the DNA structure?

a)

Rosalind and Franklin

b)

Simon and Crick

c)

Watson and Crick

d)

Franklin and Roosevelt

4.

What is the difference between DNA and RNA in terms of bases?

a)

RNA contains uracil in place of thymine

b)

RNA contains uracil in place of adenine

c)

RNA contains uracil in place of guanine

d)

RNA contains uracil in place of  cytosine

5.

The DNA molecule segment is: TTACGCAAG
The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.

a)

Translocation

b)

Inversion

c)

Duplication

d)

Deletion

6.

What type of chromosomal aberration in humans is illustrated in the figure?

a)

Edward's Syndrome

b)

Down Syndrome

c)

Patau Syndrome

d)

Turner Syndrome

7.

What type of mutation is shown in the picture?

a)

Deletion

b)

Inversion

c)

Duplication

d)

Translocation

8.

What is the transcribed mRNA strand for the given DNA template?

a)

3’ AUG CUC GGU AUC UGA 5’

b)

5’ AUG CUC GGU AUC UGA 3’

c)

3’ AUG CUC AUC GGU UGA 5’

d)

5’ AUG CUC AUC GGU UGA 3’

9.

What type of mutation is shown in the picture?

a)

Deletion

b)

Inversion

c)

Duplication

d)

Translocation

10.

What type of mutation is shown in the picture?

a)

Deletion

b)

Inversion

c)

Duplication

d)

Translocation

11.

Complete the mRNA sequence.

DNA sequence: TAC - CGA - GCA - CCA - TAG

mRNA sequence: AUG - GCU - (a)   - GGU - AUC

12.

What is the coded amino acid for the missing mRNA codon? **Use the abbreviated name.

DNA sequence: TAC - CGA - GCA - CCA - TAG

mRNA sequence: AUG - GCU - (a)   - GGU - AUC

13.

Complete the mRNA sequence.

DNA sequence: TAC - CGA - GCA - CCA - ATC

mRNA sequence: AUG - GCU - CGU - GGU - (a)  

14.

What is the coded amino acid for the missing mRNA codon? **Use the abbreviated name.

DNA sequence: TAC - CGA - GCA - CCA - ATC

mRNA sequence: AUG - GCU - CGU - GGU - (a)  

15.

What amino acid codes for GAU codon? **Use the abbreviated name.

(a)