WorksheetsKintsugi
Total questions: 14
Worksheet time: 10mins
Name
Trastuzumab is a ________ type of monoclonal antibody.
Murine
Chimeric
Humanized
Fully recombinant
Hermab is a brand from which company?
RPG
Glenmark
Roche
Biocon
Which of the following is a target for Trastuzumab?
BRCA
KIT
HER2
HR
Which of the following is NOT the indication for Trastuzumab?
MBC
Adjuvant breast cancer
Lung cancer
Metastatic gastric cancer
Trastuzumab in Kintsugi, is available in which of the following strengths/SKUs?
Lyophilised formulation 450mg and 150mg
Lyophilised formulation 440mg and 150mg
Liquid formulation 450mg and 150mg
Tablet formulation 440mg and 150mg
Trastuzumab controls tumor growth by _____________. More than one correct answer.
Activating ADCC
Inhibit cell proliferation
All of the above
Prevent angiogenesis
Which of the following drugs can be given in combination with trastuzumab in treatment of MBC? More than one correct answer.
Both
Doxorubicin
Cyclophosphamide
None of the mentioned
Dose of trastuzumab in breast cancer is ________.
4mg/kg initially with 2mg/kg maintenance once weekly
6mg/kg initially with 4mg/kg maintenance once weekly
8mg/kg initially with 4mg/kg maintenance once weekly
2mg/kg initially with 4mg/kg maintenance once weekly
Trastuzumab is indicated for patients with breast cancer who test positive for which biomarker?
Estrogen receptor (ER)
Progesterone receptor (PR)
HER2/neu receptor
all of the above
How is Trastuzumab typically administered?
Orally
Intramuscularly
Subcutaneously
Intravenously
__________is the time between randomization / start of treatment and an event- leading to hospitalization (Disease progression, Treatment discontinuation, Death, Relapse).
DFS
ORR
PCR
EFS
Which of the following trial suggest use of trastuzumab in EBC? More than one correct answer
HERA
NOAH
M77001
BCIRG
Therapies that work on specific protein, receptor or hormone are called as ___________
Cytotoxic drugs
Hormonal therapies
Targeted therapies
Adjuvant therapies
