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IMPCB - Nuclear Medical Physics

Total questions: 20

Worksheet time: 40mins

Name
Class
Date
1.

What scintillation camera acquisition mode stores counts sequentially with x,y coordinates and time markers?


a)
  • Cartesian Mode

b)

List Mode

c)
  • Cine Mode

d)
  • Frame Mode

2.

Below is an image and profile of a uniform intensity SPECT phantom. Why does the phantom not appear uniform?

a)
  • A bowtie filter was used

b)

There is no attenuation correction

c)
  • A bowtie filter was not used

d)
  • An insufficient number of projections were used

3.

Which of the following will not decrease collimator blurring in SPECT imaging?

a)

Decreasing septal thickness

b)
  • Increasing collimator hole length

c)
  • Decreasing collimator hole diameter

4.

Which of the following is not a SPECT acquisition parameter?

a)

Time of flight window

b)
  • Time per projection

c)
  • Degrees per step and stop

d)
  • Degrees of rotation

5.

What is the energy of a Tc-99m photon?

a)
  • 58 keV

b)
  • 1.25 MeV

c)

140 keV

d)
  • 511 keV

6.

What do PET scanners detect?

a)
  • Protons emitted after positron decay in regions of high uptake

b)
  • NaI(Tl) scintillation events

c)

Annihilation photons

d)
  • Positrons emitted from radiolabeled biologically available chemicals such as FDG

7.

PET crystals are often thicker and denser than those used in gamma cameras. Why is this?

a)

PET annihilation photons are higher energy than the photons detected via gamma camera

b)
  • Large crystals improve geometric efficiency

c)
  • PET uses time of flight information to determine point of photon emission. Therefore a small detector is unnecessary

d)
  • PET reconstruction requires much higher collection efficiency

8.

F-18 decays with a maximum positron energy of 0.63MeV and O-15 decays with a maximum positron energy of 1.74MeV. Which radionuclide provides the greater uptake localization accuracy?

a)

F-18

b)

The solution depends on the carrier molecule

c)
  • O-15

d)
  • Both produce the same error

9.

A patient preparing for a PET study has been advised by a friend, a local physics teacher, to remove his clothes during his PET scan. What effect would this have on the scan?

a)
  • Improve SNR

b)

No impact on scan

c)
  • Decrease scan time

d)
  • Improve spatial resolution

10.

Why do PET/CT devices include the CT component?

a)
  • CT imaging requires the same physical hardware at PET, so the marginal cost of a combined system is very low

b)

The linear attenuation coefficient data can be used to create a more accurate PET image

c)
  • PET images cannot be generated without the filtered back projection data provided by a CT

d)
  • This allows for direct use of the PET/CT in treatment planning


11.

Which of the following is not a method of medical radioisotope production?

a)
  • Separation from spend reactor fuel rods

b)
  • Elusion of a metastable daughter from a parent nuclide

c)

Neutron bombardment in a cyclotron

d)
  • Bombarding with neutrons in a reactor

12.

A radiopharmaceutical has a biological half life of 74 minutes and an effective half life of 44 minutes. What radionuclide is used?

a)

F-18: t1/2 = 109.8 minutes

b)
  • Ga-68: t1/2 = 68.3 minutes

c)

C-11: t1/2 = 20.4 minutes

d)
  • O-15: t1/2 = 2.0 minutes

13.

The term Moly Cow refers to what?

a)
  • Mo-99 flood correction factor

b)
  • A shielded radiation waste storage device

c)
  • Molybdenum-99 based radiotracers commonly used in GI studies

d)

A hospital based Tc-99m generator

14.

Find the biological half life an I-125 molecule with an effective biological half life of 55 days

a)
  • 3.2 years

b)

2.0 years

c)

318 days

d)

571 days

15.

What is the half-life of F-18?

a)
  • 10 minutes

b)
  • 20 minutes

c)

110 minutes

d)

2 minutes

16.

True or False: For the same administered activity, F-18 administration will result in more dose to the patient than O-15. Ignore biological half-life.

a)

False, integral dose is not influenced by half-life

b)

True, 18F's longer half life will result in higher integral dose for the same initial activity

c)

False, 18F's longer half life will result in lower integral dose for the same initial activity

d)
  • False, 18F's shorter half life will result in lower integral dose for the same initial activity

e)
  • True, 18F's shorter half life will result in higher integral dose for the same initial activity.

17.

A dose calibrator uses what type of detector?

a)
  • Proportional counter

b)
  • NaI scintillator

c)

Well-type ionization chamber

d)
  • Fluke 481 meter

18.

The (n, γ) reaction yields a ____ of the parent atom

a)
  • Isobar

b)
  • Isotone

c)
  • Isomer

d)
  • Isotope

19.

Which parameter does not impact geometric efficiency of a counting study?

a)

Sample placement

b)

Sample volume

c)

Sample container

d)

Sample activity

20.

Why does the accuracy of a well counter decline for measurement of very high activity samples?

a)

Coincidence loss

b)

Geometric inefficiency increases

c)

Accuracy is not effected by sample activity

d)

Sample self attenuation