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WorksheetsCELL CYCLE CONTROL SYSTEM
Total questions: 15
Worksheet time: 8mins
What is checked at the G1 checkpoint in the cell cycle?
Chromosome number, cell volume, enzyme activity, and cell membrane
Which checkpoint ensures that DNA replication is complete and the replicated DNA is not damaged?
What happens if a cell receives a go-ahead signal at the G1 checkpoint?
Which checkpoint ensures that all chromosomes are attached to spindle fibers before proceeding to anaphase?
G1 checkpoint
G2 checkpoint
S checkpoint
M checkpoint
Which molecule acts as a go-ahead signal at cell cycle checkpoints?
What will happen if any chromosomes are not attached to spindle fibers during mitosis?
The cell will receive a stop signal
What gene is activated in response to DNA damage or cell cycle abnormalities?
p21
What is the primary role of the p53 gene when activated?
Encode a protein activator that activates other genes
Which gene is activated by the protein produced by the p53 gene?
What does the p21 gene encode for?
Cyclin-dependent kinase inhibitor
DNA repair enzyme
Spindle fiber
What is the consequence of the Cdk inhibitor binding to Cdks?
Why is it important to arrest the cell cycle when DNA damage is detected?
To allow time for DNA repair
What might happen if the p53 gene is mutated and non-functional?
What is the main function of the p53 protein in the cell cycle?
To initiate DNA replication
To promote cell growth
To act as a tumor suppressor by regulating the cell cycle
To assist in chromosome separation during mitosis
What is the result of a functional p53 gene in the presence of DNA damage?
The cell cycle progresses without interruption
DNA replication is halted and repair mechanisms are activated
The cell immediately enters mitosis
Spindle fibers are detached from chromosomes
