Which of the following indicates positive bronchoprovocation testing (multiple answers may be correct)?

Which of the following blood gases suggests impending respiratory failure in an acute asthma exacerbation?

Which of the following ventilator waveforms suggests status asthmaticus?

Which of the following is not appropriate for ventilator management of a patient with status asthmaticus?

A 35 year-old male with a history of asthma presents to your office for a new patient visit. He notes that he currently has asthma symptoms 4-5 days a week. He denies any nighttime awakenings. He is currently maintained on budesonide-formoterol (Symbicort) 160-4.5 mcg twice daily and uses his albuterol 3-4 times weekly for rescue. You reviewed his inhaler technique and adherence and both are appropriate. His PFTs show an FEV1 of 75% predicted. He has not had any exacerbations in the last year.

Which of the following best characterizes this patient’s asthma severity?

A 29 year old female with a history of allergic rhinitis, nasal polyposis and asthma presents to your clinic for ongoing management of her asthma. Her symptoms remain poorly controlled, with symptoms throughout the day and almost every night in spite of high dose fluticasone-salmeterol (Advair) 500-50 mcg twice daily and nightly montelukast. She has required frequent treatments with systemic steroids for asthma exacerbations. Eosinophil count is 450, total IgE is 1050.

Which of the following biologic therapies would not be indicated?

A 55-year-old woman presents to your clinic for the first time. She has recent moved from out of state. She reports a longstanding history of poorly-controlled asthma with at least yearly exacerbations. She endorses a history of rhinosinusitis with occasional epistaxis, GERD, obesity and neuropathy. Physical exam reveals tender, raised nodules on the extensor surface of her elbows. Current medications include fluticasone-umeclidinium-vilanterol (Trelegy) 200-62.5-25 mcg 1 inhalation daily, montelukast 10 mg nightly, cetirizine 10 mg daily, fluticasone nasal spray 50 mcg daily, pantoprazole 40 mg daily and gabapentin 300 mg TID. Spirometry reveals mild airflow obstruction with positive bronchodilator response. Chest radiography today demonstrates patchy bilateral opacities in the left upper lobe and right lower lobe. Review of prior chest radiography from 2 years prior demonstrates patchy opacities in the right lower lobe.

Which of the following laboratory values would be expected in this patient?