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Flow Cytometry Overview Workshop

Total questions: 15

Worksheet time: 1hrs 5mins

Name
Class
Date
1.

What technology provides rapid multi-parametric analysis of single cells in solution?

a)

Flow Cytometry

b)

Microscopy

c)

Spectrometry

d)

Centrifugation

2.

What are the two types of light scatter measured in flow cytometry?

a)

Forward scatter and side scatter

b)

Fluorescent scatter and light scatter

c)

Visible scatter and invisible scatter

d)

None of the above

3.

What is the purpose of fluorescent reagents in flow cytometry?

a)

To analyze cell populations

b)

To purify cells

c)

To provide light signals

d)

All of the above

4.

What is the main function of a cell sorter in flow cytometry?

a)

To analyze cells

b)

To purify and collect samples

c)

To measure light scatter

d)

To transfect cells

5.

What type of cytometer uses ultrasonic waves for better focusing?

a)

Acoustic Focusing Cytometer

b)

Traditional Flow Cytometer

c)

Mass Cytometer

d)

Imaging Cytometer

6.

What is the role of dichroic filters in flow cytometry?

a)

To pass specific wavelengths of light

b)

To generate light signals

c)

To analyze cell populations

d)

To collect data

7.

What is the main advantage of imaging flow cytometers?

a)

They combine flow cytometry with fluorescence microscopy

b)

They are cheaper than traditional cytometers

c)

They require less sample preparation

d)

They can only analyze single cells

8.

What is the primary detection method used in mass cytometers?

a)

Time-of-flight mass spectrometry

b)

Fluorescent detection

c)

Light scatter detection

d)

Immunostaining

9.

What is the purpose of MHC multimers in antigen specific responses?

a)

To bind to T cells that recognize the antigen

b)

To stimulate immune cells

c)

To measure cytokine production

d)

To analyze cell proliferation

10.

What is the role of Annexin V in apoptosis detection?

a)

To bind to phosphatidylserine

b)

To label DNA breaks

c)

To measure mitochondrial potential

d)

To stain for viability

11.

What does the TUNEL technique label in apoptosis?

a)

DNA breaks

b)

Caspase activity

c)

Mitochondrial potential

d)

Cytokine production

12.

Una de las proteínas fluorescentes usadas comunmente es la: (siglas)

(a)  

13.

La 3H-Thimidina es uno de los de los marcadores de proliferación más usados en la citometría de flujo. Seleccione uno de los análogos de este importante marcador:

a)

Indo-1

b)

Dapi

c)

BrdU

d)

Anexina V

14.

El análisis de los resultados de una citometría de flujo se hace mediante:

a)

Histogramas

b)

Dispersogramas

c)

Puntogramas

d)

Celulogramas

15.

Aparte de los marcadores membranales CD, la reacción antígeno-anticuerpo y el tamaño de las células, que otra propiedad técnica utiliza la citometría de flujo para marcar e identificar las células:

a)

El MHC (Complejo MAyor de Histocompatibildiad)

b)

El TCR

c)

La fluorescencia

d)

La espectrometría de masas