WorksheetsComplement Cascade Quiz
Total questions: 15
Worksheet time: 8mins
What initiates the formation of the C1 complex in the complement cascade?
Antigen binding to IgG
C3 hydrolysis
C5 cleavage
Membrane attack complex formation
Which pathway is involved in the formation of C3 convertase?
Classical pathway
Alternative pathway
Both classical and alternative pathways
Neither pathway
What is the result of C3 hydrolysis in the complement cascade?
Formation of C3 convertase
Cleavage of C5
Production of C3b and C3a fragments
Formation of the membrane attack complex
What does C3b cleave in the complement cascade?
C2
C4
C5
C9
Which components form the cylindrical membrane attack complex?
C3b, C3a
C5b, C6, C7, C8, C9
C2a, C4b
C1 complex
What happens to the cell at the end of the complement cascade?
It divides
It swells and bursts
It shrinks
It becomes dormant
Which fragment is not directly involved in forming C3 convertase?
C2a
C4b
C3b
C5b
What is the role of C3 convertase in the complement cascade?
Initiates antigen binding
Hydrolyzes C3
Forms the membrane attack complex
Cleaves C5
Which of the following is a fragment produced by C3 hydrolysis?
C5a
C3a
C4b
C2a
What is the function of C5b in the complement cascade?
Initiates C1 complex formation
Forms part of the membrane attack complex
Hydrolyzes C3
Cleaves C2
Which component is not part of the membrane attack complex?
C5b
C6
C3a
C9
What is the primary function of the complement cascade?
To produce antibodies
To destroy pathogens by cell lysis
To activate T-cells
To inhibit antigen binding
Which fragment is responsible for cleaving C5?
C3a
C3b
C4b
C2a
What is the role of C2a and C4b in the complement cascade?
Form C3 convertase
Cleave C5
Form the membrane attack complex
Hydrolyze C3
Which pathway is not involved in the complement cascade?
Classical pathway
Alternative pathway
Lectin pathway
None of the above
