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TUTORIAL 2

Total questions: 10

Worksheet time: 3mins

Name
Class
Date
1.

Type III hypersensitivity is characterized by:

a)

Antibody-mediated cytotoxicity against cells

b)

Immune complex deposition activating complement

c)

T-cell-mediated cytotoxicity

2.

Type I hypersensitivity reactions involve:

a)

IgG antibodies and complement

b)

IgE antibodies and mast cells

c)

Immune complex deposition

3.

Which type of hypersensitivity is primarily T-cell mediated and delayed?

a)

Type II

b)

Type III

c)

Type IV

4.

Which of the following antibodies is most commonly associated with MG?

a)

Anti-AChR

b)

Anti-dsDNA

c)

Anti-thyroid peroxidase

5.

Which mechanism best describes acute cellular rejection?

a)

NK cells destroying graft tissue independently

b)

Pre-existing antibodies binding donor endothelium

c)

T lymphocytes recognizing foreign antigens on transplanted tissue

6.

Which of the following is an example of Type II hypersensitivity?

a)

Hemolytic transfusion reaction

b)

Serum sickness

c)

Contact dermatitis

7.

Which graft type uses tissue from the same individual?

a)

Allograft

b)


Isograft

c)

Autograft

8.

Which type of rejection is most likely to cause long-term graft failure?

a)

Hyperacute rejection

b)

Acute cellular rejection

c)

Chronic rejection

9.

Which mechanism is mainly responsible for tissue damage in SLE?

a)

Direct cytotoxicity by T cells

b)

Immune complex deposition and complement activation

c)

NK-cell mediated killing

10.

The typical timing of hyperacute rejection is:

a)

Minutes to hours after transplantation

b)

Days to weeks

c)

Months to years