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WorksheetsTutorial 2: Carbohydrate metabolism
Total questions: 15
Worksheet time: 8mins
Where does glycolysis occur in the cell?
Mitochondria
Nucleus
Cytosol
Ribosome
Which enzyme catalyzes the conversion of 3-phosphoglycerate to 2-phosphoglycerate?
Phosphofructokinase
Hexokinase
Phosphoglyceromutase
Phosphoglycerokinase
What is the rate-limiting step in glycolysis?
Conversion of glucose to glucose-6-phosphate
Phosphorylation of fructose-6-phosphate
Conversion of 2-phosphoglycerate to phosphoenolpyruvate
Oxidation of glyceraldehyde-3-phosphate
Which molecule is the final product of glycolysis under aerobic conditions?
Lactate
Acetyl-CoA
Oxaloacetate
Pyruvate
In the fed state, which hormone promotes glycolysis by increasing fructose 2,6-bisphosphate levels?
Glucagon
Insulin
Adrenaline
Cortisol
Which enzyme converts pyruvate to lactate?
Pyruvate dehydrogenase
Pyruvate carboxylase
Lactate dehydrogenase
Aldolase
Which enzyme catalyzes the first step of the TCA cycle?
Isocitrate dehydrogenase
Citrate synthase
α-Ketoglutarate dehydrogenase
Malate dehydrogenase
What is the net yield of NADH from one cycle of the TCA cycle?
1 NADH
2 NADH
3 NADH
4 NADH
What happens to fructose in the liver?
It is directly converted to glucose.
It is phosphorylated to fructose-1-phosphate.
It is oxidized to lactate.
It bypasses glycolysis.
Which of the following enzyme deficiency causes fructose intolerance?
Lactase deficiency
Aldolase B deficiency
Pyruvate kinase deficiency
Pyruvate kinase deficiency
What is the main purpose of gluconeogenesis?
Breakdown of glucose into ATP
Synthesis of glucose from non-carbohydrate precursors
Storage of glucose as glycogen
Oxidation of glucose to carbon dioxide and water
Which hormone activates glycogen phosphorylase in the fasting state?
Insulin
Glucagon
Epinephrine
Cortisol
What is the main function of the pentose phosphate pathway?
Production of glucose
Generation of NADPH and ribose 5-phosphate
Breakdown of glycogen
Oxidation of pyruvate
What is the primary purpose of the Cori cycle?
Breakdown of glycogen to glucose in muscle
Oxidation of glucose to pyruvate
Synthesis of fatty acids
Conversion of lactate in muscles to glucose in the liver
Which enzyme deficiency causes Von Gierke’s disease?
Hexokinase
Pyruvate kinase
Glucose 6-phosphatase
Glycogen synthase
