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WorksheetsDevelopment of the Nervous System
Total questions: 14
Worksheet time: 11mins
At what stage of development are the three germ layers formed?
Cleavage
Blastulation
Gastrulation
Organogenesis
What is the primary structure through which epiblast cells migrate during gastrulation?
Neural groove
Primitive streak
Notochord
Somites
Which germ layer forms the nervous system?
Endoderm
Mesoderm
Ectoderm
Hypoblast
What structure is formed by epiblast cells displacing the hypoblast during gastrulation?
Mesoderm
Endoderm
Neural plate
Ectoderm
What is the role of the notochord in embryonic development?
Formation of somites
Neural tube closure
Apoptosis regulation in neural structures
Formation of Vertebra column
During an embryology class, Thomas learned about a condition that results from the failure of the cranial neural tube to close. Which of these best describes this condition?
Spina bifida
Anencephaly
Hydrocephalus
Lissencephaly
Grace is studying different types of spina bifida for and read about the mildest form of spina bifida. Which is it?
Meningocele
Myelomeningocele
Myeloschisis
Occulta
The closure of the rostral neuropore leads to the formation of which primary brain vesicles?
Telencephalon, diencephalon, myelencephalon
Prosencephalon, mesencephalon, rhombencephalon
Telencephalon, diencephalon, mesencephalon
Mesencephalon, metencephalon, myelencephalon
What brain condition involves disruptions in neural migration resulting in a smooth brain?
Hydrocephalus
Spina bifida
Lissencephaly
Myelomeningocele
Which structure is an adult derivative of the notochord?
Intervertebral discs
Vertebral column
Nucleus pulposus
Meninges
A 9-month-old infant presents with progressive motor delay, spasticity, and hyperreflexia. Neurological examination reveals increased tone in the lower limbs and brisk deep tendon reflexes. Brain imaging shows diffuse white matter abnormalities. He was later diagnosed with a demyelinating disorder in the CNS.
What cell type is responsible for myelination in the central nervous system?
Astrocytes
Oligodendrocytes
Schwann cells
Microglial cells
A 10-month-old infant is brought to the clinic with delayed motor milestones, hypotonia, and reduced reflexes. Nerve conduction studies reveal significantly slowed conduction velocities.
Family history reveals a sibling with similar symptoms in infancy. Genetic testing confirms a diagnosis of an inherited demyelinating neuropathy.
What cell type is responsible for myelination in the peripheral nervous system?
Ependymal
Oligodendrocytes
Schwann cells
Microglial cells
Anaya is expecting her first child and wants to ensure she is getting the right nutrients to support her baby's development. Which nutrient is critical in reducing neural tube defects?
Vitamin C
Iron
Calcium
Folic acid
Vitamin D
The failure of the neural tube to close completely leads to defects such as spina bifida and anencephaly. Which part of the neural tube fails to close in spina bifida?
Middle part of the neural tube
Caudal part of the neural tube
Rostral part of the neural tube
