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Pedigrees & Mutations

Total questions: 23

Worksheet time: 35mins

Name
Class
Date
1.

Mutations can benefit humans because they can:

a)

Cause illness

b)

Make an organism more suited to live in its environment.

c)

Make organisms live shorter lives

d)

Cause organisms to grow extra limbs.

2.

A mutation is defined as:

a)

A change in the cell's structure

b)

Anything that changes in an embryo

c)

Any change in the physical features of a human

d)

A change in the DNA sequence

3.
What causes mutations?
a)
Mistakes in replication or environmental substances
b)
The amino acids
c)
Passed down by genetics
d)
It's how your born
4.

ATTTGAGCC- Original

ATTGAGCC - Mutated

The example above is an example of a

a)

Insertion

b)

Point mutation

c)

Deletion

d)

Substitution

5.

Mutations are a source of genetic diversity.

a)

True

b)

False

6.

The survival of a species depends on its ability to adapt to changes in the environment. Which statement correctly describes a way that mutations increase the likelihood that a species will survive in a changing environment?

a)

Mutations are a source of variation in the species

b)

Mutations are the cause of disease in the species

c)

Mutations are not harmful when they occur in somatic cells

d)

Mutations are always passed on to subsequent generations

7.

In a pedigree, which shape represents a male?

a)

circle

b)

square

8.

How many individuals are there in the 3rd generation?

a)

1

b)

2

c)

4

d)

6

9.

How are individuals III-2 and II-4 related?

a)

Brother and sister

b)

Dad and daughter

c)

Uncle and niece

d)

Grandfather and granddaughter

10.

The trait this pedigree traces is recessive because it skips a generation and individuals can be carriers. What is the most likely genotype for person III-3?

a)

GG

b)

Gg

c)

gg

11.
How many kids did the mother and father from the first generation have?
a)
2
b)
4
c)
5
d)
6
12.
There are no carriers for Huntington's Disease- you either have it or you don't. Is Huntington's disease caused by a dominant or recessive trait?
a)
Dominant
b)
Recessive
13.
This pedigree represents the inheritance of hemophilia in this family. How many of the females have the hemophilia trait?
a)
8
b)
5
c)
2
d)
3
14.
Huntington's Disease is a dominant trait.
What is the correct genotype for individual I-2?
a)
HH
b)
Hh
c)
hh
d)
H_
15.
Does this pedigree show a dominant or recessive trait?
a)
Dominant
b)
Recessive
16.
What is the genotype of the mother?
a)
BB
b)
bb
c)
Bb
d)
BB or Bb
17.
What is the genotype of the father?
a)
AA
b)
aa
c)
Aa
d)
AA or aa
18.

Generation 2 individuals 5 and 6 are

a)

brother and sister.

b)

cousins.

c)

married.

d)

not related.

19.

The karyotype diagram below represents a human female with the genetic disorder known as Turner syndrome. Chromosomal analysis of this karyotype reveals the mutation is a result of

a)

a missing X chromosome

b)

a missing Y chromosome

c)

an extra 21 chromosome

d)

missing chromosome #9

20.

The karyotype diagram below represents a human male. Chromosomal analysis of this karyotype reveals the abnormality in this karyotype is:

a)

a missing X chromosome

b)

a missing Y chromosome

c)

an extra 21 chromosome

d)

missing chromosome #9

21.

Homologous pairs:


(select all that apply)

a)

Have the same genes on them

b)

May have different alleles

c)

Each comes from one parent

d)

Combine to give you your genotypes

22.

By looking at the chromosomes how can you tell that this person is biologically female?

a)

Because there are two X chromosomes

b)

Because there are more chromosomes than in a male

23.

This is known as Edwards Syndrome, can you identify the chromosomal mutation?

a)

Chromosomes 1 and 2 are bent

b)

There is no Y chromosome

c)

This persons chromosomes are normal

d)

There are 3 of chromosomes 18