WorksheetsR,S Chirality
Total questions: 7
Worksheet time: 4mins
Chirality...
... is a property of a molecule, not a mixture
... can be quantified by measuring optical rotation
... requires a molecule with a chiral centre
... can only be observed at a molecular level
How can you prove if a novel enantiopure compound has R or S configuration?
Derivatising (e.g. Mosher's ester) then 1H NMR
Measuring [α]D
Chiral HPLC
X-ray crystallography
How many possible stereoisomers does Baulamycin have? (7 stereocentres)
7
14
49
128
How many possible stereoisomers does tartaric acid have?
1
2
3
4
Two enantiomers will have the same...
IC50
Solubility
Microsomal clearance
In vivo PK
This reaction is...
Asymmetric
Stereospecific
Stereoselective
None of the above
What is the difference between a chiral ligand and a chiral auxiliary?
The chiral auxiliary is made from the chiral pool
The chiral ligand is used catalytically
The chiral auxiliary is covalently bound to the starting material
None are correct
