WorksheetsGastric System Physiology
Total questions: 14
Worksheet time: 11mins
In a study of the secretion of gastrointestinal hormones, portal concentrations are measured in a rat during luminal perfusion of buffered salt solutions at various pH levels. Which of the following hormones will increase during perfusion with a buffered solution at pH 3.0?
Cholecystokinin
Gastrin
Glucose-dependent insulinotropic peptide
Motilin
Secretin
Cholecystokinin (CCK) has some gastrin-like properties because both CCK and gastrin
Released from G cells in the stomach
Released from I cells in the duodenum
Members of the secretin-homologous family
Have five identical C-terminal amino acids
Have 90% homology of their amino acids
A patient suffering from anemia comes to his physician complaining of frequent bouts of gastroenteritis. A blood test reveals the presence of antibodies directed against gastric parietal cells. The anemia in this patient is attributable to the hyposecretion of which gastric product?
Histamine
Gastrin
Pepsinogen
Intrinsic factor
Hydrochloric acid
Two medical students studying for their physiology exam decided to take a break for a lunchtime hamburger. Before reaching the cafeteria, nervous impulses from the dorsal vagal complex will initiate gastric acid secretion by triggering release of which neurotransmitter from the enteric nervous system?
Norepinephrine
Vasoactive intestinal polypeptide
Substance P
Gastrin-releasing peptide
Nitric oxide
A 3-year-old boy is brought to his pediatrician for an evaluation because of failure to thrive and frequent diarrhea characterized by pale, bulky, foul-smelling stools. Sweat chloride concentrations are measured and found to be elevated. Diminished secretion of which pancreatic product is most likely to be the primary cause of the patient’s apparent fat malabsorption?
Lipase
Procolipase
Monitor peptide
Cholecystokinin
Bicarbonate
A researcher conducts a study of the regulation of salivary secretion in a group of normal volunteers under various conditions. Which of the following conditions would be expected to be associated with the lowest rates of secretion?
Chewing gum
Undergoing a mock dental exam
Sleep
Exposure to a nauseating odor
Resting control conditions
A 50-year-old female patient who has suffered for several years from severe dryness of her eyes due to inadequate tear production is referred to a gastroenterologist for evaluation of chronic heartburn. Endoscopic evaluation reveals erosions and scarring of the distal esophagus. Reduced production of which salivary product most likely contributed to this tissue injury?
Bicarbonate
Lactoferrin
IgA
Mucus
Amylase
A newborn baby is brought to the pediatrician suffering from severe diarrhea that worsens after feeding. The symptoms diminish when nutrients are delivered intravenously. The child most likely has a mutation in which of the following intestinal transporters?
Na+, K+ ATPase
NHE3
SGLT-1
H+, K+ ATPase
NKCC1
An infant who was previously healthy but is displaying symptoms of acute diarrhea and dehydration after an infection is given an oral solution of glucose and electrolytes (Pedialyte). What membrane protein accounts for the ability of this solution to provide rapid hydration?
Sucrase-isomaltase
SGLT-1
CFTR
Chloride-bicarbonate exchanger
Lactose-phlorizin hydrolase
A 6 year old child was brought to her pediatrician exhibiting signs of malnutrition, diarrhea, and edema of the extremities. Duodenal aspirates were obtained at endoscopy after intravenous administration of cholecystokinin, and was found to be incapable of protein hydrolysis at neutral pH unless a trace amount of trypsin is added that by itself would not result in appreciable hydrolysis. The patient was most likely suffering from a deficiency in which of the following?
Pepsinogen
PepT1
Trypsinogen
Carboxypeptidases
Enterokinase
In infants, defecation often follows a meal. The cause of colonic contractions in this situation is:
histamine
increased circulating levels of CCK
the gastrocolic reflex
increased circulating levels of somatostatin
the enterogastric reflex
A patient who has undergone a partial gastric resection to remove a tumor reports to his primary care physician that he has experienced several episodes of nausea, cramping, dizziness, sweating and a rapid heart rate after ingesting sugary beverages. His symptoms are caused in part by
increased blood pressure
increased secretion of acid
increased secretion of CCK
hypoglycemia
hyperglycemia
A scientist studies the regulation of gastric motility by placing a pressure sensor in the stomach of a mouse that remotely reports intragastric pressure over time. She notes that gastric pressures seldom rise above the levels that breach the lower esophageal sphincter, even when the stomach is filled with a meal and its volume is expanded considerably as a result. Which process is responsible for this finding?
Peristalsis
Gastroileal reflex
Segmentation
Stimulation of the vomiting center
Receptive relaxation
A patient is referred to a gastroenterologist for evaluation of suspected small bowel bacterial overgrowth. Motility studies reveal slowed gastrointestinal transit during fasting. The patient’s symptoms are most likely due to a deficit in which of the following substances?
Motilin
NO
CCK
VIP
Secretin
