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Biotechnology tools and techniques Quiz

Total questions: 25

Worksheet time: 23mins

Name
Class
Date
1.

What does biotechnology involve?

a)

Using chemical processes

b)

Using biological processes

c)

Using mechanical processes

d)

Using electrical processes

2.

For how long have biological processes been utilized in biotechnology?

a)

Hundreds of years

b)

Thousands of years

c)

Decades

d)

Centuries

3.

Human cells have about ​ (a)   , and ​ (b)   are the same across all humans (Identical twins are the exception, sharing 100% of their DNA). Despite this similarity, the ​ (c)   difference—around ​ (d)   —allows for distinguishing individuals. These differences occur at specific locations called ​ (e)   and are analyzed in DNA profiling.

Choose from the below words
3 billion base pairs
99.9%
0.1%
3 million base pairs
loci
4.

What must be isolated from histone proteins in the DNA extraction process?

a)

Chromosomes

b)

Nucleus

c)

Organelles

d)

DNA

5.

What are gene probes made of?

a)

Double-stranded DNA or RNA segments

b)

Single-stranded DNA or RNA segments

c)

Proteins

d)

Lipids

6.

What is identified when gene probes bind to specific genes?

a)

The gene of interest

b)

The protein of interest

c)

The cell of interest

d)

The enzyme of interest

7.

DNA probes are short, ​ (a)   pieces that find and bind to ​ (b)   . The probe is ​ (c)   so it can be detected. When mixed with DNA, it ​ (d)   to matching sequences. Scientists then use special techniques to see where the probe has bound, helping to ​ (e)   or study specific genes.

Choose from the below words
specific DNA sequences
labelled
attaches
identify
single-stranded DNA
8.

What is the function of free DNA nucleotides in PCR?

a)

To bind to primers

b)

To assemble new DNA copies

c)

To act as a template

d)

To denature DNA

9.

What is the first step in the polymerase chain reaction (PCR) process?

a)

Annealing

b)

Denaturing

c)

Extension

d)

Replication

10.

Often, during PCR, the DNA, enzyme and nucleotide mixture is heated to temperatures well in excess of 60-70 degrees Celsius. State why it is necessary to heat the DNA in this manner.

4 lines
11.

What is the purpose of heating the DNA to 95°C in the PCR process?

a)

To bind primers

b)

To denature proteins

c)

To break hydrogen bonds

d)

To synthesize RNA

12.

What is the main purpose of the polymerase chain reaction (PCR)?

a)

To sequence DNA

b)

To amplify DNA

c)

To mutate DNA

d)

To degrade DNA

13.

During the annealing step of PCR, what attaches to the target sequence?

a)

DNA polymerase

b)

RNA primers

c)

Short DNA primers

d)

Nucleotides

14.
Electrophoresis separates (a)   , RNA, or (b)   based on size using an electric field. A gel is prepared and placed in a (c)   solution. DNA samples, along with a reference ladder, are loaded into wells. When an electric current is applied, negatively charged DNA moves toward the positive electrode, with smaller fragments traveling farther. After running, the gel is (d)   to visualize the separated DNA bands under (e)   .
Choose from the below words
DNA
proteins
buffer
stained
UV light
15.

What happens to the DNA template during the denaturation step?

a)

It is cooled to attach primers

b)

It is heated to separate strands

c)

It is cut into fragments

d)

It is replicated

16.

Name 2-3 potential concerns or issues associated with the collection and storage of human genetic data.

4 lines
17.

Which step in PCR involves the attachment of primers?

a)

Denaturation

b)

Annealing

c)

Extension

d)

Replication

18.

Which of the following is NOT a step in the PCR process?

a)

Denaturation

b)

Annealing

c)

Extension

d)

Transcription

19.

What do both types of electrophoresis separate?

a)

Molecules based on color

b)

Molecules based on size and charge

c)

Molecules based on temperature

d)

Molecules based on density

20.
Capillary electrophoresis has multiple applications including (a)   and (b)   . The general principles of electrophoresis still apply: DNA fragments move from the (c)   electrode to the (d)   electrode. (e)   DNA fragments move faster and further through the tube than longer ones.
Choose from the below words
DNA sequencing
DNA profiling
negative
positive
Shorter
21.

How do smaller molecules behave in electrophoresis?

a)

They move slower

b)

They move faster

c)

They remain stationary

d)

They dissolve

22.

In gel electrophoresis, towards which terminal do DNA fragments move?

a)

Positively charged terminal

b)

Negatively charged terminal

c)

Neutral terminal

d)

Ground terminal

23.

What are some applications of capillary electrophoresis?

a)

DNA sequencing and DNA profiling

b)

Protein synthesis and cell division

c)

Photosynthesis and respiration

d)

Fermentation and distillation

24.

In capillary electrophoresis, DNA fragments move from which electrode to which electrode?

a)

Negative to positive

b)

Positive to negative

c)

Neutral to positive

d)

Neutral to negative

25.

PCR is a technique used to make many copies of a specific (a)   segment. It works like a photocopier for DNA, allowing scientists to study small amounts of DNA by making millions of copies. Steps of PCR 1. (b)   (95°C) The DNA is heated to separate its two strands. 2. (c)   (50-65°C) Short DNA primers attach (bind) to the specific DNA sequence that needs to be copied. 3. (d)   (72°C) A special enzyme called (e)   adds new DNA bases, building a new strand. These steps are repeated 30-40 times, doubling the DNA each cycle, creating millions of copies in just a few hours!

Choose from the below words
DNA
Denaturation
Annealing
Extension
Taq polymerase