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DNA Structure and Replication

Total questions: 20

Worksheet time: 1hrs 4mins

Name
Class
Date
1.

This scientist used heat and found it denatures proteins while DNA is heat stable. (mice experiment)

a)

Chargaff

b)

Griffith

c)

Watson & Crick

d)

Hershey & Chase

2.

What is DNA made up of?

a)

nucleotides

b)

cytoplasm

c)

RNA

d)

cells

3.

What makes up the SIDES of a DNA ladder? (backbone)

a)

nitrogen bases

b)

Deoxyribose sugars & phosphates

c)

genes & chromosomes

d)

RNA

4.

What makes up the rungs (center) of a DNA ladder?

a)

sugars & phosphates

b)

nitrogen bases

c)

sugars

d)

genes & chromosomes

5.

Studied bacteriophages - phages are composed of protein and DNA. Determined DNA enters the host cell based upon tracers.

a)

Chargaff

b)

Hershey & Chase

c)

Watson & Crick

d)

Avery, McCarty and Macleod

6.

DNA is located in the _____ in eukaryotic cells.

a)

nucleus

b)

cytoplasm

c)

mitochondria

d)

ribosome

7.

Eukaryotic cells (plants & animals) have

a)

one origin of replication site

b)

have many origin of replication sites

8.

According to the Base pair rule, if a DNA molecule contains 1500 adenines how many thymine's will it contain?

a)

1500

b)

500

c)

0

d)

1000

9.

DNA Replication is considered "semi-conservative" because

a)

both original DNA strands are a part of one new DNA strand

b)

one strand of original DNA is on the new DNA strand

10.

Step 2 of Replication: Primase...

a)

unzips DNA

b)

lays down primer; tells polymerase where to start adding nucleotides

c)

adds nucleotides

d)

glues okazaki fragments

11.
Which enzyme fixes the Okazaki fragments in the lagging strand?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
12.

Problems with replication

a)

Error rate is 1 in 10 billion; cannot complete ends of DNA - so gets shorter each replication

b)

DNA gets longer with each replication

c)

the ends of DNA are able to be copied

13.
Guanine bonds with ______________.
a)
Adenine
b)
Guanine
c)
Cytosine
d)
Thymine
14.

Nitrogen bases are held by what type of bonds?

a)

Covalent Bonds

b)

Hydrogen Bonds

15.
Adenine bonds with ______________.
a)
Guanine
b)
Thymine
c)
Cytosine
d)
Adenine
16.

What is the first step in the process of DNA replication?

a)

Helicase enzymes "unzip" the DNA molecule by breaking the hydrogen bonds

b)

free nucleotides are added to the 2 original strands of DNA

c)

2 identical DNA molecules are produced

d)

1 cell divides into 2 cells

17.

What are nucleotides composed (made) of?

a)

Sugar, Phosphate, Nitrogen Base

b)

Phosphate, Adenine, Nitrogen Base

c)

Thymine, Adenine, Cytomine

d)

Phosphate, Nitrogen, Adenine

18.

Prokaryotic cells (bacteria) has

a)

one origin of replication site

b)

many origin of replication sites

19.

In DNA. what base always pairs with A?

a)

A

b)

T

c)

C

d)

G

20.

According to the Base pair rule, if a DNA molecule contains 2 cytosine's how many guanines will it contain?

a)

1500

b)

2

c)

0

d)

1000