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Worksheetsgb pathophysiology
Total questions: 10
Worksheet time: 5mins
Which of the following mechanisms is primarily involved in the formation of cholesterol gallstones?
Increased bile acid secretion
Decreased bile acid secretion
Supersaturation of bile with cholesterol
Hypersecretion of phospholipids
Gallbladder hypomotility contributes to stone formation by
Increasing bile acid production
Causing statasis of bile
Enhancing cholesterol absorption
Decreasing bilirubin levels
Which of the following components prevents cholesterol crystallization in bile?
Lecithin
Bilirubin
Albumin
Triglycerides
What is the role of bile salts in the prevention of gallstones?
They increase gallbladder wall tension
They inhibit cholesterol absorption in the intestines
They solubilize cholesterol in bile
They stimulate hepatic cholesterol synthesis
Pigment stones are primarily formed due to:
Excess dietary cholesterol
Chronic hemolysis and increased unconjugated bilirubin
High-fat diet
Increased bile salt concentration
In chronic cholecystitis, repeated episodes of inflammation can lead to:
Decreased bile secretion
Gallbladder cancer
Fibrosis and thickening of the gallbladder wall
Portal hypertension
Which hormone stimulates gallbladder contraction and bile release?
Cck
Gastrin
Peptide
Somatostatin
In acute calculous cholecystitis, the pathophysiology primarily involves:
Hematogenous spread of infection
Bile reflux into the pancreas
Obstruction of the cystic duct by a stone
Autoimmune inflammation of bile ducts
Gallstone ileus occurs due to:
Compression of the duodenum by a large stone
Gallstone-induced perforation of the common bile duct
Migration of a large stone into the intestine via a cholecystoenteric fistula
Spasm of the sphincter of Oddi
Which of the following changes is most commonly seen in the bile composition of patients with cholesterol gallstones?
Increased bile salt to cholesterol ratio
Increased lecithin levels
Increased cholesterol to bile salt ratio
Increased conjugated bilirubin
