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Minerals quiz

Total questions: 35

Worksheet time: 12mins

Name
Class
Date
1.

Which of the following is the primary form of iron absorbed in the duodenum?

a)

Ferric iron (Fe3+)

b)

Ferrous iron (Fe2+)

c)

Hemosiderin

d)

Transferrin-bound iron

2.

Which protein reduces ferric iron (Fe3+) to ferrous iron (Fe2+) at the apical membrane of enterocytes to facilitate absorption?

a)

Ferroportin

b)

Duodenal cytochrome B (DcytB)

c)

Hephaestin

d)

Transferrin

3.

Which transporter is responsible for the export of iron from enterocytes into the bloodstream?

a)

DMT1 (Divalent Metal Transporter 1)

b)

Ferroportin

c)

Transferrin receptor

d)

Hepcidin

4.

What is the primary storage form of iron in the body?

a)

Transferrin

b)

Hemosiderin

c)

Ferritin

d)

Heme

5.

Which hormone regulates iron homeostasis by binding to ferroportin and causing its internalization and degradation?

a)

Hepcidin

b)

Erythropoietin

c)

Transferrin

d)

Ferritin

6.

How much of the total body iron is typically found in hemoglobin?

a)

10-20%

b)

25-35%

c)

45-55%

d)

65-75%

7.

Which protein oxidizes ferrous iron (Fe2+) to ferric iron (Fe3+) during its transport from enterocytes into the bloodstream?

a)

Duodenal cytochrome B

b)

Hephaestin

c)

Ceruloplasmin

d)

Hemosiderin

8.

Which of the following factors enhances iron absorption from the gut?

a)

Phytates

b)

Calcium

c)

Vitamin C

d)

Polyphenols

9.

Which condition causes increased hepcidin production?

a)

Iron deficiency anemia

b)

Hemochromatosis

c)

Inflammation

10.

Which protein is responsible for transporting iron in the bloodstream?

a)

Ferritin

b)

Transferrin

c)

Hemosiderin

d)

Ferroportin

11.

What percentage of total body calcium is found in the bones?

a)

Approximately 50%

b)

Approximately 70%

c)

Approximately 90%

d)

Approximately 99%

12.

Which vitamin is required for intestinal calcium absorption?

a)

Vitamin A

b)

Vitamin C

c)

Vitamin D

d)

Vitamin K

13.

Which form of vitamin D is biologically active in calcium absorption?

a)

Cholecalciferol (Vitamin D3)

b)

Ergocalciferol (Vitamin D2)

c)

Calcidiol (25-hydroxyvitamin D)

d)

Calcitriol (1,25-dihydroxyvitamin D)

14.

Which intestinal transport protein is directly upregulated by 1,25-dihydroxyvitamin D to increase calcium absorption?

a)

TRPV5

b)

TRPV6

c)

Calbindin-D28k

d)

Na+/Ca2+ exchanger

15.

Where does most active calcium absorption occur in the gastrointestinal tract?

a)

Stomach

b)

Duodenum

c)

Ileum

d)

Colon

16.

Which hormone increases calcium reabsorption in the distal tubules of the kidney?

a)

Calcitonin

b)

Paratharmone

c)

Cortisol

d)

Aldosterone

17.

Which of the following decreases serum calcium levels?

a)

Parathyroid hormone

b)

1,25-dihydroxyvitamin D

c)

Calcitonin

d)

Low phosphate levels

18.

Which protein is responsible for calcium transport within the cytoplasm of intestinal epithelial cells during absorption?

a)

Calbindin

b)

Calmodulin

c)

TRPV6

d)

Na+/Ca2+ exchanger

19.

Which mechanism is primarily responsible for calcium efflux from intestinal epithelial cells into the bloodstream?

a)

Voltage-gated calcium channels

b)

TRPV5/6 channels

c)

Na+/Ca2+ exchanger and Ca2+-ATPase

d)

Paracellular diffusion

20.

What is the primary site of copper absorption in the gastrointestinal tract?

a)

Stomach

b)

Duodenum and proximal jejunum

21.

Which transporter is primarily responsible for copper uptake at the apical membrane of enterocytes?

a)

DMT1

b)

CTR1 (Copper transporter 1)

c)

ATP7A

d)

Ceruloplasmin

22.

Which protein is responsible for copper export from enterocytes into the bloodstream?

a)

CTR1

b)

ATP7A

c)

ATP7B

d)

Metallothionein

23.

Which protein is the primary carrier of copper in the bloodstream?

a)

Albumin

b)

Transferrin

c)

Ceruloplasmin

d)

Metallothionein

24.

What percentage of plasma copper is typically bound to ceruloplasmin?

a)

Approximately 30%

b)

Approximately 50%

25.

Which copper transport protein is defective in Wilson's disease?

a)

CTR1

b)

ATP7A

c)

ATP7B

d)

Ceruloplasmin

26.

Which of the following is NOT a copper-containing enzyme?

a)

Cytochrome c oxidase

b)

Superoxide dismutase

c)

Tyrosinase

d)

Carbonic anhydrase

27.

Which organ is the primary site for copper storage in the body?

a)

Liver

b)

Brain

c)

Kidney

d)

Pancreas

28.

Which intracellular protein binds to copper in hepatocytes to protect against copper toxicity?

a)

Ceruloplasmin

b)

Metallothionein

c)

Transferrin

d)

Ferritin

29.

What is the average daily dietary requirement of copper for adults?

a)

0.1-0.5 mg

b)

0.9-1.3 mg

c)

2.0-3.0 mg

d)

5.0-7.0 mg

30.

Which of the following hormones increases serum calcium levels?

a)

Calcitonin

b)

Parathyroid hormone

c)

Cortisol

d)

Insulin

31.

Assertion: Vitamin D deficiency can lead to hypocalcemia. Reason: Vitamin D is essential for intestinal calcium absorption.

a)

Both assertion and reason are true, and reason explains the assertion

b)

Both assertion and reason are true, but reason does not explain the assertion

c)

Assertion is true, but reason is false

d)

Assertion is false, but reason is true

32.

A 45-year-old woman presents with bone pain, muscle weakness, and fatigue. Laboratory tests show decreased serum calcium, decreased phosphate, and elevated alkaline phosphatase. The most likely diagnosis is: ____________.

a)

Osteomalacia

b)

Osteoporosis

c)

Paget's disease of bone

d)

Hyperparathyroidism

33.

Hypercalcemia crisis is most commonly managed with:

a)

Intravenous sodium bicarbonate

b)

Intravenous furosemide and normal saline

c)

Oral calcium supplements

d)

Intramuscular vitamin D

34.

Assertion: The prolonged use of proton pump inhibitors can lead to an increased risk of fractures. Reason: Proton pump inhibitors reduce calcium absorption by decreasing gastric acid secretion.

a)

Both assertion and reason are true, and reason explains the assertion

b)

Both assertion and reason are true, but reason does not explain the assertion

c)

Assertion is true, but reason is false

d)

Assertion is false, but reason is true

35.

Which of the following is NOT a cause of hypophosphatemia?

a)

Refeeding syndrome

b)

Respiratory alkalosis

c)

Vitamin D deficiency

d)

Primary hyperparathyroidism