WorksheetsMinerals quiz
Total questions: 35
Worksheet time: 12mins
Which of the following is the primary form of iron absorbed in the duodenum?
Ferric iron (Fe3+)
Ferrous iron (Fe2+)
Hemosiderin
Transferrin-bound iron
Which protein reduces ferric iron (Fe3+) to ferrous iron (Fe2+) at the apical membrane of enterocytes to facilitate absorption?
Ferroportin
Duodenal cytochrome B (DcytB)
Hephaestin
Transferrin
Which transporter is responsible for the export of iron from enterocytes into the bloodstream?
DMT1 (Divalent Metal Transporter 1)
Ferroportin
Transferrin receptor
Hepcidin
What is the primary storage form of iron in the body?
Transferrin
Hemosiderin
Ferritin
Heme
Which hormone regulates iron homeostasis by binding to ferroportin and causing its internalization and degradation?
Hepcidin
Erythropoietin
Transferrin
Ferritin
How much of the total body iron is typically found in hemoglobin?
10-20%
25-35%
45-55%
65-75%
Which protein oxidizes ferrous iron (Fe2+) to ferric iron (Fe3+) during its transport from enterocytes into the bloodstream?
Duodenal cytochrome B
Hephaestin
Ceruloplasmin
Hemosiderin
Which of the following factors enhances iron absorption from the gut?
Phytates
Calcium
Vitamin C
Polyphenols
Which condition causes increased hepcidin production?
Iron deficiency anemia
Hemochromatosis
Inflammation
Which protein is responsible for transporting iron in the bloodstream?
Ferritin
Transferrin
Hemosiderin
Ferroportin
What percentage of total body calcium is found in the bones?
Approximately 50%
Approximately 70%
Approximately 90%
Approximately 99%
Which vitamin is required for intestinal calcium absorption?
Vitamin A
Vitamin C
Vitamin D
Vitamin K
Which form of vitamin D is biologically active in calcium absorption?
Cholecalciferol (Vitamin D3)
Ergocalciferol (Vitamin D2)
Calcidiol (25-hydroxyvitamin D)
Calcitriol (1,25-dihydroxyvitamin D)
Which intestinal transport protein is directly upregulated by 1,25-dihydroxyvitamin D to increase calcium absorption?
TRPV5
TRPV6
Calbindin-D28k
Na+/Ca2+ exchanger
Where does most active calcium absorption occur in the gastrointestinal tract?
Stomach
Duodenum
Ileum
Colon
Which hormone increases calcium reabsorption in the distal tubules of the kidney?
Calcitonin
Paratharmone
Cortisol
Aldosterone
Which of the following decreases serum calcium levels?
Parathyroid hormone
1,25-dihydroxyvitamin D
Calcitonin
Low phosphate levels
Which protein is responsible for calcium transport within the cytoplasm of intestinal epithelial cells during absorption?
Calbindin
Calmodulin
TRPV6
Na+/Ca2+ exchanger
Which mechanism is primarily responsible for calcium efflux from intestinal epithelial cells into the bloodstream?
Voltage-gated calcium channels
TRPV5/6 channels
Na+/Ca2+ exchanger and Ca2+-ATPase
Paracellular diffusion
What is the primary site of copper absorption in the gastrointestinal tract?
Stomach
Duodenum and proximal jejunum
Which transporter is primarily responsible for copper uptake at the apical membrane of enterocytes?
DMT1
CTR1 (Copper transporter 1)
ATP7A
Ceruloplasmin
Which protein is responsible for copper export from enterocytes into the bloodstream?
CTR1
ATP7A
ATP7B
Metallothionein
Which protein is the primary carrier of copper in the bloodstream?
Albumin
Transferrin
Ceruloplasmin
Metallothionein
What percentage of plasma copper is typically bound to ceruloplasmin?
Approximately 30%
Approximately 50%
Which copper transport protein is defective in Wilson's disease?
CTR1
ATP7A
ATP7B
Ceruloplasmin
Which of the following is NOT a copper-containing enzyme?
Cytochrome c oxidase
Superoxide dismutase
Tyrosinase
Carbonic anhydrase
Which organ is the primary site for copper storage in the body?
Liver
Brain
Kidney
Pancreas
Which intracellular protein binds to copper in hepatocytes to protect against copper toxicity?
Ceruloplasmin
Metallothionein
Transferrin
Ferritin
What is the average daily dietary requirement of copper for adults?
0.1-0.5 mg
0.9-1.3 mg
2.0-3.0 mg
5.0-7.0 mg
Which of the following hormones increases serum calcium levels?
Calcitonin
Parathyroid hormone
Cortisol
Insulin
Assertion: Vitamin D deficiency can lead to hypocalcemia. Reason: Vitamin D is essential for intestinal calcium absorption.
Both assertion and reason are true, and reason explains the assertion
Both assertion and reason are true, but reason does not explain the assertion
Assertion is true, but reason is false
Assertion is false, but reason is true
A 45-year-old woman presents with bone pain, muscle weakness, and fatigue. Laboratory tests show decreased serum calcium, decreased phosphate, and elevated alkaline phosphatase. The most likely diagnosis is: ____________.
Osteomalacia
Osteoporosis
Paget's disease of bone
Hyperparathyroidism
Hypercalcemia crisis is most commonly managed with:
Intravenous sodium bicarbonate
Intravenous furosemide and normal saline
Oral calcium supplements
Intramuscular vitamin D
Assertion: The prolonged use of proton pump inhibitors can lead to an increased risk of fractures. Reason: Proton pump inhibitors reduce calcium absorption by decreasing gastric acid secretion.
Both assertion and reason are true, and reason explains the assertion
Both assertion and reason are true, but reason does not explain the assertion
Assertion is true, but reason is false
Assertion is false, but reason is true
Which of the following is NOT a cause of hypophosphatemia?
Refeeding syndrome
Respiratory alkalosis
Vitamin D deficiency
Primary hyperparathyroidism
