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Glycolysis and Krebs Cycle Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Which of the following is the end product of aerobic glycolysis?

a)

Lactate

b)

Pyruvate

c)

Acetyl-CoA

d)

Glucose

2.

The key regulatory enzyme of glycolysis is:

a)

Hexokinase

b)

Aldolase

c)

Phosphofructokinase-1

d)

Enolase

3.

Which of the following enzymes catalyzes the conversion of phosphoenolpyruvate to pyruvate?

a)

Aldolase

b)

Pyruvate kinase

c)

Hexokinase

d)

Enolase

4.

How many ATP molecules are net gained per glucose molecule in aerobic glycolysis?

a)

2

b)

4

c)

6

d)

8

5.

Which coenzyme is required for the glyceraldehyde-3-phosphate dehydrogenase step?

a)

NADP+

b)

FAD

c)

NAD+

d)

FMN

6.

Which of the following is an inhibitor of glycolysis?

a)

Iodoacetate

b)

Malonate

c)

Oligomycin

d)

Rotenone

7.

Fate of pyruvate under anaerobic conditions results in formation of:

a)

Acetyl-CoA

b)

Citrate

c)

Oxaloacetate

d)

Lactate

8.

Which enzyme converts pyruvate to lactate?

a)

Pyruvate carboxylase

b)

Lactate dehydrogenase

c)

Pyruvate kinase

d)

Enolase

9.

What is the net ATP yield in anaerobic glycolysis?

a)

2

b)

4

c)

6

d)

8

10.

Which hormone stimulates glycolysis?

a)

Insulin

b)

Glucagon

c)

Epinephrine

d)

Norepinephrine

11.

Where does the Krebs cycle occur in the cell?

a)

Cytosol

b)

Mitochondrial matrix

c)

Nucleus

d)

Rough ER

12.

How many NADH molecules are produced per turn of the Krebs cycle?

a)

2

b)

3

c)

4

d)

5

13.

Which enzyme catalyzes the conversion of isocitrate to alpha-ketoglutarate?

a)

Citrate synthase

b)

Isocitrate dehydrogenase

c)

Aconitase

d)

Succinyl-CoA synthetase

14.

Which of the following inhibits the Krebs cycle?

a)

Fluoroacetate

b)

Cyanide

c)

Arsenic

d)

Allopurinol

15.

How many ATP equivalents are generated from one turn of the Krebs cycle?

a)

8

b)

10

c)

12

d)

14

16.

Which compound is a key regulator of the TCA cycle?

a)

AMP

b)

NADH

c)

ATP

d)

Ca2+

17.

Which step of the Krebs cycle involves substrate-level phosphorylation?

a)

Isocitrate to alpha-ketoglutarate

b)

Alpha-ketoglutarate to succinyl-CoA

c)

Succinyl-CoA to succinate

d)

Fumarate to malate

18.

Which enzyme catalyzes the condensation of acetyl-CoA with oxaloacetate?

a)

Isocitrate dehydrogenase

b)

Succinate dehydrogenase

c)

Citrate synthase

d)

Aconitase

19.

Which is the first product formed in the Krebs cycle?

a)

Citrate

b)

Malate

c)

Fumarate

d)

Succinate

20.

The number of ATPs produced from complete oxidation of one glucose molecule via glycolysis and TCA cycle is approximately:

a)

28

b)

30

c)

36

d)

38

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