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HHB 3.8 Clinical Trials of Vaccines & Drugs

Total questions: 11

Worksheet time: 12mins

Name
Class
Date
1.

What is the purpose of clinical trials for vaccines and drugs?

a)

To increase production speed

b)

To establish safety and effectiveness

c)

To reduce manufacturing costs

d)

To improve marketing strategies

2.

What does a double-blind trial ensure in clinical studies?

a)

Only researchers know which subjects have been given the treatment

b)

Only the subjects know which participants have been given the treatment

c)

Neither subjects nor researchers know which participants have been given the treatment

d)

Both subjects and researchers know which participants have been given the treatment

3.

Why is group size important in clinical trials?

a)

To increase the cost of the trial

b)

To reduce experimental error and establish statistical significance

c)

To make the trial more complex

d)

To ensure faster results

4.

What is the role of a placebo in clinical trials?

a)

To enhance the effects of the drug

b)

To serve as a control for valid comparisons

c)

To increase the dosage of the drug

d)

To speed up the trial process

5.

How are subjects divided in clinical trials to reduce bias?

a)

By age only

b)

By gender only

c)

In a randomised way

d)

By their medical history

6.

Which description describes a Placebo controlled trial?

a)

Both groups of subjects receive the vaccine or drug.

b)

One group of subjects receives the vaccine or drug while the second group receives a placebo-control to ensure valid comparisons.

c)

Both groups of subjects receive the placebo control.

d)

One group of subjects receives the vaccine or drug while the second group receives a placebo-control to increase reliability.

7.

What is being described in the following statement?

"a 'blank' which does not contain the drug"

a)

a placebo

b)

a vaccine

c)

an adjuvant

d)

antigenic variation

8.

The design of what type of procedures must be randomised, double blind and placebo controlled?

a)

addition of adjuvants to vaccines

b)

clinical trials for vaccines & drugs

c)

mass vaccination programmes

d)

establishing
herd immunity

9.

Clinical trials for vaccines & drugs are designed with randomisation to...

a)

reduce bias

b)

ensure no one knows which group is being given the treatment

c)

include a treatment with no active ingredient

10.

Clinical trials for vaccines & drugs are designed with placebo controlled protocols to...

a)

reduce bias

b)

ensure no one knows which group is being given the treatment

c)

include a treatment with no active ingredient for comparison

11.

Clinical trials for vaccines & drugs are designed to be double-blind in order to...

a)

reduce bias

b)

ensure no one knows which group is being given the treatment

c)

include a treatment with no active ingredient for comparison