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Antitubercular drugs

Total questions: 11

Worksheet time: 7mins

Name
Class
Date
1.

The aim/s for tubercular treatment is/are

a)

to prevent recurrent.

b)

to promote drug resistance.

c)

to prevent disease transmission.

d)

to eradicate the infection.

2.

Peculiar features of mycobacterium tuberculosis includes the presence of (a)   pumps.

3.

One of the reasons Mycobacterium infections are difficult to treat is

a)

it contains thick lipid layer of its cell wall.

b)

the presence of influx pumps.

c)

its size.

d)

none of the above.

4.

Rifampicin inhibits .......subunit of RNA polymerase.

a)

alpha

b)

beta

c)

delta

d)

gamma

5.

Rifampicin is a cytochrome

a)

inhibitor.

b)

inducer.

6.

Isoniazid interferes with mycobacterial mycolic acid synthesis.

a)

TRUE

b)

FALSE

7.

Slow acetylator individuals will have lesser amount of isoniazid toxic metabolites.

a)

TRUE

b)

FALSE

8.

Isoniazid -------- metabolism of warfarin.

a)

increases

b)

reduces

9.

Pyrazinamide increase urate excretion.

a)

TRUE

b)

FALSE

10.

The use of ethambutol spares a patient for a periodic visual assessment.

a)

TRUE

b)

FALSE

11.

Choose the RIGHT statement regarding the management of tuberculosis.

a)

Intensive phase: 2 months

b)

Continuation phase: 2 months

c)

Intensive phase:4 months

d)

Continuation phase: 4 months