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DNA Fingerprinting and Gene Therapy Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

DNA fingerprinting is based on which technique?

a)

Southern blotting

b)

Western blotting

c)

Northern blotting

d)

ELISA

2.

The basis of DNA fingerprinting is?

a)

Satellite DNA

b)

RNA structure

c)

Introns

d)

Histone pattern

3.

Zymogens are also called?

a)

Hormones

b)

Inactive enzymes

c)

Substrates

d)

Coenzymes

4.

Example of a zymogen is?

a)

Trypsin

b)

Pepsinogen

c)

Amylase

d)

Lipase

5.

PCR is used for?

a)

Protein sequencing

b)

DNA amplification

c)

RNA translation

d)

Lipid analysis

6.

The enzyme used in PCR is?

a)

Taq polymerase

b)

Reverse transcriptase

c)

DNA ligase

d)

RNA polymerase

7.

Which of the following is a reverse transcriptase enzyme?

a)

Taq polymerase

b)

HIV enzyme

c)

DNA polymerase

d)

RNA polymerase

8.

Which of the following diseases is due to defect in nucleotide excision repair?

a)

Xeroderma pigmentosum

b)

Sickle cell anemia

c)

Hemophilia

d)

Phenylketonuria

9.

Which statement defines Central Dogma?

a)

DNA to RNA to Protein

b)

RNA to DNA to Protein

c)

Protein to DNA to RNA

d)

DNA to Protein to RNA

10.

Southern blotting is used for detection of?

a)

DNA

b)

RNA

c)

Proteins

d)

Lipids

11.

RFLP stands for?

a)

Random fragment length polymorphism

b)

Restricted fragment length polymorphism

c)

Rapid factor level protein

d)

Real fast linear polymer

12.

Which blotting technique is used for RNA?

a)

Northern blotting

b)

Southern blotting

c)

Western blotting

d)

Dot blotting

13.

Which one is an example of gene therapy?

a)

Insulin injection

b)

Adenosine deaminase replacement

c)

Aspirin therapy

d)

Statins

14.

The main principle behind gene therapy is?

a)

Inhibit protein

b)

RNA suppression

c)

Correct defective genes

d)

Block translation

15.

Proto-oncogenes are?

a)

Tumor suppressors

b)

Inactive oncogenes

c)

Normal genes with potential to become oncogenes

d)

Non-coding DNA

16.

An example of an oncogene is?

a)

p53

b)

Myc

c)

Cdk

d)

Rb

17.

Tumor markers are useful in?

a)

Enzyme function

b)

Liver detoxification

c)

Cancer diagnosis

d)

Hormone secretion

18.

Which of the following is a tumor marker?

a)

ALT

b)

AFP

c)

LDH

d)

Albumin

19.

PSA is a marker for?

a)

Breast cancer

b)

Liver cancer

c)

Prostate cancer

d)

Lung cancer

20.

CA-125 is a tumor marker for?

a)

Colon cancer

b)

Pancreatic cancer

c)

Ovarian cancer

d)

Prostate cancer