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WorksheetsImmunodeficiency & Hypersensitivity Quiz
Total questions: 15
Worksheet time: 8mins
Immunodeficiency disease can result from ________________.
a developmental defect of T lymphocytes.
developmental defect of bone marrow stem cells.
defect in phagocyte function.
all of the options.
Which of the following are effector cells during chronic asthma?
Macrophages and neutrophils
Mast cells and eosinophils
T cells and B cells
Natural killer cells
HIV infected CD4+ T cells may lose the expression of_________ and this leads to killing by ______.
Class II MHC, cytotoxic T cells
Class I MHC, Natural Killer cells
CD4, neutrophils
CD8, macrophages
What is/are the cardinal symptom(s) of immunodeficiency?
Chronic diarrhea
Chronic or recurrent severe infections
Poor response to treatment of infections
All of the options
Which of the following statements on severe combined immune deficiency (SCID) is FALSE?
Patients do not have functional T cells
Patients do not have functional B cells.
Patients are suffering from a secondary immunodeficiency
Patients tend to have recurrent infection.
Type III hypersensitivity is also known as ________________.
Allergy
Cytotoxic hypersensitivity
Immune complex reaction
Delayed-type hypersensitivity.
Acquired Immunodeficiency Syndrome (AIDS) is caused by a retrovirus that preferentially infects and kills _______ cells.
helper T
cytotoxic T
NK
Monocytic
Which of the following is more likely a cause of secondary immunodeficiency?
Wiskott-Aldrich Syndrome
Immunosuppressive drug taken by organ transplant recipients
MHC class II deficiency
Severe combined immunodeficiency
______________hypersensitivity is known as delayed type hypersensitivity, whereas _____________ hypersensitivity is known as immediate hypersensitivity.
Type II; Type IV
Type IV; Type I
Type III; Type I
Type I; Type IV
The presence of __________ and _______ are associated with Type III hypersensitivity reactions.
basophils; mast cells
antibodies; complement
eosinophils; cytokines
T-cells; interleukins
Which one of the following is NOT the cause of secondary immunodeficiency?
Genetic defects in phagocyte functions
Metabolic diseases
Age extremes
Malnutrition
Anaphylaxis can be triggered by IgE antibodies binding to receptors on _________.
Mast cells
B lymphocytes
T lymphocytes
Red blood cells
People allergic to peanuts develop more severe symptoms over subsequent exposures. The reason is because ____.
allergens induce tolerance in B cells
Plasma B cells become activated to produce more IgG
More allergen-antibody complexes are formed
Class switching results in more IgE being made during secondary immune responses
Which of the following is/are consequence(s) of mast cell activation during an asthma attack?
Internal bleeding
Airway obstruction
Diarrhoea
All of the options
The transfusion of mismatched blood from donor to recipient will result in _________ hypersensitivity.
Type I
Type II
Type III
Type IV
