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Neurotransmitters and Muscle Physiology Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

What is the neurotransmitter released at the neuromuscular junction?

a)

Dopamine

b)

Acetylcholine

c)

Norepinephrine

d)

GABA

2.

Which ion is essential for release of neurotransmitter at NMJ?

a)

Sodium

b)

Potassium

c)

Calcium

d)

Chloride

3.

Which enzyme breaks down acetylcholine in the synaptic cleft?

a)

Choline acetyltransferase

b)

Acetylcholinesterase

c)

Monoamine oxidase

d)

Tyrosine hydroxylase

4.

Myasthenia gravis is caused by antibodies against?

a)

Voltage-gated calcium channels

b)

Muscle actin

c)

Acetylcholine receptors

d)

Dopamine receptors

5.

Which drug is used to diagnose myasthenia gravis?

a)

Physostigmine

b)

Edrophonium

c)

Atropine

d)

Neostigmine

6.

Which type of muscle shows plateau phase in action potential?

a)

Skeletal muscle

b)

Cardiac muscle

c)

Smooth muscle

d)

All of the above

7.

Motor unit is defined as?

a)

Motor neuron + sensory neuron

b)

Sensory neuron + muscle fibers

c)

Single motor neuron + all muscle fibers it innervates

d)

All muscle fibers in one muscle

8.

Rigor mortis occurs due to depletion of which substance?

a)

Calcium

b)

ATP

c)

Sodium

d)

Potassium

9.

Which protein masks the myosin binding site on actin in resting muscle?

a)

Tropomyosin

b)

Actin

c)

Troponin

d)

Myosin

10.

Which type of muscle contraction occurs without change in length?

a)

Isometric

b)

Isotonic

c)

Isokinetic

d)

Concentric

11.

Troponin complex is present in?

a)

Skeletal muscle only

b)

Cardiac muscle only

c)

Smooth muscle only

d)

Skeletal and cardiac muscle

12.

Which ion binds to troponin to initiate muscle contraction?

a)

Magnesium

b)

Potassium

c)

Calcium

d)

Sodium

13.

In skeletal muscle, calcium is released from?

a)

Mitochondria

b)

Sarcolemma

c)

Nucleus

d)

Sarcoplasmic reticulum

14.

End plate potential is a type of?

a)

Action potential

b)

Graded potential

c)

Resting potential

d)

Hyperpolarization

15.

Resting membrane potential of skeletal muscle is approximately?

a)

-40 mV

b)

-55 mV

c)

-70 mV

d)

-90 mV

16.

Muscle tone is mainly maintained by?

a)

Cerebellum

b)

Alpha motor neurons

c)

Gamma motor neurons

d)

Motor cortex

17.

Which is not a feature of smooth muscle?

a)

Spindle-shaped cells

b)

Presence of sarcomere

c)

Involuntary control

d)

Single nucleus per cell

18.

Which receptor is involved in excitation-contraction coupling in skeletal muscle?

a)

Nicotinic receptor

b)

Ryanodine receptor

c)

Muscarinic receptor

d)

DHP receptor

19.

T-tubules are best developed in which type of muscle?

a)

Smooth muscle

b)

Skeletal muscle

c)

Cardiac muscle

d)

All equally

20.

Which of the following is a depolarizing neuromuscular blocker?

a)

Atracurium

b)

Succinylcholine

c)

Curare

d)

Neostigmine