WorksheetsCardio ER
Total questions: 70
Worksheet time: 35mins
A 54-year-old male presents with sudden, severe chest pain radiating to the back. The pain began abruptly while lifting boxes. BP is 180/100 in the right arm and 145/90 in the left arm. What is the most likely diagnosis?
STEMI
Pulmonary embolism
Aortic dissection
GERD
Pericarditis
Which of the following chest pain characteristics is most consistent with pericarditis?
Worse with exertion and relieved with rest
Sudden onset, tearing, radiates to back
Worse when lying flat, improved when leaning forward
Associated with hemoptysis and dyspnea
Constant, pressure-like pain with diaphoresis
A patient presents with pleuritic chest pain and shortness of breath after a long flight. Vitals: HR 112, RR 24, SpO₂ 89% on RA. What is the best next step?
Administer aspirin
Obtain CTA chest
Perform stress ECG
Start nitroglycerin drip
Order abdominal ultrasound
Which is most associated with stable angina?
Chest pain at rest
Chest pain lasting >30 minutes
Relieved with nitroglycerin and rest
Elevated troponin
Worsening pattern over days
Which of the following causes of chest pain is most likely to present with a widened mediastinum on chest X-ray?
STEMI
Pulmonary embolism
Pneumothorax
Aortic dissection
Costochondritis
A 61-year-old man presents with crushing chest pain radiating to the left arm and jaw for the past 30 minutes. He is diaphoretic and nauseated. ECG shows ST elevations in leads V2–V5. What is the most appropriate next step?
Begin metoprolol and schedule stress test
Administer tPA and send to cath lab next day
Administer aspirin and sublingual nitroglycerin, then activate cath lab
Perform echocardiogram before deciding treatment
Order CT chest to rule out dissection
What ECG finding is most diagnostic for STEMI?
PR segment depression
ST elevation ≥1 mm in two contiguous leads
ST depression and T wave inversion
Q waves in inferior leads
Peaked T waves
Which of the following best describes the pathophysiology of a STEMI?
Coronary vasospasm causing temporary ischemia
Subendocardial ischemia due to supply-demand mismatch
Complete coronary artery occlusion causing transmural infarction
Plaque erosion causing transient platelet aggregation
Microvascular embolization without necrosis
A patient with suspected MI has normal ECG and initial troponin. What is the best next step?
Rule out MI and discharge
Repeat troponin in 6 hours only
Observe and trend high-sensitivity troponins q2h
Administer thrombolytics
Schedule outpatient echocardiogram
Which medication is not routinely given during acute MI management?
A. Aspirin
B. P2Y12 inhibitor (e.g., clopidogrel)
C. Beta-blocker
D. Proton pump inhibitor
E. Heparin
A 72-year-old man presents after a syncopal episode while standing in church. He felt lightheaded and then collapsed. Vitals are normal and EKG shows sinus bradycardia with a first-degree AV block. Which of the following is the most likely cause of his syncope?
Vasovagal syncope
Orthostatic hypotension
Cardiac arrhythmia
Hypoglycemia
Pulmonary embolism
Which feature on history most strongly suggests a cardiac cause of syncope?
Occurs with prolonged standing
Associated with nausea and warmth beforehand
Occurs suddenly without warning during exertion
Associated with emotional stress
Triggered by pain or blood draw
A patient with syncope has this ECG: P waves and QRS complexes occur independently. The ventricular rate is 30 bpm. What is the appropriate next step?
Observation
Atropine trial and discharge
Transcutaneous pacing and admit for pacemaker
Cardioversion
Beta-blocker administration
A 26-year-old healthy woman faints while getting her blood drawn. She felt warm and nauseated beforehand. What is the most appropriate management?
Send for head CT
Place on telemetry
Rehydrate, observe briefly, and reassure
Start metoprolol
Refer for tilt table testing
Which diagnostic test is most appropriate for initial evaluation of syncope in the ED?
Tilt table testing
Holter monitor
Brain MRI
ECG
Echocardiogram
A 70-year-old man presents with worsening dyspnea, orthopnea, and bilateral lower extremity edema. He has an S3 gallop and crackles at the lung bases. BNP is elevated. What is the most appropriate next step?
Oral beta-blocker and discharge
Immediate IV furosemide
IV steroids and albuterol
Subcutaneous heparin
Oral amiodarone
Which of the following is most characteristic of left-sided heart failure?
Jugular venous distension and ascites
Worsening with lying flat and paroxysmal nocturnal dyspnea
Pulsatile liver and ankle swelling
Normal breath sounds but elevated BNP
Polycythemia and hemoptysis
Which lab value is most helpful in supporting a diagnosis of acute decompensated heart failure in the emergency department?
Troponin
Serum lactate
Creatinine kinase
B-type natriuretic peptide (BNP)
D-dimer
Which of the following is the most common cause of CHF in the United States?
Valvular disease
Viral myocarditis
Ischemic heart disease
Hypertrophic cardiomyopathy
Thyroid disease
A 68-year-old woman presents with acute dyspnea, orthopnea, and pink frothy sputum. She has bilateral crackles, an S3 gallop, and elevated jugular venous pressure. CXR shows bilateral perihilar opacities. What is the most appropriate initial management?
Albuterol and corticosteroids
IV furosemide and nitroglycerin
Oral lisinopril and discharge
Broad-spectrum antibiotics
Emergent intubation and tPA
What is the most likely cause of pulmonary edema in a patient with left-sided heart failure?
Increased pulmonary capillary hydrostatic pressure
Decreased oncotic pressure
Lymphatic obstruction
Capillary leak from infection
Aspiration of gastric contents
Which physical exam finding is most specific for cardiogenic pulmonary edema?
Inspiratory wheezing
Dullness to percussion
Basilar crackles and S3 gallop
Whispered pectoriloquy
Asymmetric breath sounds
What is the most appropriate imaging study to determine ejection fraction and evaluate structural causes of heart failure?
Chest X-ray
Cardiac CT
Transthoracic echocardiogram
MRI
Right heart catheterization
A 75-year-old male with known systolic CHF presents with shortness of breath and O2 saturation of 88% on room air. Chest X-ray shows cardiomegaly and Kerley B lines. BNP is elevated. Which of the following is not appropriate in the acute setting?
Oxygen supplementation
Loop diuretics
Sublingual nitroglycerin
IV labetalol
Noninvasive ventilation (BiPAP) if needed
Which chest X-ray finding is most consistent with pulmonary edema due to heart failure?
Hyperinflation with flattened diaphragms
Mediastinal shift
Bilateral perihilar infiltrates with Kerley B lines
Large pleural effusion on one side
Ground-glass opacities without cardiomegaly
A 64-year-old man presents with chest tightness that occurs when climbing stairs and is relieved with rest. ECG is normal, and troponins are negative. What is the most likely diagnosis?
STEMI
Unstable angina
Stable angina
Variant (Prinzmetal) angina
GERD
Which of the following is true regarding unstable angina?
Pain is relieved consistently with rest and nitroglycerin
There is complete occlusion of a coronary artery
Troponins are typically elevated
There is no myocardial necrosis, but symptoms are new or worsening
It is usually provoked only by exertion
Which of the following medications is not part of the acute ED treatment for unstable angina?
A. Aspirin
B. Clopidogrel
C. IV furosemide
D. Nitroglycerin
E. Beta-blockers
What is the first-line outpatient diagnostic study to evaluate a patient with stable angina and normal baseline ECG?
Coronary CTA
Cardiac catheterization
Stress ECG
Chest X-ray
Troponin I
A patient with stable angina and no contraindications is being discharged from the ED. Which of the following is an appropriate long-term medication regimen?
A. Aspirin, beta-blocker, statin, sublingual nitroglycerin
B. Heparin, tPA, PPI
C. Dual antiplatelet therapy, IV nitroglycerin, morphine
D. Amiodarone, lisinopril, metformin
E. Digoxin, warfarin, statin
A 71-year-old man presents with sudden-onset pain in the left leg. On exam, the leg is pale, pulseless, cold to touch, and the patient reports numbness. What is the next best step?
Elevate the leg and apply warm compresses
Start IV heparin and consult vascular surgery
Order Doppler in the morning and monitor pulses
Begin aspirin and statin and discharge
Initiate thrombolytics in the emergency department without imaging
Which of the following is one of the 6 P’s of acute limb ischemia?
Pallor
Pruritus
Petechiae
Pulsus paradoxus
Pitting edema
Which of the following is most likely a cause of embolic acute limb ischemia?
Arterial dissection
Deep vein thrombosis
Atrial fibrillation
Atherosclerotic plaque rupture
Smoking
A bedside Doppler reveals absent arterial signals in the foot. What additional test should be ordered immediately if neurologic deficits are present?
ABI
CT angiography of lower extremity
MRI
D-dimer
Stress test
What is the primary goal of treatment in acute arterial occlusion of the limb?
Manage pain and inflammation
Delay surgery to allow thrombolytics to work
Restore perfusion within 6 hours to prevent irreversible damage
Reduce clot burden with aspirin alone
Control blood pressure and cholesterol
A 72-year-old man with a history of hypertension presents with acute dyspnea, chest pain, and a new harsh systolic murmur radiating to the carotids. He becomes hypotensive and syncopal. Which valvular emergency is most likely?
Mitral regurgitation
Aortic stenosis
Mitral stenosis
Tricuspid regurgitation
Aortic regurgitation
Which of the following cardiomyopathies is most commonly associated with sudden cardiac death in young athletes?
Dilated cardiomyopathy
Restrictive cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy
Hypertrophic cardiomyopathy
Takotsubo cardiomyopathy
What is the most appropriate initial management for a patient with hypertrophic cardiomyopathy who presents with exertional chest pain and syncope?
Diuretics and IV fluids
Beta-blockers and avoid dehydration
Thrombolytics and aspirin
Cardioversion
ACE inhibitors and nitrates
A patient with suspected acute mitral regurgitation after an inferior MI develops respiratory distress. On exam, there is a holosystolic murmur at the apex radiating to the axilla and bibasilar crackles. What is the best next step?
IV diuretics and discharge
Begin high-dose steroids
Emergent echocardiogram and cardiothoracic consult
Administer adenosine
Prescribe long-acting nitrates
Which of the following is true regarding dilated cardiomyopathy?
Most often caused by genetic sarcomere mutations
Leads to reduced ejection fraction and systolic dysfunction
Characterized by concentric hypertrophy and preserved EF
Manifests with bradycardia and AV block only
Always requires emergent valve surgery
A 42-year-old woman presents with sudden-onset dyspnea and pleuritic chest pain 4 days after returning from a transatlantic flight. She is tachycardic and has an oxygen saturation of 91% on room air. What is the most appropriate next diagnostic step?
Chest X-ray
Troponin and ECG
CT pulmonary angiography (CTA)
Echocardiogram
D-dimer only
Which of the following is a major risk factor for pulmonary embolism?
Chronic asthma
Prolonged immobility
Diabetic ketoacidosis
Smoking marijuana
Iron-deficiency anemia
Which of the following is the most common presenting symptom of pulmonary embolism?
Hemoptysis
Syncope
Pleuritic chest pain
Sudden-onset dyspnea
Fever
What is the initial treatment of a hemodynamically stable patient with confirmed pulmonary embolism and no contraindications?
Oral warfarin only
IV thrombolytics
Subcutaneous low molecular weight heparin or DOAC
Aspirin and clopidogrel
Oxygen and steroids
A patient with PE becomes hypotensive, tachycardic, and hypoxic despite oxygen therapy. What is the next best step in management?
Administer IV steroids
Intubate and observe
Begin IV tPA (thrombolytics)
Start aspirin and repeat CTA
Begin diuretics
A 55-year-old man presents to the ED with a BP of 240/130 mmHg and a complaint of blurry vision and a severe headache. Fundoscopy reveals papilledema. What is the goal of BP reduction in the first hour?
Normalize BP to <120/80 mmHg
Lower BP to <160/100 mmHg immediately
Reduce MAP by no more than 25% in the first hour
Reduce systolic BP to <100 mmHg
Delay BP treatment for 24 hours
Which of the following defines a hypertensive emergency?
BP > 140/90 with headache
BP > 180/120 with no symptoms
BP > 180/120 with evidence of target-organ damage
BP > 160/100 that resolves with rest
BP > 200/100 with family history of hypertension
Which of the following IV medications is most appropriate for acute blood pressure control in hypertensive encephalopathy?
IV metoprolol
IV nicardipine
IV furosemide
IV lisinopril
IV hydralazine
A 32-year-old pregnant woman at 36 weeks presents with a BP of 190/120, headache, and 3+ proteinuria. What is the most appropriate initial agent for BP control?
IV nitroglycerin
IV labetalol
IV nicardipine
Oral atenolol
IV nitroprusside
Which of the following is true regarding hypertensive urgency?
Requires admission for IV medication
Defined by BP >180/120 with neurologic symptoms
No evidence of end-organ damage
Requires MAP reduction of 50% in 1 hour
Treated with IV labetalol and nicardipine
A 67-year-old man with hypertension presents with sudden-onset "tearing" chest pain radiating to his back. On exam, his right arm BP is 190/110 and his left is 160/90. CXR shows a widened mediastinum. What is the best next step in diagnosis?
Chest X-ray only
Cardiac enzymes and ECG
CT angiography of chest and abdomen
Pulmonary angiogram
Echocardiogram only
Which of the following is true regarding aortic dissection?
Always causes hypotension
Type A dissections are managed medically only
Dissections are most often caused by trauma
Beta-blockers should be used before vasodilators
D-dimer is diagnostic
What is the initial treatment goal for a stable ascending aortic dissection (Type A)?
Immediate IV fluids and inotropes
Maintain SBP >160 mmHg for perfusion
HR <60 bpm and SBP 100–120 mmHg with beta-blockers ± nitroprusside
Start oral antihypertensives and refer to vascular surgery
Start aspirin and high-dose statin
Which of the following is an indication for elective repair of an asymptomatic abdominal aortic aneurysm (AAA)?
Diameter >3.0 cm
Diameter ≥5.5 cm in men or growth >0.5 cm in 6 months
Presence of bruit over aorta
BP >160/100 despite medications
Any aneurysm found on screening ultrasound
A 75-year-old man with a known AAA presents with sudden flank pain, hypotension, and a pulsatile abdominal mass. What is the immediate next step?
Stat CT angiogram
IV beta-blockers and observation
Bedside ultrasound and emergent vascular surgery consult
Start broad-spectrum antibiotics
Monitor serial abdominal exams
A 68-year-old male smoker presents with chronic calf pain while walking that resolves with rest. He has diminished dorsalis pedis pulses. What is the most likely diagnosis?
Deep vein thrombosis
Chronic venous insufficiency
Acute limb ischemia
Peripheral arterial disease (PAD)
Cellulitis
Which of the following is the most significant modifiable risk factor for peripheral vascular disease?
Hypertension
Diabetes mellitus
Hyperlipidemia
Smoking
Advanced age
Which of the following is the first-line diagnostic test to assess the severity of chronic arterial insufficiency in a patient with claudication?
CT angiography
Venous duplex ultrasound
Ankle-brachial index (ABI)
Cardiac catheterization
MRI of lower extremities
A patient with PAD is unable to walk more than a block without significant leg pain. What is the first-line pharmacologic therapy to improve symptoms?
Cilostazol
Atorvastatin
Aspirin
Lisinopril
Clopidogrel
Which of the following is true about venous insufficiency as compared to arterial disease?
More commonly causes claudication
Ulcers are typically located on toes
Pain improves with elevation of legs
Pulses are absent
Skin is cool and hairless
A 28-year-old woman presents with palpitations. ECG shows a narrow complex tachycardia at 180 bpm with no visible P waves. She is alert and hemodynamically stable. What is the first-line treatment?
Amiodarone
IV diltiazem
Synchronized cardioversion
Vagal maneuvers followed by IV adenosine
IV metoprolol
A patient presents with palpitations and irregularly irregular rhythm. ECG shows absence of P waves and variable R-R intervals. What is the initial treatment if the patient is stable and in A-fib with rapid ventricular response?
Synchronized cardioversion
IV furosemide
IV diltiazem or metoprolol
Adenosine
Lidocaine
A 68-year-old man collapses at home. EMS finds him pulseless with the monitor showing polymorphic ventricular tachycardia (“twisting of the points”). What is the first-line treatment?
IV amiodarone
IV magnesium sulfate
IV calcium gluconate
IV adenosine
Lidocaine
A 72-year-old man has bradycardia with a HR of 28 bpm. ECG shows complete AV dissociation with wide QRS complexes. BP is 80/40. What is the next best step?
Atropine
Transcutaneous pacing
Adenosine
Observation
Diltiazem
A patient is found unresponsive and pulseless. ECG monitor shows organized electrical activity with no palpable pulse. What is the appropriate management?
Defibrillation
Atropine
Synchronized cardioversion
High-quality CPR and epinephrine
Adenosine
A 48-year-old man presents with chest pressure lasting 15 minutes while walking. It resolved with rest. ECG: Nonspecific ST changes, Troponin: Normal, History: Moderate suspicion for ACS, Risk factors: Smoker, HTN. What is his HEART score?
2
3
4
5
6
Based on the previous patient's HEART score of 5, what is the best next step in management?
Discharge with primary care follow-up
Admit for serial troponins and consider stress testing
Immediate PCI
Thrombolytic therapy
Cardiology follow-up in 1 week
Which component of the HEART score is scored 2 points if the patient has new ST-segment depression?
A. History
B. ECG
C. Age
D. Risk factors
E. Troponin
A 65-year-old woman presents with chest pain at rest. • ECG: Normal • Troponin: Elevated • Risk factors: HTN, diabetes, hyperlipidemia, smoking What is her HEART score?
3
4
5
7
9
For patients with a HEART score of 0–3, what is the recommended disposition?
Cardiology consult and hospital admission
PCI within 24 hours
Stress testing in the ED
Safe for discharge with primary care or cardiology follow-up
Administer tPA and repeat troponin
