Worksheetsphysical pharmacy quiz lec 2,3,4
Total questions: 40
Worksheet time: 1hrs 28mins
One of that is Fundamental Properties
Density
Packing geometry
Porosity
shape
The size of a spherical particle can be expressed in terms of its
Diameter
equivalent spherical diameters
Write the scientific term
It is the science and technology of
small particles.
most pharmaceutical powders are
monosized
polydisperse
This refer to
Positive
Negative
Bimodal
Symmetric
There many factors affect on particle shape
Write 3 of there
Surface area determination methods
Large particles good adsorbents(For adsorption of gases and solutes)
True
False
" z " refer to
Open
intraparticulate voids
Closed
Intraparticulate voids
Interparticulate voids
Total volume occupied by entire powder excluding voids
Bulk volume
True volume
Voids volume
Helium is a nonadsorbing gas that penetrates smallest pores.
True
False
Flow properties of solids have great impact on
Weight and content uniformity
Mixing of powders.
Tableting process
All of that
Hausner’s ratio > 1.25
Good flow
Low flow
Flow activators (glidants) improve the
flowability by reducing adhesion and cohesion
Write what you know of that.
Improvement of flow property
Write 3 of that
Force applied per
unit area to make liquid flow or solid
deformation (F/A)
Shear rate
Shear
Shear stress
Write the scientific term
Change in velocity (dv), between two layers
of liquid separated by distance X (dv/ dx)
Viscosity unit
dyne. Sec/ cm2
dyne. Minute / cm2
dyne. Sec/ cm3
dyne. Minute / cm3
In Newtonian Fluids the Viscosity .............. with shear rate
Change - constant
Not change - constant
No change - not constant
Change - no constant
is a plot of shear rate (G) as a function of shear stress (F)
Viscogram
Rheogram
(shear thinning)
Plastic
Pseudoplastic
Dilatant
In visco gram
Viscosity is decrease with shear except
Plastic
Pseudoplastic
Dilatant
In Rheogram
Slope=Mobility
Plastic
Pseudoplastic
Dilatant
Write the scientific writing
It is the minimum shear stress (force) that required by the system before it
begins to flow and to convert it to a Newtonian System (linear relationship
between F & G).
Whipping
cream
Plastic
Pseudoplastic
Dilatant
(Ketchup)
Plastic
Pseudoplastic
Dilatant
At shear stress < Yield value
àbehave as Newtonian systems.
behave as elastic solids exhibiting reversible
deformation,
Time independent rheological behavior
Hysteresis loop
Superimposing
In Time-Dependent Non-Newtonian Flow
it was assumed that the system adapts itself to changing
shear instantaneously (so Fast) àà Single curve at
increasing or decreasing shear rates.
True
False
Gel -------> soln -------> gel
Made by fast proccess
Thixotropy
Rheopexy
It is isothermal and comparatively slow recovery on
standing of materials lost their consistency with shearing
Thixorropy
Rheopexy
Bentonite sodium (.......w/w) gel
2
4
6
8
Viscosity............with duration of shearing
Increase
Decrease
Not change
Importance of rheology (In pharmacy)
Write 3 of there
Kinematic
Viscosity unit
Stoke
dyne. Sec/ cm2
based on velocity of a falling object through a liquid under
gravity
Capillary
viscometer
Density-dependent
viscometer
Rotational
viscometer
Cup & bob viscometer
Multipoint instruments
One-point instruments
One-point instruments suitable for Newtonian fluids only
True
False
In Time-independent system
Thixotropy , Rheopexy
True
False
Example of Newtonian Fluids Water, alcohol, syrup, glycerin
True
False
