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final

Total questions: 100

Worksheet time: 50mins

Name
Class
Date
1.

a cohort study differs from a case-control study in that:

a)

subjects are enrolled or categorized on the basis of their exposure status in a cohort study but not in a case control study

b)

cohort studies require many years to conduct, but case-control studies do not

c)

cohort studies are conducted to investigate chronic diseases, case-control studies are used for infectious diseases

d)

subjects are asked about their exposure status in a cohort study but not in a case-control study

2.

what is 'selection bias' in epidemiological research?

a)

bias that occurs due to confounding factors affecting research outcomes

b)

bias that arises because the research is conducted by less-experienced researchers

c)

bias that arises when the research sample does not represent the entire population

d)

bias that occurs due to a cause-and-effect relationship between independent variables

3.

in one class there are 10 male and 20 female get dengue fever. what is the ratio of female to get dengue fever?

a)

3/7

b)

2/3

c)

1/2

d)

2/10

e)

2/1

4.

which of the following is an example of a vector-borne disease

a)

malaria

b)

hiv/aids

c)

influenza

d)

diabetes

5.

can you always tell if someone has covid-19

a)

yes. you can tell just by where a person comes from, their race and ethnicity

b)

yes-it will be obvious, a person with covid-19 coughs a lot

c)

no-not everyone with covid-19 has symptoms

6.

when the participants in behavioral studies change their behavior or performance in response to being observed

a)

selection bias

b)

hawthorne bias

c)

confounding

7.

_ is a non-causal association between an exposure and outcome due to the influence of a third variable

a)

selection bias

b)

interaction

c)

information bias

d)

confounding

8.

which of the following are goals of vaccination?

a)

prevent infection

b)

prevent disease

c)

prevent transmission

d)

all of the above

9.

john snow's investigation of cholera is considered a model for epidemiologic field investigation because it included a:

a)

comparison of a health outcome among exposed and unexposed groups

b)

using microscope to prove the vibrio cholera

10.

the occurrence of new disease or mortality within a defined period of observation in a specific population is

a)

incidence

b)

prevalence

11.

obtaining information about exposures that occurred in the future is considered

a)

ecological fallacy

b)

prospective approach

c)

retrospective approach

12.

in january, there were 50 cases of malaria diagnosed in district x, which has a population of 200,000. of these, 30 were in males and 20 were in females. what is the proportion if the cases were in females?

a)

20/50

b)

30/200,000

c)

50/200,000

d)

30/50

13.

the implementation of health education programs is an example of:

a)

tertiary prevention

b)

secondary prevention

c)

primary prevention

14.

reducing the impact of disease/complication

a)

primary prevention

b)

tertiary prevention

c)

secondary prevention

d)

cheapest prevention

15.

there may be a spurious association between diseases or between a characterized disease because of the different probabilities of admission to a hospital for those with the disease, without the disease and with the characteristic of interest

a)

berksonian bias

b)

measurement bias

c)

information bias

16.

Residence of three villages with three different types of water supply were asked to participate in a survey to identify cholera carriers. Because several cholera deaths had occurred recently, virtually everyone present at the time underwent examination. The proportion of residents in each village who were carriers was computed and compared. What is the proper classification for this study?

a)

Nonconcurrent/Retrospective cohort study

b)

Concurrent/Prospective cohort study

c)

Cross-sectional study

d)

Experimental study

17.

Those who agree to be in a study may be in some way different from those who refuse to participate (......)

a)

Chance

b)

Confounding

c)

Reverse Time Order

d)

Bias

e)

Causal

18.

Tertiary prevention is intended to reduce the duration and severity of disease.

a)

False

b)

True

19.

All of the following are important criteria when making causal inferences except

a)

Strength of association

b)

Consistency with existing knowledge

c)

Predictive value

d)

Consistency of association in several studies

e)

Dose-response relationship

20.

in a case-control study of the relationship between a cholesterol lowering drug and the risk of developing breast cancer, control subjects are sampled from participants in health screening fair. this is the type of error?

a)

confounding

b)

reverse time order

c)

selection bias

d)

misclassification

21.

reliability can be defined as:

a)

the degree to which results are consistent

b)

ensuring that patients all take a test under the same conditions

c)

the degree to which an instrument measures what it is supposed to measure

d)

concerned with measuring the frequency of new cases with reliability

e)

a measure of degree of strength of association between two variables

22.

Mammography screening (screening for breast cancer) for women age more than 40 years old

a)

Secure prevention

b)

Primary prevention

c)

Secondary prevention

d)

Cheapest prevention

e)

Tertiary prevention

23.

What is the primary purpose of a randomized controlled trial (RCT) in epidemiology?

a)

To determine the prevalence of a disease in a population

b)

To study historical trends in disease incidence

c)

To conduct interviews with cases and controls

d)

To establish cause-and-effect relationships between exposures and outcomes

24.

A large population is surveyed to determine the prevalence of this newly recognized disease by age, gender, and ethnicity

a)

Descriptive Study

b)

Case control

c)

Experimental Study

d)

Cohort

25.

The Most Expensive of Prevention

a)

Tertiary prevention

b)

Primary prevention

c)

Secondary prevention

d)

Cheapest prevention

26.

This stage of prevention is intended to reduce complications and disabilities.

a)

primary prevention

b)

secondary prevention

c)

tertiary prevention

27.

In a small pilot study, 12 women with endometrial cancer (cancer of the uterus.....) women with no apparent disease were contacted and asked whetherthey nau ever usen estrogen. Each woman with cancer was matched by age, race, weight, and parity to a woman without disease. What kind of study design is this?

a)

Concurrent/Prospective cohort

b)

Cross-sectional

c)

Retrospective cohort t

d)

Case-Control

e)

Experimental

28.

The proportion of people with the disease whose father has the disease is compared with control the corresponding proportion for people without the disease

a)

Cross sectional

b)

Experimental Study

c)

Cohort

d)

Case control

29.

An association between two variables can be:

a)

Only Positive

b)

Only Negative

c)

Either Positive or Negative

30.

In 1796, Edward Jenner gave smallpox vaccine for kids to prevent the smallpox

a)

Primary prevention

b)

Cheapest prevention

c)

Tertiary prevention

d)

Secondary prevention

31.

This criterion specifies that one must observe the cause before the effect:

a)

Plausibility

b)

Biological Gradient

c)

Temporality

32.

To assess the association between Kawasaki syndrome (KS) and carpet shampoо, investigators conducted a case-control study with 100 cases (children with KS) and 100 controls (children without KS). Among the children with KS, 50 had a history of recent exposure to carpet shampoo. Among the controls, the number with a recent history of exposure to carpet shampoo was 25. For this study, the odds ratio was:

a)

3.0

b)

0.3

c)

1.1

d)

2

33.

The indicator for measures of the strength of an association.

a)

Consistency of previous study

b)

Relative Risk

c)

Reliability

d)

Dose Response

34.

What is the primary goal of epidemiology?

a)

To prevent and control diseases in populations

b)

To promote healthy lifestyles

35.

Which of the following is NOT an analytic study design?

a)

Cohort

b)

Experimental Study

c)

Case Control

d)

Descriptive study

36.

Race and socioeconomic status are examples of:

a)

Person Variables

b)

Secular Trends

c)

Clustering

37.

Which of the following is NOT an advantage of a prospective cohort study?

a)

Recall bias is minimized compared with a case-control study

b)

Many disease outcomes can be studied simultaneously

c)

Incidence rates can be calculated

d)

Price measurement of exposure is possible

e)

It is usually costs less than a case control study

38.

What is the main goal of primary prevention?

a)

To prevent diseases from occurring in the first place

b)

To provide rehabilitation services

c)

To identify and treat diseases early

d)

To reduce the impact of an existing disease

39.

An investigator assigns a specific exposure (a new formulation of a common medication) to some participants but assigns a different exposure (the original formulation of the medication) to others. During the study period, the investigator follows both groups to determine whether the new formulation works better and/or has fewer side effects. What type of study design is this?

a)

Cross Sectional

b)

Case Control

c)

Cohort

d)

Experimental Study

40.

A Single Exposure should cause a single disease

a)

Dose Response

b)

Temporarily

c)

Plausibility

d)

Strength of Association

e)

Specificity

41.

Researchers investigated the relationship between the use of statins and p mortality by examining the records of patients who died from prostate cancer as well as records of matched controls. They report an odds ratio of 1.49 (95% confidence interval, 1.34-1.70 (P Value<0.0001). What can you conclude from these results?

a)

Statins significantly lower the risk of death from prostate cancer

b)

Statins have no effect on cancer mortality

c)

Statins do not significantly lower the risk of death from prostate cancer

d)

Statins do not significantly increase the risk of death from prostate cancer

e)

Statins significantly increase the risk of death from prostate cancer

42.

Race and socioeconomic status are examples of:

a)

Person Variables

b)

Clustering

c)

Secular Trends

43.

The relative risk and the odds ratio are important measures of the strength of an association

a)

false

b)

true

44.

Aim of Descriptive Epidemiology:

a)

Explain WHY the Risk Factors and Causal of Disease

b)

Describe the Distribution of Disease based on Person Place and Time

c)

Estimate/predict the Disease outcome

d)

Give the recomendation how to control disease

45.

A case-control study is characterized by al of the following except:

a)

Definition of cases may be difficult

b)

It is relatively inexpensive compared with most other epidemiologic study designs

c)

Incidence rates may be computed directly

d)

Patients with the disease (cases) are compared with persons without the disease (control)

e)

Assessment of past exposure may be biased

46.

Which of the following is an example of a type of descriptive epidemiologic study?

a)

Case Reports

b)

Case-Control Study

c)

Cohort Study

47.

Now, covid-19 has become:

a)

Pandemic Disease

b)

Epidemic Disease

c)

Endemic Disease

48.

A study in which children are randomly assigned to receive either a newly formulated vaccine or the currently available vaccine, and are followed to monitor for side effects and effectiveness of each vaccine, is an example of which type of study?

a)

Observational

b)

Experimental

c)

Cohort

d)

Case Control

e)

Clinical Trial

49.

The measure of association used in a case-control study is:

a)

Relative Risk

b)

Ecologic Correlation

c)

Odds Ratio

50.

Analytic epidemiology is a tool that epidemiologists use to do which of the following?

a)

Test the Hypotheses

b)

Assess whether an exposure is a possible cause of a disease, or outcome

c)

Test a potential association between exposures and outcome

d)

All of the above

51.

Interventions for reducing disability

a)

Secondary prevention

b)

Primary prevention

c)

Tertiary prevention

d)

Cheapest prevention

52.

A study in which children are randomly assigned to receive either a newly formulated vaccine or the currently available vaccine, and are followed to monitor for side effects and effectiveness of each vaccine, is an example of which type of study?

a)

Observational

b)

Cohort

c)

Clinical trial

d)

Case-control

53.

Which term refers to the ability of a measuring instrument to give consistent resuits on repeated trials?

a)

Sensitivity

b)

Reliability

c)

Validity

54.

Prevalence refers to:

a)

The number of existing cases of a disease or health condition, or deaths in a population at some designated time

b)

A summary rate based on the actual number of events in a population over a given time period

c)

The occurrence of new disease or mortality within a defined period of observation in a specific population

55.

Steps in practicing EBM, which ones are the first 3 things to do?

a)

Formulate clinical problems in answerable questions, search the best evidence and apply the evidence

b)

Formulate clinical problems in answerable questions, search the best evidence, critically appraise the evidence (VIA)

c)

Formulate clinical problems in answerable questions, critically appraise the evidence (VIA) and apply the evidence

d)

Formulate clinical problems in answerable questions, Search the best evidence, evaluate the evidence

56.

Association does not conflict with current knowledge of natural history and biology of disease

a)

Specificity

b)

Temporarily

c)

Strength of Association

d)

Dose Response

e)

Plausibility/Coherence

57.

Which of the following is not an advantage of a prospective cohort study?

a)

Precise measurement of exposure is possible

b)

Recall bias is minimized compared with a case-control study

c)

Many Disease outcomes can be studied simultaneously

d)

It usually costs less than a case-control study

e)

Incidence rates can be calculated

58.

Which of the following is NOT a common measure of association in epidemiologic studies?

a)

Odds ratio

b)

Hazard ratio

c)

Relative risk

d)

Mean difference

59.

The Causal Factor must precede the disease in time

a)

Temporarily

b)

Dose Response

c)

Strength of Association

d)

Specificity

e)

Plausibility

60.

This Design will have potential for recall bias:

a)

Cohort

b)

Cross Sectional

c)

Experimental

d)

Case Control

61.

Cross-Over is one of the methods for

a)

Case Series

b)

Clinical Trial

c)

Cohort

d)

Case Control

e)

Cross-sectional Study

62.

This classifies the occurrence of disease according to the variables of person, place, and time:

a)

Descriptive Epidemiology

b)

Environmental Epidemiology

c)

Analytic Epidemiology

63.

In one class there are 10 male and 20 female get dengue fever. What is the risk/proportion of male to get dengue fever?

a)

3/10

b)

1/2

c)

10/100

d)

1/3

e)

3/7

64.

Blinding is one of the process selection of subject for design study:

a)

Case Control

b)

Clinical Trial

c)

Cross-sectional Study

d)

Cohort

e)

Case Series

65.

In a cohort study of hormone replacement therapy and the risk of developing... atherosclerotic coronary artery disease, high economic status is associated with both use of hormone replacement therapy and the risk of developing coronary artery disease. This is the type of Error?

a)

Reverse Time Order

b)

Selection Bias

c)

Confounding

d)

Misclassification

66.

An advertisement in a medical journal stated that: "2,000 subjects with sore throats were treated with our new medicine. Within 4 days, 94% were asymptomatic." The advertisement claims that the medicine was effective. Based on the evidence given above, the claim:

a)

May be incorrect because no test of statistical significant was used.

b)

May be incorrect because no control or comparison group was involved

c)

Мay be incorrect because of failure to recognize a long-term cohort

67.

Identify people in whom a disease HAS ALREADY BEGUN but who have no Clinical signs and Symptoms of the Illness

a)

Tertiary prevention

b)

Primary prevention

c)

Secondary prevention

d)

Cheapest prevention

68.

In January, there were 50 cases of malaria diagnosed in District X, which has a population of 200,000. Of these, 30 were in males and 20 were in females. What is the ratio of male cases to female cases?

a)

50/200,000

b)

30/50

c)

30/20

d)

30/200,000

69.

The physical examination records ofthe entire incoming freshman class of 1935 at the University of Minnesota were examined in 1977 to see if their recorded height and weight at the time of admission to the university was related to the development of coronary heart disease by 1986. This is an example of:

a)

Case control study

b)

Retrospective cohort study

c)

Cross-sectional study

d)

Experimental study

e)

Concurrent/Prospective cohort study

70.

Selection bias cause by?

a)

The use of volunteers

b)

Paid participation

c)

Data from hospitals

d)

Using working populations

e)

All of the above

71.

How is Covid19 passed on?

a)

Through droplets that come from mouth and nose when confirm positive covid19 cough or breathe out

b)

In sexual fluids

c)

By drinking unclean water

72.

An investigator wants to know about the health effects of a particular exposure.... recruits a group of people who work in a location where the exposure is present, ana recruits a separate group of people who work in a location where the exposure is not present. The investigator follows both of the groups for several years to assess whether one group experiences more diagnosed health problems than the other group. What type of study design is this?

a)

Cross Sectional

b)

Cohort

c)

Case Control

d)

Experimental Study

73.

Which one is the best and cheapest but have best way for prevention of disease:

a)

Secondary prevention

b)

Tertiary prevention

c)

Primary prevention

74.

Which of the following terms refers to a study in which the units of analysis are populations or groups of people rather than individuals?

a)

Cohort Study

b)

Case-Control Study

c)

Eсologic Study

75.

Persons who have increasingly higher exposure levels have increasingly higher risk of disease

a)

Strength of Association

b)

Temporarily

c)

Plausibility/Coherence

d)

Dose Response

e)

Specificity

76.

Analytic epidemiology answers which questions about the occurrence of a health problem?

a)

Descriptive Epidemiology

b)

Why and how

c)

Place Person and Time

d)

Finding the clue

77.

The measure of association used in a cohort study is:

a)

Relative Risk

b)

Ecologic Correlation

c)

Odds Ratio

78.

_ results from differences between the study subjects in a sample and the popuratioT which they are selected to represent.

a)

Information bias

b)

Confounding

c)

Selection bias

d)

Interaction

79.

Loss to follow up is weakness of

a)

Case Control

b)

Cohort

c)

Cross Sectional

d)

Experimental

80.

Which of the following best describes the role of secondary prevention in

a)

Identifying and addressing the root causes of diseases

b)

Promoting healthy behaviors and lifestyles

c)

Preventing the spread of infectious diseases

d)

Early detection and treatment of diseases to prevent complications

81.

A study in which children are randomly assigned to receive either a newly formulated vaccine or the currently available vaccine, and are followed to monitor for side effects and effectiveness of each vaccine, is an example of which type of study?

a)

Case-control

b)

Clinical Trial/Experiment

c)

Observational

d)

Cohort

82.

An investigator seeks out cases of a particular disease that she wishes to study. She then recruits people who do not have this disease from the same population. For each study participant, she researches past exposures to compare the exposures of those who have the disease to the exposures of those who do not have the disease. What type of study design is this?

a)

Cross Sectional

b)

Cohort

c)

Experimental Study

d)

Case Control

83.

The relative risk is the incidence in the exposed divided by the incidence in the nonexposed.

a)

false

b)

true

84.

the black death was thought to be an epidemic of:

a)

bubonic plague

b)

cholera

c)

smallpox

85.

patient ask the doctor "how long do i have to live, doctor?" and the doctor replies, "six mponth to a year" the doctor are saying?

a)

diagnostic

b)

therapeutic

c)

etiologic

d)

prognostic

86.

Validity can be defined as:

a)

The degree to which an instrument measures what it is supposed to measure

b)

Concerned with measuring the frequency of new cases with reliability

c)

The degree to which results are consistent on a repeat measurement

d)

A measure of the degree or strength of association between two variables

87.

British investigators conducted a study to compare measles-mumps-rubella (MMR) vaccine history among 1,294 children with pervasive development disorder (e.g., autism and Asperger's syndrome) and 4,469 children without such disorders. (They found no association.) This is an example of which type(s) of study?

a)

Clinical trial

b)

Case Report

c)

Experimental

d)

Observational Study

88.

What effect (if any) would you expect if the interviewers were aware of the... of the study subjects?

a)

It could damage the validity of the results by introducing interviewer bias

b)

The results would likely not change

c)

It would benefit the validity of the results since the interviewers would understand more precisely how the exposure is related to the disease and collect better data for the cases

89.

What is the significance of a 95% confidence interval in epidemiology?

a)

It represents the probability that the study findings are correct

b)

It is used to calculate the p-value of a study

c)

It provides a range within which the true value is likely to fall with 95% confidence

d)

It indicates that the study has a 95% chance of being accurate

90.

The major purpose of random assignment in a clinical trial is to:

a)

Help ensure those study subjects are representative of the general population

b)

Facilitate double blinding (masking)

c)

Facilitate the measurement of outcome variable

d)

Reduce selection bias in the allocation of treatment

e)

Ensure that the study groups have comparable baseline characteristics

91.

A term that refers to any quantity that varies:

a)

Mode

b)

Variable

c)

Association

92.

Using the mask for healthy people, when they go out is:

a)

Secondary Prevention

b)

Tertiary Prevention

c)

Primary Prevention

93.

The Highest Risk for Covid transmission:

a)

Droplets

b)

Air-borne

c)

Skin contact

94.

What is Evidence based medicine?

a)

Integration of patient value, cost effectiveness analysis and published expert opinion

b)

Integration of cost effectiveness analysis, best research evidence and goop clinical expertise

c)

Integration of good clinical expertise, published trials and patient value

d)

Integration of best research evidence, good clinical expertise and patient value

e)

Integration of good clinical expertise, cost effectiveness value and research evidence

95.

What is the primary focus of secondary prevention in healthcare?

a)

To provide rehabilitation services

b)

To identify and treat diseases at an early stage

c)

To promote healthy lifestyle choices

d)

To prevent the onset of diseases

96.

a 12 month old girl coming to your clinic with pallor. his mother worry that she has thalassemia. from the history of feeding she is a very picky eater. she seldom eats red meat nor liver. you suspect anemia due to iron deficiency. the clinic only can perform complete blood count. which one of the following is the correct outcome for this situation

a)

to develop diagnosis of thallasemia

b)

to develop diagnosis of anemia

c)

to differentiate iron deficiency anemia from thallasemia

d)

to differentiate thallasemia from anemia

e)

to develop diagnosis of iron deficiency anemia

97.

the type of association in which an increase in the value of one variable is linked with a decrease in the value of another variable

a)

continuous

b)

negative

c)

positive

98.

in epidemiology, what is the bradford hill criteria used for?

a)

assessing the quality of research design in studies

b)

identifying cofounding variables in research

c)

determining causation between exposure and outcome

d)

evaluating the statistical significance of research findings

99.

The Primary Goal of Public health (primary prevention) is to:

a)

Protect the infected

b)

Protect the uninfected

100.

About 400 patients take a diagnostic test. There are:

180 True Positives

8 False Positives

190 True Negatives

22 False Negatives

What is the sensitivity and specificity of this test?

a)

Sensitivity: 95.96; Specificity: 89.11

b)

Sensitivity: 89.11; Specificity: 95.96

c)

Sensitivity: 95.74; Specificity: 89.62

d)

Sensitivity: 89.62; Specificity: 95.74