Worksheetsfinal
Total questions: 100
Worksheet time: 50mins
a cohort study differs from a case-control study in that:
subjects are enrolled or categorized on the basis of their exposure status in a cohort study but not in a case control study
cohort studies require many years to conduct, but case-control studies do not
cohort studies are conducted to investigate chronic diseases, case-control studies are used for infectious diseases
subjects are asked about their exposure status in a cohort study but not in a case-control study
what is 'selection bias' in epidemiological research?
bias that occurs due to confounding factors affecting research outcomes
bias that arises because the research is conducted by less-experienced researchers
bias that arises when the research sample does not represent the entire population
bias that occurs due to a cause-and-effect relationship between independent variables
in one class there are 10 male and 20 female get dengue fever. what is the ratio of female to get dengue fever?
3/7
2/3
1/2
2/10
2/1
which of the following is an example of a vector-borne disease
malaria
hiv/aids
influenza
diabetes
can you always tell if someone has covid-19
yes. you can tell just by where a person comes from, their race and ethnicity
yes-it will be obvious, a person with covid-19 coughs a lot
no-not everyone with covid-19 has symptoms
when the participants in behavioral studies change their behavior or performance in response to being observed
selection bias
hawthorne bias
confounding
_ is a non-causal association between an exposure and outcome due to the influence of a third variable
selection bias
interaction
information bias
confounding
which of the following are goals of vaccination?
prevent infection
prevent disease
prevent transmission
all of the above
john snow's investigation of cholera is considered a model for epidemiologic field investigation because it included a:
comparison of a health outcome among exposed and unexposed groups
using microscope to prove the vibrio cholera
the occurrence of new disease or mortality within a defined period of observation in a specific population is
incidence
prevalence
obtaining information about exposures that occurred in the future is considered
ecological fallacy
prospective approach
retrospective approach
in january, there were 50 cases of malaria diagnosed in district x, which has a population of 200,000. of these, 30 were in males and 20 were in females. what is the proportion if the cases were in females?
20/50
30/200,000
50/200,000
30/50
the implementation of health education programs is an example of:
tertiary prevention
secondary prevention
primary prevention
reducing the impact of disease/complication
primary prevention
tertiary prevention
secondary prevention
cheapest prevention
there may be a spurious association between diseases or between a characterized disease because of the different probabilities of admission to a hospital for those with the disease, without the disease and with the characteristic of interest
berksonian bias
measurement bias
information bias
Residence of three villages with three different types of water supply were asked to participate in a survey to identify cholera carriers. Because several cholera deaths had occurred recently, virtually everyone present at the time underwent examination. The proportion of residents in each village who were carriers was computed and compared. What is the proper classification for this study?
Nonconcurrent/Retrospective cohort study
Concurrent/Prospective cohort study
Cross-sectional study
Experimental study
Those who agree to be in a study may be in some way different from those who refuse to participate (......)
Chance
Confounding
Reverse Time Order
Bias
Causal
Tertiary prevention is intended to reduce the duration and severity of disease.
False
True
All of the following are important criteria when making causal inferences except
Strength of association
Consistency with existing knowledge
Predictive value
Consistency of association in several studies
Dose-response relationship
in a case-control study of the relationship between a cholesterol lowering drug and the risk of developing breast cancer, control subjects are sampled from participants in health screening fair. this is the type of error?
confounding
reverse time order
selection bias
misclassification
reliability can be defined as:
the degree to which results are consistent
ensuring that patients all take a test under the same conditions
the degree to which an instrument measures what it is supposed to measure
concerned with measuring the frequency of new cases with reliability
a measure of degree of strength of association between two variables
Mammography screening (screening for breast cancer) for women age more than 40 years old
Secure prevention
Primary prevention
Secondary prevention
Cheapest prevention
Tertiary prevention
What is the primary purpose of a randomized controlled trial (RCT) in epidemiology?
To determine the prevalence of a disease in a population
To study historical trends in disease incidence
To conduct interviews with cases and controls
To establish cause-and-effect relationships between exposures and outcomes
A large population is surveyed to determine the prevalence of this newly recognized disease by age, gender, and ethnicity
Descriptive Study
Case control
Experimental Study
Cohort
The Most Expensive of Prevention
Tertiary prevention
Primary prevention
Secondary prevention
Cheapest prevention
This stage of prevention is intended to reduce complications and disabilities.
primary prevention
secondary prevention
tertiary prevention
In a small pilot study, 12 women with endometrial cancer (cancer of the uterus.....) women with no apparent disease were contacted and asked whetherthey nau ever usen estrogen. Each woman with cancer was matched by age, race, weight, and parity to a woman without disease. What kind of study design is this?
Concurrent/Prospective cohort
Cross-sectional
Retrospective cohort t
Case-Control
Experimental
The proportion of people with the disease whose father has the disease is compared with control the corresponding proportion for people without the disease
Cross sectional
Experimental Study
Cohort
Case control
An association between two variables can be:
Only Positive
Only Negative
Either Positive or Negative
In 1796, Edward Jenner gave smallpox vaccine for kids to prevent the smallpox
Primary prevention
Cheapest prevention
Tertiary prevention
Secondary prevention
This criterion specifies that one must observe the cause before the effect:
Plausibility
Biological Gradient
Temporality
To assess the association between Kawasaki syndrome (KS) and carpet shampoо, investigators conducted a case-control study with 100 cases (children with KS) and 100 controls (children without KS). Among the children with KS, 50 had a history of recent exposure to carpet shampoo. Among the controls, the number with a recent history of exposure to carpet shampoo was 25. For this study, the odds ratio was:
3.0
0.3
1.1
2
The indicator for measures of the strength of an association.
Consistency of previous study
Relative Risk
Reliability
Dose Response
What is the primary goal of epidemiology?
To prevent and control diseases in populations
To promote healthy lifestyles
Which of the following is NOT an analytic study design?
Cohort
Experimental Study
Case Control
Descriptive study
Race and socioeconomic status are examples of:
Person Variables
Secular Trends
Clustering
Which of the following is NOT an advantage of a prospective cohort study?
Recall bias is minimized compared with a case-control study
Many disease outcomes can be studied simultaneously
Incidence rates can be calculated
Price measurement of exposure is possible
It is usually costs less than a case control study
What is the main goal of primary prevention?
To prevent diseases from occurring in the first place
To provide rehabilitation services
To identify and treat diseases early
To reduce the impact of an existing disease
An investigator assigns a specific exposure (a new formulation of a common medication) to some participants but assigns a different exposure (the original formulation of the medication) to others. During the study period, the investigator follows both groups to determine whether the new formulation works better and/or has fewer side effects. What type of study design is this?
Cross Sectional
Case Control
Cohort
Experimental Study
A Single Exposure should cause a single disease
Dose Response
Temporarily
Plausibility
Strength of Association
Specificity
Researchers investigated the relationship between the use of statins and p mortality by examining the records of patients who died from prostate cancer as well as records of matched controls. They report an odds ratio of 1.49 (95% confidence interval, 1.34-1.70 (P Value<0.0001). What can you conclude from these results?
Statins significantly lower the risk of death from prostate cancer
Statins have no effect on cancer mortality
Statins do not significantly lower the risk of death from prostate cancer
Statins do not significantly increase the risk of death from prostate cancer
Statins significantly increase the risk of death from prostate cancer
Race and socioeconomic status are examples of:
Person Variables
Clustering
Secular Trends
The relative risk and the odds ratio are important measures of the strength of an association
false
true
Aim of Descriptive Epidemiology:
Explain WHY the Risk Factors and Causal of Disease
Describe the Distribution of Disease based on Person Place and Time
Estimate/predict the Disease outcome
Give the recomendation how to control disease
A case-control study is characterized by al of the following except:
Definition of cases may be difficult
It is relatively inexpensive compared with most other epidemiologic study designs
Incidence rates may be computed directly
Patients with the disease (cases) are compared with persons without the disease (control)
Assessment of past exposure may be biased
Which of the following is an example of a type of descriptive epidemiologic study?
Case Reports
Case-Control Study
Cohort Study
Now, covid-19 has become:
Pandemic Disease
Epidemic Disease
Endemic Disease
A study in which children are randomly assigned to receive either a newly formulated vaccine or the currently available vaccine, and are followed to monitor for side effects and effectiveness of each vaccine, is an example of which type of study?
Observational
Experimental
Cohort
Case Control
Clinical Trial
The measure of association used in a case-control study is:
Relative Risk
Ecologic Correlation
Odds Ratio
Analytic epidemiology is a tool that epidemiologists use to do which of the following?
Test the Hypotheses
Assess whether an exposure is a possible cause of a disease, or outcome
Test a potential association between exposures and outcome
All of the above
Interventions for reducing disability
Secondary prevention
Primary prevention
Tertiary prevention
Cheapest prevention
A study in which children are randomly assigned to receive either a newly formulated vaccine or the currently available vaccine, and are followed to monitor for side effects and effectiveness of each vaccine, is an example of which type of study?
Observational
Cohort
Clinical trial
Case-control
Which term refers to the ability of a measuring instrument to give consistent resuits on repeated trials?
Sensitivity
Reliability
Validity
Prevalence refers to:
The number of existing cases of a disease or health condition, or deaths in a population at some designated time
A summary rate based on the actual number of events in a population over a given time period
The occurrence of new disease or mortality within a defined period of observation in a specific population
Steps in practicing EBM, which ones are the first 3 things to do?
Formulate clinical problems in answerable questions, search the best evidence and apply the evidence
Formulate clinical problems in answerable questions, search the best evidence, critically appraise the evidence (VIA)
Formulate clinical problems in answerable questions, critically appraise the evidence (VIA) and apply the evidence
Formulate clinical problems in answerable questions, Search the best evidence, evaluate the evidence
Association does not conflict with current knowledge of natural history and biology of disease
Specificity
Temporarily
Strength of Association
Dose Response
Plausibility/Coherence
Which of the following is not an advantage of a prospective cohort study?
Precise measurement of exposure is possible
Recall bias is minimized compared with a case-control study
Many Disease outcomes can be studied simultaneously
It usually costs less than a case-control study
Incidence rates can be calculated
Which of the following is NOT a common measure of association in epidemiologic studies?
Odds ratio
Hazard ratio
Relative risk
Mean difference
The Causal Factor must precede the disease in time
Temporarily
Dose Response
Strength of Association
Specificity
Plausibility
This Design will have potential for recall bias:
Cohort
Cross Sectional
Experimental
Case Control
Cross-Over is one of the methods for
Case Series
Clinical Trial
Cohort
Case Control
Cross-sectional Study
This classifies the occurrence of disease according to the variables of person, place, and time:
Descriptive Epidemiology
Environmental Epidemiology
Analytic Epidemiology
In one class there are 10 male and 20 female get dengue fever. What is the risk/proportion of male to get dengue fever?
3/10
1/2
10/100
1/3
3/7
Blinding is one of the process selection of subject for design study:
Case Control
Clinical Trial
Cross-sectional Study
Cohort
Case Series
In a cohort study of hormone replacement therapy and the risk of developing... atherosclerotic coronary artery disease, high economic status is associated with both use of hormone replacement therapy and the risk of developing coronary artery disease. This is the type of Error?
Reverse Time Order
Selection Bias
Confounding
Misclassification
An advertisement in a medical journal stated that: "2,000 subjects with sore throats were treated with our new medicine. Within 4 days, 94% were asymptomatic." The advertisement claims that the medicine was effective. Based on the evidence given above, the claim:
May be incorrect because no test of statistical significant was used.
May be incorrect because no control or comparison group was involved
Мay be incorrect because of failure to recognize a long-term cohort
Identify people in whom a disease HAS ALREADY BEGUN but who have no Clinical signs and Symptoms of the Illness
Tertiary prevention
Primary prevention
Secondary prevention
Cheapest prevention
In January, there were 50 cases of malaria diagnosed in District X, which has a population of 200,000. Of these, 30 were in males and 20 were in females. What is the ratio of male cases to female cases?
50/200,000
30/50
30/20
30/200,000
The physical examination records ofthe entire incoming freshman class of 1935 at the University of Minnesota were examined in 1977 to see if their recorded height and weight at the time of admission to the university was related to the development of coronary heart disease by 1986. This is an example of:
Case control study
Retrospective cohort study
Cross-sectional study
Experimental study
Concurrent/Prospective cohort study
Selection bias cause by?
The use of volunteers
Paid participation
Data from hospitals
Using working populations
All of the above
How is Covid19 passed on?
Through droplets that come from mouth and nose when confirm positive covid19 cough or breathe out
In sexual fluids
By drinking unclean water
An investigator wants to know about the health effects of a particular exposure.... recruits a group of people who work in a location where the exposure is present, ana recruits a separate group of people who work in a location where the exposure is not present. The investigator follows both of the groups for several years to assess whether one group experiences more diagnosed health problems than the other group. What type of study design is this?
Cross Sectional
Cohort
Case Control
Experimental Study
Which one is the best and cheapest but have best way for prevention of disease:
Secondary prevention
Tertiary prevention
Primary prevention
Which of the following terms refers to a study in which the units of analysis are populations or groups of people rather than individuals?
Cohort Study
Case-Control Study
Eсologic Study
Persons who have increasingly higher exposure levels have increasingly higher risk of disease
Strength of Association
Temporarily
Plausibility/Coherence
Dose Response
Specificity
Analytic epidemiology answers which questions about the occurrence of a health problem?
Descriptive Epidemiology
Why and how
Place Person and Time
Finding the clue
The measure of association used in a cohort study is:
Relative Risk
Ecologic Correlation
Odds Ratio
_ results from differences between the study subjects in a sample and the popuratioT which they are selected to represent.
Information bias
Confounding
Selection bias
Interaction
Loss to follow up is weakness of
Case Control
Cohort
Cross Sectional
Experimental
Which of the following best describes the role of secondary prevention in
Identifying and addressing the root causes of diseases
Promoting healthy behaviors and lifestyles
Preventing the spread of infectious diseases
Early detection and treatment of diseases to prevent complications
A study in which children are randomly assigned to receive either a newly formulated vaccine or the currently available vaccine, and are followed to monitor for side effects and effectiveness of each vaccine, is an example of which type of study?
Case-control
Clinical Trial/Experiment
Observational
Cohort
An investigator seeks out cases of a particular disease that she wishes to study. She then recruits people who do not have this disease from the same population. For each study participant, she researches past exposures to compare the exposures of those who have the disease to the exposures of those who do not have the disease. What type of study design is this?
Cross Sectional
Cohort
Experimental Study
Case Control
The relative risk is the incidence in the exposed divided by the incidence in the nonexposed.
false
true
the black death was thought to be an epidemic of:
bubonic plague
cholera
smallpox
patient ask the doctor "how long do i have to live, doctor?" and the doctor replies, "six mponth to a year" the doctor are saying?
diagnostic
therapeutic
etiologic
prognostic
Validity can be defined as:
The degree to which an instrument measures what it is supposed to measure
Concerned with measuring the frequency of new cases with reliability
The degree to which results are consistent on a repeat measurement
A measure of the degree or strength of association between two variables
British investigators conducted a study to compare measles-mumps-rubella (MMR) vaccine history among 1,294 children with pervasive development disorder (e.g., autism and Asperger's syndrome) and 4,469 children without such disorders. (They found no association.) This is an example of which type(s) of study?
Clinical trial
Case Report
Experimental
Observational Study
What effect (if any) would you expect if the interviewers were aware of the... of the study subjects?
It could damage the validity of the results by introducing interviewer bias
The results would likely not change
It would benefit the validity of the results since the interviewers would understand more precisely how the exposure is related to the disease and collect better data for the cases
What is the significance of a 95% confidence interval in epidemiology?
It represents the probability that the study findings are correct
It is used to calculate the p-value of a study
It provides a range within which the true value is likely to fall with 95% confidence
It indicates that the study has a 95% chance of being accurate
The major purpose of random assignment in a clinical trial is to:
Help ensure those study subjects are representative of the general population
Facilitate double blinding (masking)
Facilitate the measurement of outcome variable
Reduce selection bias in the allocation of treatment
Ensure that the study groups have comparable baseline characteristics
A term that refers to any quantity that varies:
Mode
Variable
Association
Using the mask for healthy people, when they go out is:
Secondary Prevention
Tertiary Prevention
Primary Prevention
The Highest Risk for Covid transmission:
Droplets
Air-borne
Skin contact
What is Evidence based medicine?
Integration of patient value, cost effectiveness analysis and published expert opinion
Integration of cost effectiveness analysis, best research evidence and goop clinical expertise
Integration of good clinical expertise, published trials and patient value
Integration of best research evidence, good clinical expertise and patient value
Integration of good clinical expertise, cost effectiveness value and research evidence
What is the primary focus of secondary prevention in healthcare?
To provide rehabilitation services
To identify and treat diseases at an early stage
To promote healthy lifestyle choices
To prevent the onset of diseases
a 12 month old girl coming to your clinic with pallor. his mother worry that she has thalassemia. from the history of feeding she is a very picky eater. she seldom eats red meat nor liver. you suspect anemia due to iron deficiency. the clinic only can perform complete blood count. which one of the following is the correct outcome for this situation
to develop diagnosis of thallasemia
to develop diagnosis of anemia
to differentiate iron deficiency anemia from thallasemia
to differentiate thallasemia from anemia
to develop diagnosis of iron deficiency anemia
the type of association in which an increase in the value of one variable is linked with a decrease in the value of another variable
continuous
negative
positive
in epidemiology, what is the bradford hill criteria used for?
assessing the quality of research design in studies
identifying cofounding variables in research
determining causation between exposure and outcome
evaluating the statistical significance of research findings
The Primary Goal of Public health (primary prevention) is to:
Protect the infected
Protect the uninfected
About 400 patients take a diagnostic test. There are:
180 True Positives
8 False Positives
190 True Negatives
22 False Negatives
What is the sensitivity and specificity of this test?
Sensitivity: 95.96; Specificity: 89.11
Sensitivity: 89.11; Specificity: 95.96
Sensitivity: 95.74; Specificity: 89.62
Sensitivity: 89.62; Specificity: 95.74
