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Cengage Chapter 3 - Sources and Bodily Effects of Drugs

Total questions: 97

Worksheet time: 49mins

Name
Class
Date
1.

What is it called when drug effects are limited to one area of the body?

a)

Drug effect

b)

Systemic effects

c)

Local effects

d)

Lethal dose

2.

Which of the following is the term for cellular changes?

a)

Drug action

b)

Drug effect

c)

Systemic effects

d)

Local effects

3.

Which of the following is the term for drugs being absorbed and distributed throughout the body?

a)

Drug action

b)

Drug effect

c)

Systemic effects

d)

Local effects

4.

Which of the following is the term for physiological changes caused by a drug?

a)

Drug action

b)

Drug effect

c)

Systemic effects

d)

Local effects

5.

What term refers to the amount that will produce harmful side effects or symptoms of poisoning?

a)

Toxic dose

b)

Loading dose

c)

Dependence

d)

Tolerance

6.

What is the amount of drug required to sustain the desired effect called?

a)

Lethal dose

b)

Maintenance dose

c)

Toxic dose

d)

Loading dose

7.

What is the amount of drug that causes death called?

a)

Lethal dose

b)

Maintenance dose

c)

Toxic dose

d)

Loading dose

8.

What is the term for an acquired need for a drug that may produce symptoms when the drug is discontinued?

a)

Systemic effects

b)

Local effects

c)

Dependence

d)

Tolerance

9.

Lethal dose is the amount of drug that causes death.

a)

Correct

b)

Maintenance dose

c)

Toxic dose

d)

Loading dose

10.

What is a decreased response to a drug called?

a)

Systemic effects

b)

Local effects

c)

Dependence

d)

Tolerance

11.

What is the movement from blood into tissues and fluids called?

a)

Excretion

b)

Metabolism

c)

Distribution

12.

What is the movement of a drug from the blood into tissues and fluids called?

a)

Excretion

b)

Metabolism

c)

Distribution

d)

Absorption

13.

What are the alterations the drug undergoes in the body called?

a)

Excretion

b)

Metabolism

c)

Distribution

d)

Absorption

14.

What is the movement of the drug into the bloodstream called?

a)

Excretion

b)

Metabolism

c)

Distribution

d)

Absorption

15.

What is the elimination of the drug from the body called?

a)

Excretion

b)

Metabolism

c)

Distribution

d)

Absorption

16.

What are the increased effects of a drug due to a build-up in the body called?

a)

Excretion

b)

Metabolism

c)

Distribution

d)

Cumulative effects

17.

What are inactive substances that resemble a medication, although no drug is present?

a)

Antagonism

b)

Potentiation

c)

Synergism

d)

Placebo

18.

What is the condition resulting from exposure to either a poison or a dangerous amount of a drug that is normally safe when given in a smaller amount called?

a)

Antagonism

b)

Potentiation

c)

Synergism

19.

Which of the following is the condition resulting from exposure to either a poison or a dangerous amount of a drug that is normally safe when given in a smaller amount?

a)

Antagonism

b)

Potentiation

c)

Synergism

d)

Toxicity

20.

What are the opposing actions of two drugs in which one decreases or cancels out the effect of the other called?

a)

Antagonism

b)

Potentiation

c)

Synergism

d)

Placebo

21.

What is the action of two drugs in which one prolongs or multiplies the effect of the other?

a)

Antagonism

b)

Potentiation

c)

Synergism

d)

Toxicity

22.

What is the action of two drugs working together in which one helps the other simultaneously for an effect that neither could produce alone called?

a)

Antagonism

b)

Potentiation

c)

Synergism

d)

Placebo

23.

What are the unique, unusual, and unexpected responses to a drug called?

a)

Paradoxical effect

b)

Anaphylactic reaction

c)

Hypersensitivity

d)

Idiosyncrasy

24.

What is the term for the unique, unusual, and unexpected responses to a drug?

a)

Paradoxical effect

b)

Anaphylactic reaction

c)

Hypersensitivity

d)

Idiosyncrasy

25.

What is the immune response to a drug called?

a)

Paradoxical effect

b)

Anaphylactic reaction

c)

Hypersensitivity

d)

Idiosyncrasy

26.

What are the effects from maternal drug administration that cause physical defects in a fetus called?

a)

Paradoxical effect

b)

Anaphylactic reaction

c)

Hypersensitivity

d)

Teratogenic effect

27.

What is the opposite effect from what was expected called?

a)

Paradoxical effect

b)

Anaphylactic reaction

c)

Hypersensitivity

d)

Idiosyncrasy

28.

Which of the following is the term for a severe, possibly fatal allergic response to a drug?

a)

Paradoxical effect

b)

Anaphylactic reaction

c)

Hypersensitivity

d)

Idiosyncrasy

29.

Drug studies have revealed an adverse risk to the fetus, and the benefit-to-risk ratio must be established before use during pregnancy. Which category is this drug in?

a)

Pregnancy Category A

b)

Pregnancy Category B

c)

Pregnancy Category C

d)

Pregnancy Category D

30.

Which of the following is the pregnancy category for drugs that have shown teratogenic effects, and the drug is contraindicated?

a)

Pregnancy Category A

b)

Pregnancy Category B

c)

Pregnancy Category C

d)

Pregnancy Category X

31.

Which of the following is the category for drugs that have shown teratogenic effects, and the drug is contraindicated?

a)

Pregnancy Category A

b)

Pregnancy Category B

c)

Pregnancy Category C

d)

Pregnancy Category X

32.

Which of the following is the category for drugs that have not yet been tested in pregnant women or animals?

a)

Pregnancy Category A

b)

Pregnancy Category B

c)

Pregnancy Category C

d)

Pregnancy Category D

33.

Which of the following is the category for drugs that are shown to be safe to the fetus?

a)

Pregnancy Category A

b)

Pregnancy Category B

c)

Pregnancy Category C

d)

Pregnancy Category D

34.

Which of the following is the category for drugs not studied on pregnant women, but animal studies have not shown fetal risk?

a)

Pregnancy Category A

b)

Pregnancy Category B

c)

Pregnancy Category C

d)

Pregnancy Category D

35.

Which of the following is the category for drugs not studied on pregnant women, but animal studies have not shown fetal risk?

a)

Pregnancy Category A

b)

Pregnancy Category B

c)

Pregnancy Category C

d)

Pregnancy Category D

36.

Which of the following is the term for an unintended effect or side effect causing a negative reaction?

a)

Prodrug

b)

Pharmacogenomics

c)

Chemoinformatics

d)

ADR (adverse drug reaction)

37.

What is the science that helps us know if a drug will be effective or possibly toxic based on genetics?

a)

Prodrug

b)

Pharmacogenomics

c)

Chemoinformatics

d)

ADR (adverse drug reaction)

38.

What is the term for using computers, statistics, and mathematics to analyze how drug molecules might work?

a)

Prodrug

b)

Pharmacogenomics

c)

Chemoinformatics

d)

ADR (adverse drug reaction)

39.

Which of the following is a drug that is not active until it has been metabolized?

a)

Prodrug

b)

Pharmacogenomics

c)

Chemoinformatics

d)

ADR (adverse drug reaction)

40.

What is a prodrug?

a)

A drug that is not active until it has been metabolized.

b)

Pharmacogenomics is the science that helps us know if a drug will be effective or possibly toxic based on genetics.

c)

Cheminformatics is the term for using computers, statistics, and mathematics to analyze how drug molecules might work.

d)

ADR stands for adverse drug reactions.

41.

What is the term related to the desired blood level to achieve desired effect without serious side effects?

a)

Prodrug

b)

Pharmacogenomics

c)

Cheminformatics

d)

Therapeutic range

42.

What is the most actively pursued source of new drugs?

a)

Plants

b)

Minerals

c)

Animal sources

d)

Synthetics

43.

What are the cellular changes a drug produces in the body called?

a)

Drug actions

b)

Drug effect

c)

Systemic effect

d)

Absorption

44.

What are the cellular changes produced by a drug related to?

a)

Drug actions

b)

Physiological change

c)

Systemic effect

d)

Absorption

45.

What are the physiological changes caused by drugs called?

a)

Drug effects

b)

Drug actions

c)

Systemic effect

d)

Absorption

46.

What is it called when medication reaches widespread areas of the body?

a)

Drug effect

b)

Drug action

c)

Systemic effect

d)

Local effect

47.

What is it called when the medication’s effect is limited to the area of the body where it is administered?

a)

Drug effect

b)

Drug action

c)

Systemic effect

d)

Local effect

48.

What is the term for the effect of a drug that is limited to one area of the body (typically topical medications)?

a)

Systemic effect

b)

Local effect

49.

What is the term for the initial high dose used to quickly elevate the level of the drug in the blood?

a)

Maximum dose

b)

Loading dose

c)

Therapeutic dose

d)

Lethal dose

50.

Which of these is used for keeping the blood level of the drug at a steady state in order to maintain the desired effect?

a)

Minimum dose

b)

Maintenance dose

c)

Therapeutic dose

d)

Maximum dose

51.

Which of these is used for keeping the blood level of the drug at a steady state in order to maintain the desired effect?

a)

Minimum dose

b)

Maintenance dose

c)

Therapeutic dose

d)

Maximum dose

52.

What is the amount of a drug that will produce harmful side effects or symptoms of poisoning called?

a)

Maximum dose

b)

Toxic dose

c)

Lethal dose

d)

Loading dose

53.

What is a dose that causes death called?

a)

Maximum dose

b)

Toxic dose

c)

Lethal dose

d)

Loading dose

54.

Where does absorption of a drug occur?

a)

Mucosa of the stomach, mouth, and small intestine

b)

Circulatory system

c)

Liver

d)

Kidneys, sweat glands, lungs, and intestines

55.

Where does absorption of a drug occur?

a)

Mucosa of the stomach, mouth, and small intestine

b)

Circulatory system

c)

Liver

d)

Kidneys, sweat glands, lungs, and intestines

56.

A lethal dose causes death.

a)

True

b)

False

57.

Where does distribution of a drug occur?

a)

Mucosa of the stomach, mouth, and small intestine

b)

Circulatory system

c)

Liver

d)

Kidneys, sweat glands, lungs, and intestines

58.

Where does metabolism of a drug occur?

a)

Mucosa of the stomach, mouth, and small intestine

b)

Circulatory system

c)

Liver

d)

Kidneys, sweat glands, lungs, and intestines

59.

What is the affinity or attraction of a drug to a specific organ or cell called?

a)

Selective distribution

b)

Toxicity

c)

Placebo

d)

Synergism

60.

Which of the following is a condition that may slow metabolism of a drug?

a)

Full or empty stomach

b)

Poor circulation

c)

Liver damage

d)

Renal (kidney) damage

61.

Which of the following is a condition that may slow excretion of a drug?

a)

Full or empty stomach

b)

Poor circulation

c)

Liver damage

d)

Renal (kidney) damage

62.

Which of the following is a condition that alters absorption of a drug?

a)

Full or empty stomach

b)

Poor circulation

c)

Liver damage

d)

Renal (kidney) damage

63.

Which of the following is a condition that may slow distribution of a drug?

a)

Full or empty stomach

b)

Poor circulation

c)

Liver damage

d)

Renal (kidney) damage

64.

Where does metabolism of a drug occur?

a)

Mucosa of the stomach, mouth, and small intestine

b)

Circulatory system

c)

Liver

d)

Kidneys, sweat glands, lungs, and intestines

65.

Where does excretion of a drug occur?

a)

Mucosa of the stomach, mouth, and small intestine

b)

Circulatory system

c)

Liver

d)

Kidneys, sweat glands, lungs, and intestines

66.

Which of the following can affect the speed and efficiency of drug processing in the body?

a)

Age, weight, sex, and psychological state

b)

Hair and eye color

c)

Education

d)

Hair color

67.

Which of the following is the fastest route of drug administration?

a)

Vaginal suppository

b)

Intravenous

c)

By mouth (PO)

d)

Rectal suppository

68.

What is an inactive substance that resembles a medication called?

a)

Selective distribution

b)

Toxicity

c)

Placebo

d)

Synergism

69.

What variables affect the speed and efficiency of drugs being processed by the body?

a)

Age, weight, sex, and psychological state

b)

Age, weight, and hair and eye color

c)

Weight, sex, and education

d)

Psychological state, sex, and hair color

70.

What is the opposing action of two drugs where one cancels out the other?

a)

Synergism

b)

Potentiation

c)

Potentiation

d)

Antagonism

71.

What is the condition that results from exposure to either a poison or a dangerous amount of a drug that is normally safe when given in a smaller amount called?

a)

Selective distribution

b)

Toxicity

c)

Placebo

d)

Synergism

72.

What is the action of two drugs working together in which one helps the other produce an effect that neither could produce alone?

a)

Selective distribution

b)

Toxicity

c)

Placebo

d)

Synergism

73.

What is the opposing action of two drugs in which one decreases or cancels out the effect of the other called?

a)

Placebo

b)

Synergism

c)

Potentiation

d)

Antagonism

74.

What is an undesired effect from maternal drug administration that causes the development of physical defects in a fetus called?

a)

Teratogenic effect

b)

Tolerance

c)

Hypersensitivity

d)

Anaphylactic reaction

75.

What is a unique, unusual response to a drug in a given patient called?

a)

Tolerance

b)

Idiosyncrasy

c)

Dependence

d)

Paradoxical

76.

What is a decreased response to a drug that develops after repeated doses are given called?

a)

Tolerance

b)

Dependence

c)

Anaphylactic reaction

d)

Hypersensitivity

77.

What is an acquired need for a drug that may produce psychological and/or physical symptoms of withdrawal when the drug is discontinued called?

a)

Tolerance

b)

Idiosyncrasy

c)

Dependence

d)

Paradoxical

78.

What is an immune response to a drug that may be of varying degrees called?

a)

Tolerance

b)

Dependence

c)

Anaphylactic reaction

d)

Hypersensitivity

79.

What is a severe, possibly fatal allergic response called?

a)

Tolerance

b)

Dependence

c)

Anaphylactic reaction

d)

Hypersensitivity

80.

What is an example of the use of recombinant DNA technology?

a)

Penicillin production

b)

Aspirin synthesis

c)

Morphine extraction

d)

Hepatitis B vaccine, insulin, and human growth hormone

81.

What is it called when a scientist inserts normal genes into a human chromosome?

a)

DNA therapy

b)

Gene therapy

c)

Chemoinformatics

d)

Chemical engineering

82.

What does genetic engineering do?

a)

Produces a perfect member of a species

b)

Alters genes in a lab setting

c)

Predicts a disease through evaluation of chromosomes

d)

Fixes the human genome

83.

What is recombinant DNA technology used to produce?

a)

Hepatitis B vaccine

b)

Insulin

c)

Human growth hormone

d)

All of the above

84.

What does the term chemoinformatics mean?

a)

Using the chemical name and mathematics to identify drugs and which patients will respond to them

b)

Using chemistry and statistics to define a particular substance

c)

Applying computer technology, statistics, and mathematics to study the structure, properties, and activities of molecules

d)

Combining chemistry and nursing informatics

85.

Which of the following is a sign of an anaphylactic reaction?

a)

Swelling of the lips and tongue

b)

Abdominal cramping

c)

Nausea and vomiting

d)

Headache

86.

Which of the following is/are signs of hypersensitivity?

a)

Rash and urticaria

b)

Nausea, vomiting, and diarrhea

c)

Headache

d)

Ringing in the ears

87.

Your cousin is started on medication after being diagnosed with epilepsy. Because they experience seizures quite often, they start with a very large dose of the anticonvulsant to elevate the levels of the drug in their blood as quickly as possible. What is this initial large dose called?

a)

Loading dose

b)

Shock dose

c)

Therapeutic dose

d)

Overdose

88.

Why are persons with liver failure particularly prone to experiencing the toxic effects of medications?

a)

They distribute the medication differently.

b)

They have increased renal excretion of drugs.

c)

They have enhanced drug absorption in the intestines.

d)

They have a stronger immune response to medications.

89.

You are reading about the treatment of cardiovascular disease and learn that some medications are more effective in African American patients than persons of other races. What is the study of why medications vary in effectiveness among groups known as?

a)

Cultural genetics

b)

Genetic therapy

c)

Behavioral genetics

d)

Pharmacogenomics

90.

Your friend is given an antianxiety medication before a medical procedure. Rather than relaxing, however, your friend becomes agitated and starts shouting at people. This type of reaction is known as:

a)

Paradoxical reaction

b)

Allergic reaction

c)

Withdrawal reaction

d)

Toxic reaction

91.

Why are patients with liver failure at risk when taking medication?

a)

The liver’s main role is distribution.

b)

They are unable to properly metabolize the medication.

c)

They absorb the medication too rapidly.

d)

They do not excrete the medication efficiently.

92.

Zach normally takes an antianxiety medication and, after he has his wisdom teeth pulled, takes a narcotic pain medication as well. He suddenly finds himself very drowsy and disoriented. What is this an example of?

a)

Anaphylaxis

b)

Tolerance

c)

Additive effect

d)

Antagonism

93.

Which of the following is the opposite of what was expected to occur?

a)

Reversal

b)

Anaphylactic reaction

c)

Antagonistic reaction

d)

Paradoxical reaction

94.

A patient is complaining that the new drug they started is not working at all. The patient also mentions that “they told me it was a useless drug when they gave me the prescription in the office.” What effect could describe the patient’s response to the drug?

a)

Perception effect

b)

Placebo effect

c)

Synergistic effect

d)

Paradoxical reaction

95.

Ozzie's doctor tells him not to take his tetracycline with dairy products because the calcium in the dairy products will form an insoluble complex with the tetracycline. What is this process called?

a)

Chelation

b)

Oxidation

c)

Adsorption

d)

Excretion

96.

Will visits the emergency department because of a badly broken leg. He is given a narcotic pain killer, but quickly becomes extremely dizzy and disoriented, and then vomits. Will is then given another medication, naloxone, and soon begins to feel better. Which of these refers to the effect of naloxone on the narcotic pain killer?

a)

Agonism

b)

Antagonism

c)

Potentiation

d)

Tolerance

97.

Where are drugs with an alkaline pH best absorbed?

a)

Small intestine

b)

Stomach

c)

Mouth

d)

Large intestine