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WorksheetsCengage Chapter 3 - Sources and Bodily Effects of Drugs
Total questions: 97
Worksheet time: 49mins
What is it called when drug effects are limited to one area of the body?
Drug effect
Systemic effects
Local effects
Lethal dose
Which of the following is the term for cellular changes?
Drug action
Drug effect
Systemic effects
Local effects
Which of the following is the term for drugs being absorbed and distributed throughout the body?
Drug action
Drug effect
Systemic effects
Local effects
Which of the following is the term for physiological changes caused by a drug?
Drug action
Drug effect
Systemic effects
Local effects
What term refers to the amount that will produce harmful side effects or symptoms of poisoning?
Toxic dose
Loading dose
Dependence
Tolerance
What is the amount of drug required to sustain the desired effect called?
Lethal dose
Maintenance dose
Toxic dose
Loading dose
What is the amount of drug that causes death called?
Lethal dose
Maintenance dose
Toxic dose
Loading dose
What is the term for an acquired need for a drug that may produce symptoms when the drug is discontinued?
Systemic effects
Local effects
Dependence
Tolerance
Lethal dose is the amount of drug that causes death.
Correct
Maintenance dose
Toxic dose
Loading dose
What is a decreased response to a drug called?
Systemic effects
Local effects
Dependence
Tolerance
What is the movement from blood into tissues and fluids called?
Excretion
Metabolism
Distribution
What is the movement of a drug from the blood into tissues and fluids called?
Excretion
Metabolism
Distribution
Absorption
What are the alterations the drug undergoes in the body called?
Excretion
Metabolism
Distribution
Absorption
What is the movement of the drug into the bloodstream called?
Excretion
Metabolism
Distribution
Absorption
What is the elimination of the drug from the body called?
Excretion
Metabolism
Distribution
Absorption
What are the increased effects of a drug due to a build-up in the body called?
Excretion
Metabolism
Distribution
Cumulative effects
What are inactive substances that resemble a medication, although no drug is present?
Antagonism
Potentiation
Synergism
Placebo
What is the condition resulting from exposure to either a poison or a dangerous amount of a drug that is normally safe when given in a smaller amount called?
Antagonism
Potentiation
Synergism
Which of the following is the condition resulting from exposure to either a poison or a dangerous amount of a drug that is normally safe when given in a smaller amount?
Antagonism
Potentiation
Synergism
Toxicity
What are the opposing actions of two drugs in which one decreases or cancels out the effect of the other called?
Antagonism
Potentiation
Synergism
Placebo
What is the action of two drugs in which one prolongs or multiplies the effect of the other?
Antagonism
Potentiation
Synergism
Toxicity
What is the action of two drugs working together in which one helps the other simultaneously for an effect that neither could produce alone called?
Antagonism
Potentiation
Synergism
Placebo
What are the unique, unusual, and unexpected responses to a drug called?
Paradoxical effect
Anaphylactic reaction
Hypersensitivity
Idiosyncrasy
What is the term for the unique, unusual, and unexpected responses to a drug?
Paradoxical effect
Anaphylactic reaction
Hypersensitivity
Idiosyncrasy
What is the immune response to a drug called?
Paradoxical effect
Anaphylactic reaction
Hypersensitivity
Idiosyncrasy
What are the effects from maternal drug administration that cause physical defects in a fetus called?
Paradoxical effect
Anaphylactic reaction
Hypersensitivity
Teratogenic effect
What is the opposite effect from what was expected called?
Paradoxical effect
Anaphylactic reaction
Hypersensitivity
Idiosyncrasy
Which of the following is the term for a severe, possibly fatal allergic response to a drug?
Paradoxical effect
Anaphylactic reaction
Hypersensitivity
Idiosyncrasy
Drug studies have revealed an adverse risk to the fetus, and the benefit-to-risk ratio must be established before use during pregnancy. Which category is this drug in?
Pregnancy Category A
Pregnancy Category B
Pregnancy Category C
Pregnancy Category D
Which of the following is the pregnancy category for drugs that have shown teratogenic effects, and the drug is contraindicated?
Pregnancy Category A
Pregnancy Category B
Pregnancy Category C
Pregnancy Category X
Which of the following is the category for drugs that have shown teratogenic effects, and the drug is contraindicated?
Pregnancy Category A
Pregnancy Category B
Pregnancy Category C
Pregnancy Category X
Which of the following is the category for drugs that have not yet been tested in pregnant women or animals?
Pregnancy Category A
Pregnancy Category B
Pregnancy Category C
Pregnancy Category D
Which of the following is the category for drugs that are shown to be safe to the fetus?
Pregnancy Category A
Pregnancy Category B
Pregnancy Category C
Pregnancy Category D
Which of the following is the category for drugs not studied on pregnant women, but animal studies have not shown fetal risk?
Pregnancy Category A
Pregnancy Category B
Pregnancy Category C
Pregnancy Category D
Which of the following is the category for drugs not studied on pregnant women, but animal studies have not shown fetal risk?
Pregnancy Category A
Pregnancy Category B
Pregnancy Category C
Pregnancy Category D
Which of the following is the term for an unintended effect or side effect causing a negative reaction?
Prodrug
Pharmacogenomics
Chemoinformatics
ADR (adverse drug reaction)
What is the science that helps us know if a drug will be effective or possibly toxic based on genetics?
Prodrug
Pharmacogenomics
Chemoinformatics
ADR (adverse drug reaction)
What is the term for using computers, statistics, and mathematics to analyze how drug molecules might work?
Prodrug
Pharmacogenomics
Chemoinformatics
ADR (adverse drug reaction)
Which of the following is a drug that is not active until it has been metabolized?
Prodrug
Pharmacogenomics
Chemoinformatics
ADR (adverse drug reaction)
What is a prodrug?
A drug that is not active until it has been metabolized.
Pharmacogenomics is the science that helps us know if a drug will be effective or possibly toxic based on genetics.
Cheminformatics is the term for using computers, statistics, and mathematics to analyze how drug molecules might work.
ADR stands for adverse drug reactions.
What is the term related to the desired blood level to achieve desired effect without serious side effects?
Prodrug
Pharmacogenomics
Cheminformatics
Therapeutic range
What is the most actively pursued source of new drugs?
Plants
Minerals
Animal sources
Synthetics
What are the cellular changes a drug produces in the body called?
Drug actions
Drug effect
Systemic effect
Absorption
What are the cellular changes produced by a drug related to?
Drug actions
Physiological change
Systemic effect
Absorption
What are the physiological changes caused by drugs called?
Drug effects
Drug actions
Systemic effect
Absorption
What is it called when medication reaches widespread areas of the body?
Drug effect
Drug action
Systemic effect
Local effect
What is it called when the medication’s effect is limited to the area of the body where it is administered?
Drug effect
Drug action
Systemic effect
Local effect
What is the term for the effect of a drug that is limited to one area of the body (typically topical medications)?
Systemic effect
Local effect
What is the term for the initial high dose used to quickly elevate the level of the drug in the blood?
Maximum dose
Loading dose
Therapeutic dose
Lethal dose
Which of these is used for keeping the blood level of the drug at a steady state in order to maintain the desired effect?
Minimum dose
Maintenance dose
Therapeutic dose
Maximum dose
Which of these is used for keeping the blood level of the drug at a steady state in order to maintain the desired effect?
Minimum dose
Maintenance dose
Therapeutic dose
Maximum dose
What is the amount of a drug that will produce harmful side effects or symptoms of poisoning called?
Maximum dose
Toxic dose
Lethal dose
Loading dose
What is a dose that causes death called?
Maximum dose
Toxic dose
Lethal dose
Loading dose
Where does absorption of a drug occur?
Mucosa of the stomach, mouth, and small intestine
Circulatory system
Liver
Kidneys, sweat glands, lungs, and intestines
Where does absorption of a drug occur?
Mucosa of the stomach, mouth, and small intestine
Circulatory system
Liver
Kidneys, sweat glands, lungs, and intestines
A lethal dose causes death.
True
False
Where does distribution of a drug occur?
Mucosa of the stomach, mouth, and small intestine
Circulatory system
Liver
Kidneys, sweat glands, lungs, and intestines
Where does metabolism of a drug occur?
Mucosa of the stomach, mouth, and small intestine
Circulatory system
Liver
Kidneys, sweat glands, lungs, and intestines
What is the affinity or attraction of a drug to a specific organ or cell called?
Selective distribution
Toxicity
Placebo
Synergism
Which of the following is a condition that may slow metabolism of a drug?
Full or empty stomach
Poor circulation
Liver damage
Renal (kidney) damage
Which of the following is a condition that may slow excretion of a drug?
Full or empty stomach
Poor circulation
Liver damage
Renal (kidney) damage
Which of the following is a condition that alters absorption of a drug?
Full or empty stomach
Poor circulation
Liver damage
Renal (kidney) damage
Which of the following is a condition that may slow distribution of a drug?
Full or empty stomach
Poor circulation
Liver damage
Renal (kidney) damage
Where does metabolism of a drug occur?
Mucosa of the stomach, mouth, and small intestine
Circulatory system
Liver
Kidneys, sweat glands, lungs, and intestines
Where does excretion of a drug occur?
Mucosa of the stomach, mouth, and small intestine
Circulatory system
Liver
Kidneys, sweat glands, lungs, and intestines
Which of the following can affect the speed and efficiency of drug processing in the body?
Age, weight, sex, and psychological state
Hair and eye color
Education
Hair color
Which of the following is the fastest route of drug administration?
Vaginal suppository
Intravenous
By mouth (PO)
Rectal suppository
What is an inactive substance that resembles a medication called?
Selective distribution
Toxicity
Placebo
Synergism
What variables affect the speed and efficiency of drugs being processed by the body?
Age, weight, sex, and psychological state
Age, weight, and hair and eye color
Weight, sex, and education
Psychological state, sex, and hair color
What is the opposing action of two drugs where one cancels out the other?
Synergism
Potentiation
Potentiation
Antagonism
What is the condition that results from exposure to either a poison or a dangerous amount of a drug that is normally safe when given in a smaller amount called?
Selective distribution
Toxicity
Placebo
Synergism
What is the action of two drugs working together in which one helps the other produce an effect that neither could produce alone?
Selective distribution
Toxicity
Placebo
Synergism
What is the opposing action of two drugs in which one decreases or cancels out the effect of the other called?
Placebo
Synergism
Potentiation
Antagonism
What is an undesired effect from maternal drug administration that causes the development of physical defects in a fetus called?
Teratogenic effect
Tolerance
Hypersensitivity
Anaphylactic reaction
What is a unique, unusual response to a drug in a given patient called?
Tolerance
Idiosyncrasy
Dependence
Paradoxical
What is a decreased response to a drug that develops after repeated doses are given called?
Tolerance
Dependence
Anaphylactic reaction
Hypersensitivity
What is an acquired need for a drug that may produce psychological and/or physical symptoms of withdrawal when the drug is discontinued called?
Tolerance
Idiosyncrasy
Dependence
Paradoxical
What is an immune response to a drug that may be of varying degrees called?
Tolerance
Dependence
Anaphylactic reaction
Hypersensitivity
What is a severe, possibly fatal allergic response called?
Tolerance
Dependence
Anaphylactic reaction
Hypersensitivity
What is an example of the use of recombinant DNA technology?
Penicillin production
Aspirin synthesis
Morphine extraction
Hepatitis B vaccine, insulin, and human growth hormone
What is it called when a scientist inserts normal genes into a human chromosome?
DNA therapy
Gene therapy
Chemoinformatics
Chemical engineering
What does genetic engineering do?
Produces a perfect member of a species
Alters genes in a lab setting
Predicts a disease through evaluation of chromosomes
Fixes the human genome
What is recombinant DNA technology used to produce?
Hepatitis B vaccine
Insulin
Human growth hormone
All of the above
What does the term chemoinformatics mean?
Using the chemical name and mathematics to identify drugs and which patients will respond to them
Using chemistry and statistics to define a particular substance
Applying computer technology, statistics, and mathematics to study the structure, properties, and activities of molecules
Combining chemistry and nursing informatics
Which of the following is a sign of an anaphylactic reaction?
Swelling of the lips and tongue
Abdominal cramping
Nausea and vomiting
Headache
Which of the following is/are signs of hypersensitivity?
Rash and urticaria
Nausea, vomiting, and diarrhea
Headache
Ringing in the ears
Your cousin is started on medication after being diagnosed with epilepsy. Because they experience seizures quite often, they start with a very large dose of the anticonvulsant to elevate the levels of the drug in their blood as quickly as possible. What is this initial large dose called?
Loading dose
Shock dose
Therapeutic dose
Overdose
Why are persons with liver failure particularly prone to experiencing the toxic effects of medications?
They distribute the medication differently.
They have increased renal excretion of drugs.
They have enhanced drug absorption in the intestines.
They have a stronger immune response to medications.
You are reading about the treatment of cardiovascular disease and learn that some medications are more effective in African American patients than persons of other races. What is the study of why medications vary in effectiveness among groups known as?
Cultural genetics
Genetic therapy
Behavioral genetics
Pharmacogenomics
Your friend is given an antianxiety medication before a medical procedure. Rather than relaxing, however, your friend becomes agitated and starts shouting at people. This type of reaction is known as:
Paradoxical reaction
Allergic reaction
Withdrawal reaction
Toxic reaction
Why are patients with liver failure at risk when taking medication?
The liver’s main role is distribution.
They are unable to properly metabolize the medication.
They absorb the medication too rapidly.
They do not excrete the medication efficiently.
Zach normally takes an antianxiety medication and, after he has his wisdom teeth pulled, takes a narcotic pain medication as well. He suddenly finds himself very drowsy and disoriented. What is this an example of?
Anaphylaxis
Tolerance
Additive effect
Antagonism
Which of the following is the opposite of what was expected to occur?
Reversal
Anaphylactic reaction
Antagonistic reaction
Paradoxical reaction
A patient is complaining that the new drug they started is not working at all. The patient also mentions that “they told me it was a useless drug when they gave me the prescription in the office.” What effect could describe the patient’s response to the drug?
Perception effect
Placebo effect
Synergistic effect
Paradoxical reaction
Ozzie's doctor tells him not to take his tetracycline with dairy products because the calcium in the dairy products will form an insoluble complex with the tetracycline. What is this process called?
Chelation
Oxidation
Adsorption
Excretion
Will visits the emergency department because of a badly broken leg. He is given a narcotic pain killer, but quickly becomes extremely dizzy and disoriented, and then vomits. Will is then given another medication, naloxone, and soon begins to feel better. Which of these refers to the effect of naloxone on the narcotic pain killer?
Agonism
Antagonism
Potentiation
Tolerance
Where are drugs with an alkaline pH best absorbed?
Small intestine
Stomach
Mouth
Large intestine
