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WorksheetsBody Water and Fluid Types
Total questions: 88
Worksheet time: 50mins
What is intravascular fluid?
What is interstitial fluid?
Total Body Water (TBW) in the average human is around ____ liters
34L
42L
50L
15L
TBW is roughly __% of total body weight
60%
70%
50%
40%
Mechanisms responsible for water loss
Excretion
Injury or trauma
Evaporation
Insensible fluid loss
Simple diffusion and facilitated diffusion require energy
True
False
NA+, K+ ATPase are considered active transporters and require energy
True
False
H20 flows across membranes ______ through ______
passively; osmosis
Pathway of the kidneys
Glomerulus > Proximal convoluted tubule > Loop of Henle > Distal Convoluted tubule > collecting ducts
Proximal convoluted tubule > Glomerulus > Loop of Henle > Distal Convoluted tubule > collecting ducts
Proximal convoluted tubule > Loop of Henle > > Distal Convoluted tubule > collecting ducts
The nephron can regenerate when damaged
True
False
We excrete roughly _-_ L per day
1-2
3-4
1-3
2-5
Reabsorption of water and solutes occurs throughout the nephron, whereas the reabsorption of most medications are found in
Movement of water and solutes from blood into urine is always a _____ ______ process
Active transport
Passive transport
Creatinine, H+, NH4+ and some drugs are secreted by the
distal convoluted tubule
proximal convoluted tubule
Loop of Henle reabsorbs only _____ in the descending limb
Water
Na+
Creatinine
Calcium
Which is reabsorbed in the ascending limb of the loop of Henle
Potassium and Calcium
Phosphorus
Sodium and Chloride
Water
Creatinine
Which is reabsorbed in the Distal convoluted tubule and Collecting duct
Sodium and Chloride
Phosphorus and Calcium
H+
Water
Loop diuretics target what within the kidney
Loop of Henle
DCT
PCT
Collecting ducts
Thiazide diuretics targets what part of the kidney
Loop of Henle
DCT
PCT
Collecting duct
Aldosterone antagonists target what part of the kidney
Loop of Henle
DCT
PCT
Collecting duct
Sodium, Potassium, Chloride, Bicarb, BUN, SCr and Glucose form what lab?
Basic Metabolic Panel (BMP)
Chem7
Calcium, Albumin, Total proteins, Bilirubin, Alkaline phos. trans. and amino is part of what labs?
Comprehensive Metabolic Panel (CMP) Chem14
Small molecules in water; distribute into tissues
Colloids
Crystalloids
Crystalloids consist of
Dextrose
Sodium chloride
Lactated ringers
Proteins
Big molecules in water
Colloids
Crystalloids
Colloids consist of
Proteins (albumin)
Polysaccharides
Dextrose
Sodium Chloride
Hypotonic saline requirements fall under what %
0.45%
0.7%
0.35%
0.8%
Isotonic saline requirements fall under what %
0.9%
0.6%
0.45%
0.35%
Hypertonic saline requirements fall under what %
3%
0.45%
5%
0.35%
Edema test indicates what severity at 2mm indention
Mild
Moderate
Severe
No edema
Edema test indicates what severity at 4mm indention
Mild
Moderate
Severe
Mod-Severe
Edema test indicates what severity at 6mm indention
Mod-severe
Moderate
Mild
No edema
Edema test indicates what severity at 8mm indention
Severe
Mod-severe
Moderate
Mild
Sodium (Na+) Indications
Extracellular
Most abundent
Least abundant
Hold water in cells
Sodium (Na+) S/S
Hyper/hyponatremia
Muscle cramps
Headaches and seizures
N/V and agitation
Classification of hyponatremia
Isotonic indicates
Normal osmolality
High osmolality
Low osmolality
Classification of hyponatremia
Hypotonic indicates
High osmolality
Low osmolality
Normal osmolality
Classification of hyponatremia
Hypertonic indicates
High osmolality
Low osmolality
Normal osmolality
Hyponatremia + Hypotonic
Fluctuating Na+
Increased TBW
Euvolemic
Hypervolemic
Hypovolemic
Hyponatremia + Hypotonic + Euvolemic
Risks
SIADH
Psychogenic
Polydipsia
Cirrhosis
Hyponatremia + Hypotonic
Increased Na+ concentration
Higher concentration of TBW than Na+
Euvolemic
Hypervolemic
Hypovolemic
Hyponatremia + Hypotonic + Hypervolemic
Risks
Heart failure
SIADH
Cirrhosis
Renal loss
Hyponatremia + Hypotonic
Major decrease in Na+
Decrease in TBW
Hypovolemic
Hypervolemic
Euvolemic
Hyponatremia + Hypotonic + Hypovolemic
risks
Renal loss
Cirrhosis
Heart failure
SIADH
Hyponatremia + Hypertonic
Hyperglycemia
Heart failure
Cirrhosis
Renal loss
Hyponatremia + Isotonic
Hyperproteinemia
HLD
Hyperglycemia
SIADH
Hypernatremia
Decrease TBW
Decrease Na+
Hypovolemic
Hypervolemic
Euvolemic
Hypernatremia + Hypovolemic
Causes
Severe diarrhea
Sweating
Hyperaldosteronism
Hypernatremia
Fluctuation of Na+
Decrease in TBW
Hypovolemic
Hypervolemic
Euvolemic
Hypernatremia + Euvolemic
Causes
Severe diarrhea
Sweating
Hyperaldosteronism
Increased insensible water loss
Hypernatremia
Increase TBW
Increase Na+
Hypovolemic
Hypervolemic
Euvolemic
Hypernatremia + Hypervolemic
causes
Severe diarrhea
Sweating
Increased administration of Na+
Hyperaldosteronism
Hypernatremia is always hypertonic
True
False
Potassium is the primary cation in the ________ space
Extracellular
Intracellular
Na+ - K+ - ATPase pump is key in regulating K+ balance
It transports ___ out of the cell and ___ into the cell
3:2 ratio
Na+ ; K+
K+ ; Na+
Na+ ; Na+
K+ ; K+
_______ is a cofactor in ATPase pump
Magnesium
Potassium
Phosphorus
Calcium
__________ rely on potassium for muscle contraction and nerve conduction
Cardiac muscles
Liver functions
Kidney tubules
Pancreas functions
When ______ levels are out of order, it is a slow process to correct it
Potassium
Sodium
Calcium
Magnesium
Hypokalemia S/S
Cardiac arrhythmias and skeletal muscle weakness
Cramps and Paralysis
Constipation and urinary retention
Increased reflexes and muscle weakness
Hypokalemia true vs apparent deficit
Apparent deficit is primarily a(n) ______________ while true deficit includes _________ and __________
intracellular shift; decreased intake; increased output
extracellular shift; increased intake; decreased output
Hyperkalemia S/S
Arrhythmias and weakness
Cramping and paralysis
Urine retention and bradycardia
Hyperkalemia true vs apparent deficit
Apparent deficit includes _________ lab specimens; while a true deficit includes _____________.
Hemolyzed; renal dsyfunction
Non Hemolyzed; renal dysfunction
Hemolyzed; decreased supplement intake
Non Hemolyzed; increased aldosterone secretion
Magnesium is primarily _________ and __% resides within the bone
Intracellular; 60%
Extracellular; 50%
Intracellular; 50%
Extracellular; 30%
Hypomagnesemia S/S
CNS effects and EKG changes
Weakness
Reflex increase
Arrhythmias
Hypomagnesemia causes
Renal wasting
Medication (loop diuretics)
Refeeding syndrome
GI loss
Hypermagnesemia symptoms are rare
True
False
______ is the most abundant extracellular anion
Sodium
Potassium
Magnesium
Chloride
Chloride is primarily regulated by the ___
Glomerulus
PCT
DCT
Collecting duct
Hyperchloremia indicates __________
NaCl infusion
Magnesium reabsorption
Gastric fluid loss
Vomiting
Hypochloremia S/S
Dehydration and vomiting
Loss of gastric fluid
NaCl infusion
Magnesium reabsorption
Bicarbonate is used to assess __________
acid-base balance
Bicarbonate increase leads to...
Bicarbonate decrease leads to...
Most prevalent cation - 99% found in the teeth
Function of calcium
Maintains cell integrity
Regulates endocrine secretory activity
Neuromuscular activity
Bone metabolism
Corrected Ca+ =
Serum Ca + 1 (5-albumin)
Serum Ca + 0.8 (4-albumin)
Serum Ca - 0.8 (4+albumin)
Hypocalcemia Acute S/S
Tetany and Parathesia
Muscle Cramps and Laryngeal spasms
Depression and Anxiety
Memory loss and Confusion
Hypocalcemia Chronic S/S
Depression and Anxiety
Tetany and Paresthesia
Memory loss and Confusion
Muscle Cramps and Laryngeal spasms
Fatigue, weakness, anorexia, depression, anxiety, cognitive dysfunction, vague abdominal pain, constipation, renal symptoms, acute pancreatitis are S/S of..
Hypocalcemia
Hypercalcemia
Hyponatremia
Hypernatremia
Hyperparathyroidism, Bone cancer, Toxic levels of Vitamin D and A, and thiazides are causes of
Hypercalcemia
Hypernatremia
Hyperkalemia
Hypokalemia
Vitamin D deficiency, Hyperphosphatemia, bisphosphonates causes
Hypocalcemia
Hypercalcemia
Hypokalemia
Hyperkalemia
Major intracellular anion mainly found in bones and soft tissue
Phosphorus
Sodium
Calcium
Potassium
Intestinal absorption of phosphorus _______ in presence of aluminum and calcium
Decrease
Increase
Confusion, Ataxia, Myalgia, Cardiac and respiratory failure are S/S of...
Hypophosphatemia
Hyperphosphatemia
Hypernatremia
Hyperkalemia
Causes of _______ are intracellular shifting, increased renal excretion, decreased intake
Hypophosphatemia
Hyperohosphatemia
N/V, Dehydration, Neuromuscular irritability, Red eye and pruritus are S/S of
Hyperphosphatemia
Hypophosphatemia
Hemolyzed samples need to be _______. typically in false elevation results of _________ and __________
(a)
BUN:SCr ratio >__ % indicated dehydration
20
15
25
40
