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Gametogenesis & GI Development

Total questions: 14

Worksheet time: 5mins

Name
Class
Date
1.

A research experiment tests a novel drug for heart failure in laboratory rats. Although the drug is effective in increasing cardiac output, it leads to sterility in the male rats. Semen analysis shows normal semen volume, pH, and motility. However, it is noted that the sperm count and androgen-binding protein are decreased.

Which of the following cell types is most likely responsible for these laboratory findings?

a)

Adrenal zona fasciculata cells

b)

Adrenal zona reticularis cells

c)

Leydig cells

d)

Sertoli cells

e)

Spermatogonia

2.

A pregnant woman comes to the clinic for prenatal care. The patient learns the sex of the fetus is male, based on the male external genitals observed on ultrasonography.

Which of the following hormones is most directly responsible for the external genitalia of her fetus?

a)

17-Hydroxyprogesterone

b)

Androstenedione

c)

Testosterone

d)

Dihydrotestosterone

e)

Follicle-stimulating hormone

3.

A 16-year-old girl comes to the clinic for a pregnancy test. She is tested with an assay that measures the presence of a hormone.

The detected hormone is most structurally similar to a hormone that has which of the following functions?

a)

Promotes rupture of the ovarian follicle during ovulation

b)

Promotes the release of cortisol from the adrenal cortex

c)

Promotes the release of thyroid-stimulating hormone from the anterior pituitary gland

d)

Stimulates milk production from mammary glands

e)

Stimulates uterine contractions during labor

4.

A 21-year-old woman is started on combined oral contraceptives for birth control. These contraceptives will decrease the amount of endogenous follicle-stimulating hormone produced.

Which of following is most likely to be immediately affected by this medication?

a)


Blastocyst implantation

b)


Estrogen concentration during follicular phase

c)

Fertilization of ovum

d)

Midcycle surge of luteinizing hormone

e)

Ovulation

5.

A nulliparous 28-year-old woman comes to the clinic seeking in vitro fertilization. She has been unable to conceive due to scarred fallopian tubes. She receives medications to stimulate oocyte development, and her oocytes are monitored as they develop into the follicular phase. She is then injected with an analog of gonadotropin-releasing hormone. An oocyte is then harvested using transvaginal needle aspiration and cultured in the laboratory for later incubation and fertilization.

At which of the following stages of meiosis will the harvested oocyte be arrested?

a)

Anaphase I

b)


Metaphase I

c)

Metaphase II

d)

Prophase I

e)

Prophase II

6.

A 22-year-old woman comes to her physician because of amenorrhea for 8 weeks. A pregnancy test is ordered.

Which of the following best describes the normal function of the hormone being tested?

a)

Induction of prolactin production

b)

Maintenance of the Graafian follicle

c)

Maintenance of the corpus luteum

d)

Maintenance of the placenta

e)

Preparation of the uterus for implantation

7.

A 5-day-old male presents to the emergency room with vomiting of green liquid and fussiness. He was born at term with an unremarkable birth history. Ultrasound reveals an inverse orientation of the superior mesenteric artery and vein.

Which of the following best describes the normal rotation of the affected structure during gastrointestinal development?

a)

A 270° counterclockwise rotation around the inferior mesenteric artery

b)

A 270° counterclockwise rotation around the superior mesenteric artery

c)

A 360° counterclockwise rotation around the inferior mesenteric artery

d)

A 360° counterclockwise rotation around the superior mesenteric artery

e)

A 90° counterclockwise rotation around the superior mesenteric artery

8.

Gastroschisis results from failure of the (a)   body folds to close.

9.

A neonate is born with abdominal contents herniating through the umbilical region. On exam, the loops of bowel are covered by a sac composed of peritoneum and amnion. Which of these is the most likely diagnosis.

a)

Gastroschisis

b)

Omphalocele

c)

Persistent vitelline duct

d)

Umbilical hernia

e)

Bladder exstrophy

10.

The midgut re-enters the abdominal cavity at week 10, completing a rotation of (a)   degrees.

11.

The primitive body cavity that will become the peritoneal cavity in the abdomen is called:

(a)  

12.

Based on embryonic development, which of the following structures is vascularized by branches of both the celiac and superior mesenteric arteries?

a)

Esophagus

b)

Duodenum

c)

Ileum

d)

Stomach

13.

Which of the following structures is intraperitoneal?

a)

Ascending colon

b)

Descending colon

c)

Duodenum

d)

Pancreas

e)

Stomach

14.

At week _, the midgut herniates out of the umbilical ring.

(a)