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Midterms OPTO MED

Total questions: 10

Worksheet time: 7mins

Name
Class
Date
1.

WIPE stands for

(a)  

2.

The LUN in LUNAD stands for

(a)  

3.

What type of drug enters the body but is inactive. It only becomes active Once it is turned into a metabolite.

(a)  

4.

If it enters the body → activates its effect → undergoes biotransformation → becomes inactive. It is therefore called a...

a)

prodrug

b)

metabolite

c)

functionalization

d)

conjugation

5.

Many metabolites undergo this phase when they are considered to be too lipophillc

a)

excretion

b)

functionalization

c)

synthetic reactions

d)

a synthetic reaction

6.

An efflux transporter that makes absorption erratic.

a)

alpha-1 acid glycoprotein

b)

p.glycoprotein

c)

DOPA decarboxylase

d)

glucuronide

7.

which of the following is / are true about glutathione

I. It is part of a synthetic reaction

II. It is part of functionalization

III. It is an antioxidant

Iv. Its main effect is skin whitening

a)

I and III

b)

II and IV

c)

I and II

d)

Ill and IV

8.

It hastens the process of oxidation

a)

cytochrome P-450

b)

VILEORA

c)

functionalization

d)

Metabolite

9.

which of the following drugs have the highest chance of absorption or distribution ?

a)

drugs that easily bind to alpha-1 acid glycoprotein

b)

drugs whose target organ is bone

c)

drugs who low first- pass hepatic metabolism

d)

drugs that are enteric-coated

10.

Which of the following drugs are most likely to be eliminated?

a)

A basic drug that is followed by another basic drug ("like dissolves like")

b)

A basic drug that is followed by an acidic drug

c)

Vitamin K

d)

drugs that are catalyzed by DOPA decarboxylase