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DNA Extraction and Analysis Quiz

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

Which of the following bases are classified as purines?

a)

Adenine and Cytosine

b)

Guanine and Thymine

c)

Adenine and Guanine

d)

Cytosine and Thymine

2.

In DNA extraction, the purpose of using isopropanol or ethanol is to:

a)

Break down proteins

b)

Precipitate DNA

c)

Dissolve lipids

d)

Separate RNA from DNA

3.

During phenol/chloroform extraction, nucleic acids are found in which layer after centrifugation?

a)

Organic (lower) layer

b)

Aqueous (upper) layer

c)

Interface layer

d)

Bound to phenol phase

4.

Which of the following differentiates DNA from RNA?

a)

DNA contains ribose sugar while RNA contains deoxyribose

b)

DNA is single-stranded while RNA is double-stranded

c)

DNA contains thymine while RNA contains uracil

d)

Both contain uracil as a nitrogenous base

5.

A researcher extracts DNA from banana using detergent, salt, and alcohol. The detergent function in this step is:

a)

To precipitate DNA

b)

To denature proteins

c)

To dissolve cell membranes by breaking lipids

d)

To stabilize DNA structure

6.

A student observes smeared DNA bands on agarose gel electrophoresis after extraction from blood. The most likely cause is:

a)

Contamination with RNA

b)

Overloading of the gel with DNA

c)

Incomplete protein removal

d)

All of the above

7.

Proteinase K is added during DNA extraction to:

a)

Digest polysaccharides

b)

Break down proteins and nucleases

c)

Precipitate DNA

d)

Enhance lipid dissolution

8.

A farmer in Egypt uses Bt cotton to reduce pesticide use. The gene responsible for pest resistance is inserted using:

a)

Lipid nanoparticles

b)

Agrobacterium-mediated transformation

c)

CRISPR-Cas9 editing

d)

Electroporation

9.

A patient’s tumor DNA is being sequenced to identify mutations for personalized therapy. The primary reason for DNA purification before sequencing is:

a)

To remove water

b)

To eliminate proteins and other contaminants that interfere with enzymes

c)

To increase DNA double helix stability

d)

To convert DNA to RNA for easier analysis

10.

In the development of COVID-19 vaccines, synthetic mRNA was produced from DNA templates. This demonstrates which principle of biotechnology?

a)

Reverse transcription from RNA to DNA

b)

Use of recombinant DNA to generate coding sequences

c)

Gene silencing using siRNA

d)

DNA replication by DNA polymerase III