NEW
Font size
WorksheetsAnalgesic Drugs and COX-1 Inhibitors
Total questions: 15
Worksheet time: 28mins
Which COX enzyme is primarily responsible for the production of prostaglandins that mediate inflammation?
COX-1
COX-2
COX-3
COX-4
What are the common contraindications for using NSAIDs?
Peptic ulcer disease, severe renal impairment, and hypersensitivity to NSAIDs.
Hypertension, diabetes mellitus, and asthma.
Chronic liver disease, pregnancy, and hyperlipidemia.
Gastroesophageal reflux disease, obesity, and anxiety disorders.
Which antipyretics are safe for infants?
Paracetamol (0 to 6 months)
Aspirin (0 to 6 months)
Ibuprofen (0 to 6 months)
Acetaminophen (6 months and older)
What is the difference between COX-1 and COX-2 enzymes?
COX-1 is primarily involved in inflammation, while COX-2 is involved in the production of protective gastric mucosa.
COX-1 inhibitors are safer for the stomach, while COX-2 inhibitors have more GI and bleeding side effects.
COX-1 is involved in the production of protective gastric mucosa, while COX-2 is primarily involved in inflammation.
COX-1 and COX-2 enzymes have no significant differences in their functions.
How do NSAIDs affect platelet function?
They enhance platelet aggregation, reducing the risk of bleeding.
They have no effect on platelet function.
They can inhibit platelet aggregation, which may prevent stroke but increase the risk of bleeding.
They only affect blood pressure and have no impact on platelets.
Which NSAIDs are considered safer for patients with cardiovascular risk, and what precautions should be taken when using them?
Naproxen – considered the safest NSAID for patients with cardiovascular risk.
Aspirin – always safe for cardiovascular patients.
Diclofenac – recommended for all patients regardless of risk.
Celecoxib – should be used without any precautions.
Which NSAIDs are most effective for managing dental pain and menstrual pain?
Ibuprofen
Aspirin
Mefenamic acid
Naproxen
Most effective NSAID for anti-inflammatory action?
ibuprofen
naproxen
celecoxib
aspirin
What are the potential risks associated with long-term use of NSAIDs?
Increased risk of gastrointestinal bleeding, cardiovascular events, and renal impairment.
Improved joint mobility and reduced pain.
Decreased risk of heart disease and stroke.
Enhanced kidney function and hydration.
Which NSAID is considered safe for use in patients with asthma?
Ibuprofen
Aspirin
Paracetamol
Naproxen
What are drugs with strong analgesic effects that are effective COX-1 inhibitors?
Ibuprofen
Acetaminophen
Ketorolac
Aspirin
What is the primary use of ibuprofen?
To relieve pain, reduce inflammation, and lower fever.
To treat bacterial infections.
To increase blood pressure.
To promote sleep.
What are the common side effects of nonsteroidal anti-inflammatory drugs (NSAIDs)?
Gastrointestinal issues, cardiovascular risks, kidney problems.
Increased energy levels and improved mood.
Weight gain and increased appetite.
Enhanced cognitive function and memory retention.
Why ibuprofen???
Ibuprofen is considered one of the safest drugs in the NSAID group.
Ibuprofen is not recommended for use during pregnancy.
Ibuprofen is only safe for adults and not for children.
Ibuprofen should not be used by breastfeeding mothers.
What is the mechanism of action of acetaminophen?
It inhibits the synthesis of prostaglandins in the central nervous system.
It blocks the reuptake of serotonin in the brain.
It acts as a non-selective COX inhibitor in peripheral tissues.
It enhances the release of endorphins in the spinal cord.
