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Pain Management Medications Part 2

Total questions: 28

Worksheet time: 14mins

Name
Class
Date
1.

What is the key brand name for Acetaminophen?

a)

Tylenol

b)

Motrin

c)

Celebrex

d)

Mobic

2.

Which drug is classified as an antidote and is used for acetaminophen overdose?

a)

Acetaminophen

b)

Acetylcysteine

c)

Celecoxib

d)

Ibuprofen

3.

Celecoxib belongs to which drug class?

a)

NSAID

b)

COX-2 inhibitor

c)

Triptan

d)

CGRP inhibitor

4.

Ibuprofen is typically used for _________

a)

Pain, inflammation

b)

Cough, cold

c)

Diabetes management

d)

Vision improvement

5.

What is the key brand name for Meloxicam?

a)

Mobic

b)

Celebrex

c)

Aleve

d)

Voltaren

6.

Which of the following drugs is NOT an NSAID?

a)

Diclofenac

b)

Indomethacin

c)

Sumatriptan

d)

Naproxen

7.

Ketorolac is typically used for:

a)

Migraine prophylaxis

b)

Short-term pain

c)

Pain, fever

d)

Acetaminophen overdose

8.

Lidocaine (patch) is classified as a _________.

a)

Topical anesthetic

b)

Antibiotic

c)

Antifungal

d)

Antihistamine

9.

Sumatriptan is used for which condition?

a)

Acute migraine

b)

Pain, inflammation

c)

Localised pain

d)

Migraine prophylaxis

10.

What is the key brand name for Rizatriptan?

a)

Maxalt

b)

Imitrex

c)

Zomig

d)

Relpax

11.

Erenumab is a ________ inhibitor used for migraine prophylaxis.

a)

CGRP

b)

MAO

c)

COX

d)

ACE

12.

Fremanezumab is used for:

a)

Pain, fever

b)

Migraine prophylaxis

c)

Short-term pain

d)

Acute migraine

13.

Match the following drugs to their key brand names:

a)

Voltaren

1.

Diclofenac

b)

Indocin

2.

Indomethacin

c)

Tylenol

3.

acetaminophen

d)

Emgality

4.

Galcanezumab

14.

Which drug is classified as a CGRP inhibitor and is used for migraine prophylaxis?

a)

Erenumab

b)

Ibuprofen

c)

Ketorolac

d)

Celecoxib

15.

What is the mechanism of action of Acetaminophen?

a)

A) Central COX inhibition leading to decreased pain and fever

b)

B) Inhibit COX-1/2 leading to decreased prostaglandins

c)

C) 5-HT (serotonin) agonists causing cranial vasoconstriction

d)

D) Na+-channel block causing local neuronal conduction block

16.

Which drug class inhibits COX-1/2 and decreases prostaglandins, leading to analgesic and anti-inflammatory effects?

a)

Acetaminophen

b)

NSAIDs (± COX-2)

c)

Triptans

d)

CGRP mAbs

17.

Triptans are 5-HT (serotonin) agonists that cause cranial vasoconstriction and decrease neuropeptide release.

a)

True

b)

False

18.

CGRP mAbs block CGRP ligand/receptor to prevent _________

a)

migraine cascade

b)

immune response

c)

blood clotting

d)

muscle contraction

19.

Topical lidocaine works by blocking ________ channels, leading to local neuronal conduction block.

a)

Na+ (sodium)

b)

K+ (potassium)

c)

Ca2+ (calcium)

d)

Cl- (chloride)

20.

Which of the following is a common side effect of NSAIDs?

a)

Dizziness

b)

Injection-site pain

c)

Dyspepsia/heartburn, increased BP, fluid retention

d)

Mild local rash

21.

Acetaminophen is generally well-tolerated at doses up to ______ per day.

a)

4 g/day

b)

2 g/day

c)

6 g/day

d)

8 g/day

22.

Which drug class is associated with dizziness as a common side effect?

a)

NSAIDs

b)

Triptans

c)

CGRP mAbs

d)

Lidocaine patch

23.

What is a serious risk associated with acetaminophen use at doses greater than 4 g/day or with alcohol?

a)

GI bleed

b)

Hepatotoxicity

c)

Myocardial infarction

d)

Anaphylaxis

24.

NSAIDs can cause GI bleed, ulcer, and CV thrombotic events, as well as ________ failure.

a)

renal

b)

hepatic

c)

pulmonary

d)

thyroid

25.

Which drug should be avoided in patients with ischemic heart disease or uncontrolled hypertension?

a)

NSAIDs

b)

Triptans

c)

Acetaminophen

d)

CGRP mAbs

26.

Alcohol and hepatotoxic drugs combined with acetaminophen can lead to ________ failure.

a)

liver

b)

kidney

c)

heart

d)

lung

27.

Antiplatelets or anticoagulants combined with NSAIDs increase the risk of ________.

a)

bleeding

b)

hypertension

c)

hypoglycemia

d)

constipation

28.

SSRIs, SNRIs, MAO-Is, or ergots combined with triptans can cause ________ syndrome.

a)

serotonin

b)

neuroleptic malignant

c)

Stevens-Johnson

d)

Reye