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Exploring Complex Genetics Concepts

Total questions: 20

Worksheet time: 22mins

Name
Class
Date
1.

Which type of mutation results in a change in a single nucleotide base in DNA?

a)

Frameshift mutation

b)

Point mutation

c)

Chromosomal mutation

d)

Duplication mutation

2.

In codominance, if a person inherits an allele for type A blood from one parent and an allele for type B blood from the other, what is their blood type?

a)

Type A

b)

Type B

c)

Type AB

d)

Type O

3.

Which of the following is an example of incomplete dominance?

a)

A red flower crossed with a white flower produces pink flowers

b)

A person with type AB blood

c)

A person with sickle cell anemia

d)

A person with type O blood

4.

Which genotype would result in type O blood?

a)

IAIA

b)

IAIB

c)

IBIB

d)

ii

5.

What is epistasis?

a)

When one gene masks or modifies the effect of another gene

b)

When both alleles are fully expressed in the phenotype

c)

When a gene is deleted from the chromosome

d)

When a gene is duplicated

6.

Which of the following is a genetic disorder in which blood cells are misshaped and cause blood clots?

a)

Down syndrome

b)

Sickle cell anemia

c)

Turner syndrome

d)

Klinefelter syndrome

7.

If a person with genotype IAiI^A i marries a person with genotype IBiI^B i , what is the probability that their child will have type O blood?

a)

0%

b)

25%

c)

50%

d)

75%

8.

Which of the following best describes codominance?

a)

One allele is completely dominant over the other

b)

Both alleles are expressed equally in the phenotype

c)

The phenotype is a blend of both alleles

d)

Neither allele is expressed

9.

Which of the following is an example of epistasis in animals?

a)

Labrador retriever coat color, where one gene determines pigment and another gene determines whether pigment is deposited

b)

Human blood types

c)

Sickle cell anemia

d)

Cystic fibrosis

10.

A mutation that results in a premature stop codon is called a:

a)

Missense mutation

b)

Nonsense mutation

c)

Silent mutation

d)

Frameshift mutation

11.

Which blood type is considered the universal donor?

a)

Type A

b)

Type B

c)

Type AB

d)

Type O

12.

In incomplete dominance, what would be the expected phenotype ratio in the offspring of two heterozygous parents ( Rr×RrRr \times Rr ) where RR is red and rr is white?

a)

1 red : 2 pink : 1 white

b)

3 red : 1 white

c)

1 red : 1 white

d)

2 red : 2 white

13.

Which of the following statements about gene expression is true?

a)

All genes are expressed at all times in every cell

b)

Gene expression can be turned on or off depending on the cell’s needs

c)

Only dominant genes are expressed

d)

Gene expression is not regulated

14.

Which of the following is NOT a possible human blood type?

a)

Type A

b)

Type B

c)

Type AB

d)

Type C

15.

A person with genotype IAIAI^A I^A has which blood type?

a)

Type A

b)

Type B

c)

Type AB

d)

Type O

16.

Which of the following best describes a frameshift mutation?

a)

A mutation that changes one amino acid to another

b)

A mutation that does not change the amino acid sequence

c)

A mutation caused by insertion or deletion of a nucleotide, altering the reading frame

d)

A mutation that results in a stop codon

17.

Which of the following is an example of codominance in humans?

a)

Sickle cell trait

b)

Blood type AB

c)

Cystic fibrosis

d)

Albinism

18.

Which of the following is true about genetic disorders?

a)

All genetic disorders are inherited in a dominant manner

b)

Some genetic disorders are caused by mutations in a single gene, while others involve multiple genes or chromosomes

c)

Genetic disorders cannot be caused by mutations

d)

All genetic disorders are curable

19.

In a dihybrid cross between two individuals who are heterozygous for both traits, the typical phenotypic ratio is?

a)

9:3:3:1

b)

12:3:1

c)

1:2:1

d)

3:1

20.

A micrograph in which pairs of homologous chromosomes are arranged in decreasing size is called a?

a)

prokaryote

b)

eukaryote

c)

karyotype

d)

pedigree