WorksheetsInternal Solution Preparation
Total questions: 18
Worksheet time: 9mins
What is the defining characteristic of a solution?
It is a biphasic liquid mixture.
It is a homogeneous mixture of two or more components.
It always contains a solid suspended in a liquid.
It is synonymous with any liquid dosage form.
According to the BP descriptive terms, a solute described as "Freely soluble" requires how many parts of solvent for one part of solute?
Less than 1 part
From 1 to 10 parts
From 10 to 30 parts
From 30 to 100 parts
What is the most common vehicle used in pharmaceutical solutions due to its cost, availability, and safety?
Alcohol
Glycerol
Syrup
Water
Which type of water must be pyrogen-free and sterilized immediately after preparation?
Potable Water
Purified Water
Water for Injections
Aromatic Waters
Syrup BP is defined as a solution of what concentration of sucrose in water?
10%
33.3%
50%
66.7%
Which vehicle is a viscous liquid, miscible with both water and alcohol, and can act as a stabilizer, sweetener, and preservative?
Propylene Glycol
Glycerol (Glycerin)
Fractionated Coconut Oil
Ethyl Alcohol
The principle of "like dissolves like" is most directly related to which factor affecting solubility?
pH
Particle Size
Polarity
Temperature
Which method for increasing solubility involves the use of surfactants like polysorbates?
Co-solvency
Agitation
Solubilization
Buffering
What is the primary function of a preservative in a solution?
To prevent oxidative degradation
To increase the dissolution rate
To prevent bacterial and fungal growth
To make the product iso-osmotic with tissue fluids
Which additive is used to prevent variations in pH during the use or storage of a solution?
Antioxidant
Buffer
Isotonic Modifier
Sweetening Agent
Elixirs are characterized as which of the following?
Sweetened, hydro-alcoholic liquids
Saturated solutions of volatile oil
Viscous, oil-based solutions
Aqueous suspensions of diffusible solids
What is the typical alcohol content range in elixirs?
0.1 - 1%
2 - 40%
50 - 70%
90 - 100%
A "Draught" is best described as what?
A liquid preparation containing indiffusible solids.
A sugar-free solvent for diabetic patients.
A liquid mixture formulated as a single, large dose.
Another name for any oral solution.
Oral drops are seldom manufactured today except for which patient population?
Geriatric patients
Paediatric patients
Diabetic patients
Patients with heart conditions
Why are amber glass bottles often preferred for packaging oral solutions?
They are unbreakable.
They are the cheapest option.
They protect light-sensitive medications from degradation.
They are required for all controlled medicines.
Which of the following is a "Sugar-Free" solvent alternative to Syrup BP?
Sucrose
Glycerol
Sorbitol
Chloroform Water
The term "Sparingly soluble" indicates that one part of solute requires how many parts of solvent?
1-10 parts
10-30 parts
30-100 parts
100-1000 parts
Which factor affecting solubility is improved by reducing particle size to increase surface area?
Polarity
pH
Dissolution Rate
Saturation Point
