WorksheetsWorksheet Questions Extraction
Total questions: 150
Worksheet time: 1hrs 15mins
What is the Carr's index of good flow powder property
5-15
12-16
18-21
28-35
Which microorganism is involved in the assay of Rifampicin
Bacillus subtilis
Micrococcus luteus
Bacillus pumilus
Bacillus cereus
Which percentage of dextrose is isotonic with the blood plasma
5%
10%
15%
20%
What is the biological source of Alexandrian Senna
Cassia aungustifolia
Cassia acutifolia
Cassia Bravifolia
Cassia Nerifolia
HLB of SPAN and TWEEN surfactants may be obtained from which of the following equations
HLB = E/5
HLB = (E+P)/5
HLB = 20 (1 − S/A)
HLB = (hydrophilic group numbers) − (lipophilic group numbers) + 7
If the given drug is absorbed by passive what will be its absorption kinetics
Zero Order
First Order
Second order
Pseudo-zero Order
Which of the following is delayed type of hypersensitivity reaction
Arthus reaction
Penicillin sensitivity
Tuberculin sensitivity
ABO incompatibility
Which of the following is NOT suitable as a post-coital contraceptive
Levonorgestrel 1.5 mg
Ulipristal acetate 30 mg
Mifepristone 10-25 mg
Mestranol 1.5 mg
Which of the following properties are characteristics of tannins: P) They give a precipitate with alkaloids; Q) They give a yellow or bluish red color with iron(III) chloride; R) They transform hide into leather; S) They give a pale-pink precipitate with iodine
P, Q, S
P and Q
P and R
Only Q
Adverse drug event reporting is the responsibility of all of the following EXCEPT
Pharmacist and physician
Manufacturer
Consumer
Regulatory authorities
Time dependent dilatant behavior is known as
Thixotrophy
Rheopexy
Rheomalaxis
Plastic
Chairman of DTAB is
Health minister of India
Director general of Health services
Drug controller of India
President of AICTE
Plasmodesmata is
Lignified element
Vascular element
Very fine protoplasmic thread
None
Efficiency of drug is checked in modest population in
Clinical trial-phase1
Clinical trial-phase2
Clinical trial-phase3
Clinical trial-phase4
Which of the following statements is correct for gram positive bacteria
Cell wall has a thin peptidoglycan layer
Cell wall lipid content is very low and smaller volume of periplasm
Lipopolysaccharide layer is present
Teichoic acid is present
The terms upper consulate temperature and lower consulate temperature are related to which phenomenon
Cloud point
Critical solution temperature
Kraft point
Phase inversion
Match the alkaloid Pilocarpine with its synthesis precursor
Nucleotide
Tryptophan
Histidine
Acetate derived
Match the alkaloid Connine with its synthesis precursor
Nucleotide
Tryptophan
Histidine
Acetate derived
Match the alkaloid Caffeine with its synthesis precursor
Nucleotide
Tryptophan
Histidine
Acetate derived
Match the alkaloid Yohimbine with its synthesis precursor
Nucleotide
Tryptophan
Histidine
Acetate derived
Which one of the following is a solid dosage form excipient which can play the role of a diluent, a disintegrant, a glidant, a lubricant and a pore/channel former
Lactose
Microcrystalline cellulose
Ethyl cellulose
Eudragit RL 100
What is the required floor area for running a pharmacy for wholesale or distribution
6 sq meters
10 sq meters
15 sq meters
30 sq meters
Bioavailability differences among drug's oral formulations are most likely to occur if it
Is freely water soluble
Is incompletely absorbed
Is completely absorbed
Undergoes little first-pass metabolism
Match the drug Ergotamine with its receptor profile
5-HT2 antagonist
5-HT1 partial agonist/antagonist
5-HT3 antagonist
5-HT1D agonist
Match the drug Ondansetron with its receptor profile
5-HT2 antagonist
5-HT1 partial agonist/antagonist
5-HT3 antagonist
5-HT1D agonist
Match the drug Sumatriptan with its receptor profile
5-HT2 antagonist
5-HT1 partial agonist/antagonist
5-HT3 antagonist
5-HT1D agonist
Match the drug Ketanserin with its receptor profile
5-HT2 antagonist
5-HT1 partial agonist/antagonist
5-HT3 antagonist
5-HT1D agonist
What strategy of drug design is frequently used on complex lead compounds derived from natural products
Extension
Simplication
Rigidication
Conformational block
Which type of photon detector is commonly microfabricated into arrays of 500 or More individual detectors
Photocell
Phototube
Photomultiplier tube
Photodiode
Which of the following is a phse II drug metabolism reaction associated with genetic polymorphism
Glucuronidation
Acetylation
Reduction
Glutathione conjugation
A gram-negative diplococcus associated with urinary tract infection , pelvic inflammatory disease and conjunctivitis, meningitis is
Neissria gonorrhoeae
Chlamdia Trachomatis
Hemophilus influenza
Streptococcus pneumoniae
Pregnancy test kits are designed to detect
Estrogen
Human chorionic gonadotropin
Follicle-stimulating hormone
Luteinizing hormone
Drug Z is a depolarizing neuromuscular blocking agent effective for the treatment of pinworm. Identify drug Z
Phyrantel
Paramomycin
Integrase
Protease
Methenamine used for UTI is a prodrug. How and to what is is converted into
At low pH of Urine, to formaldehye
At high pH of urine, to aminosalicylic acid
At low pH of Urine, to amonosalicylic acid
At high pH of urine,to formaldehye
The correct order for the basic features of a mass spectrometer is
Acceleration, deflection, detection, ionization
Ionization ,Acceleration, deflection, detection
Acceleration, ionization, deflection, detection
Acceleration, deflection, ionization, detection
Match the following enzymes/protein with specific functions in DNA replication: Helicases — select the correct function
Processive unwinding of DNA
Seals the single strand
Relieves torsional strain
Initates synthesis of RNA Primers
Match the following enzymes/protein with specific functions in DNA replication: DNA Primses — select the correct function
Processive unwinding of DNA
Seals the single strand
Relieves torsional strain
Initates synthesis of RNA Primers
Match the following enzymes/protein with specific functions in DNA replication: DNA ligases — select the correct function
Processive unwinding of DNA
Seals the single strand
Relieves torsional strain
Initates synthesis of RNA Primers
Match the following enzymes/protein with specific functions in DNA replication: Topoisomerases — select the correct function
Processive unwinding of DNA
Seals the single strand
Relieves torsional strain
Initates synthesis of RNA Primers
Which is the first line drug for the treatment of generalized seizures
Valproic acid
Anhydrotetracycline
Carbamazepine
Doxycycline
Tetracycline in basic solution is usstable and forms which product
Epitthracycline
Anhydrotetracycline
Isotetracycline
Doxycycline
The location of the blood-brain barrier is considered to be
At the level of the brain capillaries
At the level of gila
At the level of neorons
At the level of dendrites
The following drug metabolizing reaction in entirely non-microsomal:
Glucuronide conjugation
Acetylation
Oxidation
Reduction
Which of the following methods is used to determine whether a process functions properly for its intended use
Capacity
Inspection
Validation
Design Review
Match product, source and plant part form which they areobtained: Bacosides — select the correct source and plant part
Aciacia catechu, Herb
Rubiatctorium, Leaf
Bacopamonnieri, Herb
Lawsoniainternis, Stem
Match product, source and plant part form which they areobtained: Cutch — select the correct source and plant part
Aciacia catechu, Stem
Rubiatctorium, Root
Bacopamonnieri, Leaf
Lawsoniainternis, Herb
Match product, source and plant part form which they areobtained: Henna — select the correct source and plant part
Aciacia catechu, Root
Rubiatctorium, Stem
Bacopamonnieri, Herb
Lawsoniainternis, Leaf
Match product, source and plant part form which they areobtained: Alizarm — select the correct source and plant part
Aciacia catechu, Leaf
Rubiatctorium, Root
Bacopamonnieri, Stem
Lawsoniainternis, Herb
What is the significance of term overfill
It is similar to overage
It is the excess volume to be field in containers as vials, ampoules to avoid loss by degradation
It is the excess filing of container as vials, ampoules to avoid the loss during case
It is violation of packaging regulation as per GMP
Identity the false statements
A characteristics of drugs eliminated by zero order kinetic process is that the half –life is not constrains
The plasma drug concertation versus time curve for a drug eliminated by zero order kinetics linear
A fundamental characteristics of all first order pharmacogenetics processes is that the rate of the process is proportional to drug concentration
A characteristics of absorption by lipid diffusion is its saturability at high drug concentrations
2’, 3’-Didehydro-3’-deoxy thymidine is the chemical name of which of following antiviral agents
Didenosine
Zidovudine
Stavudine
Zalcitabine
Oseltamivir is antiviral drug. It produces its action by inhibiting which enzymes
DNA polymerase
Neuraminidase
Praziquantel
Ivermectin
In NMR spectrum, a signal is observed as triplet. What will be the ratio of relative peak areas in this signal
1:1:1
1:2:1
1:3:1
1:4:1
Which problem can arise if the material to be compressed into tablet tends to adhere to die walls
Picking
Sticking
Capping
Marbling
What is the half life of Tc-99m
66 years
66 hours
6 hours
60 minutes
Eudragits are
Phthalate polymers
Cellulose polymers
Acrylate polymers
Amide polymers
Drugs (price control) order 1995 and related orders form time to time are enforeced by
NPPA
CSIR
DBT
ICMR
Match the drugs with plant from which they are isolated and their families — For Artemisinin, choose the correct plant and family from the lists: plants (Periwinkle; May apple; Sweet wormwood; Maxican wild yam) and families (Dioscoreaceae; Apocynaceae; Berberidaceae; Asteraceae)
Sweet wormwood; Asteraceae
Periwinkle; Apocynaceae
May apple; Berberidaceae
Maxican wild yam; Dioscoreaceae
Match the drugs with plant from which they are isolated and their families — For Diosgenin, choose the correct plant and family from the lists: plants (Periwinkle; May apple; Sweet wormwood; Maxican wild yam) and families (Dioscoreaceae; Apocynaceae; Berberidaceae; Asteraceae)
Periwinkle; Apocynaceae
Maxican wild yam; Dioscoreaceae
May apple; Berberidaceae
Sweet wormwood; Asteraceae
Match the drugs with plant from which they are isolated and their families — For Etoposide, choose the correct plant and family from the lists: plants (Periwinkle; May apple; Sweet wormwood; Maxican wild yam) and families (Dioscoreaceae; Apocynaceae; Berberidaceae; Asteraceae)
Sweet wormwood; Asteraceae
Maxican wild yam; Dioscoreaceae
May apple; Berberidaceae
Periwinkle; Apocynaceae
Match the drugs with plant from which they are isolated and their families — For Vinblastine and Vincristine, choose the correct plant and family from the lists: plants (Periwinkle; May apple; Sweet wormwood; Maxican wild yam) and families (Dioscoreaceae; Apocynaceae; Berberidaceae; Asteraceae)
May apple; Berberidaceae
Periwinkle; Apocynaceae
Sweet wormwood; Asteraceae
Maxican wild yam; Dioscoreaceae
Which of the following is an irreversible phenomenon related to stability of emulsion
Craking
Creaming
Coalescence
Flocculation
If a drug is highly bound to plasma proteins, what might be its reason or consequence
It most likely carried by α-glycorprotien
It has a high renal clearance
It has a large Vd
It is a likely candidate for drug interactions
In order to make a generic substitution ; a pharmacist must do
Notify the patient of the substitution
Charge the same or lower price for the generic
Place the brand name on the label and write “substitute for”
Obtain the physician’s consent to substitute the product
Which of the following groups can form ionic interactions and also act as a hydrogen bond acceptor
Hydroxyl group (OH)
Carboxylate group (RCOO)
Aminononium group (RNH3+)
Ketone (C=O)
Which of the following drug does not give pink colour with ruthenium red
Agar
Guar gum
Pectin
Isabgol
The IUPAC name, 4-Amino-N(5,6-dimethoxy-4-pyrimidinyl) benzenesulfonamide belong to which generic drug
Sulfadimidine
Sulfadoxine
Sulfalene
Sufamerazine
Method of inspections used to determine the absorption rate constants. It assumes that (P) Ka is at least five time grater activities (Q) Absorption in complete (i.e. >95% complete) at the time of peak concentration (R) Both Absorption and elimination are first order processes
P and Q
Q and R
Q and R
P and R
The clinical trial registry in India is maintained by
World health organization, Delhi
Indian council of medical research, New Delhi
Institute of Clinical Research, New Delhi
Central drugs standard control Organization, New Delhi
What is the correct order for unsaturation in following fatty acids (1) Palmitoleic Acid (2) Linolenic (3) Linoleic acid (4) Arachidonic acid
1>2>3>4
3>4>2>1
4>3>2>1
4>2>3>1
Which of the following is an example of Diaz onium ion
CH3 N3
CH N•
H N-NH •
None of these
Which term describes ‘The degree to which a set of inherent properties of a product system, of process fulfils requirements, the best’
Standard
Quality
Quality objective
State of control
What will be AUC value of lidocaine if the administered dose is 0.2 g and the total body clearance is 45 L/h
4.44 h·mg/L
0.0044 h·mg/L
9.00 h·gm/L
9000 h·mg/L
Toluene is converted of which compound in presence of CrO3 with acetic anhydride
Benzyl alcohol
Benzaldehyde
Benzoic acid
Benzoin
Select the correct mode of action for Artemisinin from the following: (P) Inhibition of parasite mitochondrial electron Transport (Q) Inhibition of heme polymerase (R) Generation of oxygen and carbon- centered radicals (S) Inhibition of dihydrofolate reductase
Inhibition of parasite mitochondrial electron Transport
Inhibition of heme polymerase
Generation of oxygen and carbon- centered radicals
Inhibition of dihydrofolate reductase
Select the correct mode of action for Pyrimethamine from the following: (P) Inhibition of parasite mitochondrial electron Transport (Q) Inhibition of heme polymerase (R) Generation of oxygen and carbon- centered radicals (S) Inhibition of dihydrofolate reductase
Inhibition of parasite mitochondrial electron Transport
Inhibition of heme polymerase
Generation of oxygen and carbon- centered radicals
Inhibition of dihydrofolate reductase
Select the correct mode of action for Quinine from the following: (P) Inhibition of parasite mitochondrial electron Transport (Q) Inhibition of heme polymerase (R) Generation of oxygen and carbon- centered radicals (S) Inhibition of dihydrofolate reductase
Inhibition of parasite mitochondrial electron Transport
Inhibition of heme polymerase
Generation of oxygen and carbon- centered radicals
Inhibition of dihydrofolate reductase
Select the correct mode of action for Atovaquone/Proguanil from the following: (P) Inhibition of parasite mitochondrial electron Transport (Q) Inhibition of heme polymerase (R) Generation of oxygen and carbon- centered radicals (S) Inhibition of dihydrofolate reductase
Inhibition of parasite mitochondrial electron Transport
Inhibition of heme polymerase
Generation of oxygen and carbon- centered radicals
Inhibition of dihydrofolate reductase
Methyl ether of erythromycin is
Clarithromycin
Dirithromycin
Azithromycin
Mithramycin
Ebullioscopic method is based on which of the following observation
Freezing point depression
Boiling point elevation
Osmotic pressure change
None of the above
How many fundamental vibrations can be expected for C2H5Cl
7
11
14
18
Which of the antibodies provide passive immunity to newborn baby
IgG
IgM
IgA
IgE
Increased number of mitosis may be present in the following tissue EXCEPT
Bone marrow cells
Nails
Hepatocytes
Intestinal Cells
To which chemical class the vinca alkaloids belong
Tropane
Indole
Tryptopha
Purine
An antibiotic that resembles the 3' end of a charged tRNA molecule is
Streptomycin
Vancamycin
Puromycin
Tetracycline
If the cohesive forces between similar molecules are less than the adhesive forces between dissimilar molecules, a deviation in Raoult’s law is observed. Here which deviation will be seen
Positive
Negative
Absent
Either positive or negative
Phenylalanine, a precursor of most of the phenolics in higher plants, is a product of which one of the following pathways
Shikimic acid pathway
Malonic acid pathway
Mevalonic acid pathway
Methylerythritol pathway
Within how many days a pharmacist should dispense diluted aqueous mixtures
7 days
14 days
21 days
30 days
What molecular feature is penicillin G is said to mimic
Disaccharide of N-acetylmuranicanid N- acetylglucosamine
N-acetylneuraminic acid
The pentapeptide moiety of five glycine units
The dipeptide moiety D-ala-D-Ala
If a drug is known to be distributed into total body water, how many milligrams are needed to obtain an initial plasma level of 5 mg/L in a patient weighting 70 kg
210
150
50
35
What does ‘pharmacokinetic compartment’ mean
Part of the body water which is located is the vascular system
Total body water
Plasma, intracellular fluid, together, anatomical water compartments where drug is absorbed
Part of the body water in which the change of a drug concentration has the same kinetics
The resistance to macrolide antibiotics by gram positive organism is developed due to
Decreases uptake of antibiotics
Synthesis of esterase enzyme that hydrolyzes lactone ring of macrolide
Methylation of 50S subunit at the antibiotic binding site
Increased metabolism of antibiotic
The ethanolic solution contaminated with benzene showed absorbance of 0.69 at 260 nm in a 2 cm cell. If the molar absorptivity of benzene in ethanol is 230 M^{-1} cm^{-1}, what is the concentration of benzene in the solution
0.003 M
0.0015 M
0.001 M
0.015 M
The most effective agent for treating psychosis would be
Buspirone
Sertraline
Dextroamphetamine
Olanzapine
TGA is regulatory body of which country
Europe
Australia
Canada
UK
Which prostaglandins have a keto function at C-9 and a α-Hydroxyl group at C-11 in prostanoic acid backbone
PGA
PGI
PGE
PGF
When morphine is heated at 140°C under pressure, with strong HCL, it converts into
Morphinone
Apomorphine
Codeine
Oxymorphine
All of the following are gram-negative rods EXCEPT
Clostridium
Escherichia
Salmonella
Shigella
The cells which secrets male sexhormone testosterone are
Crypts of lieberkuhn
Escherichia
Salmonella
Shigella
If QA and QC are compared
Both are literally the same
QA is a higher activity in the management hierarchy
QA is a higher activity in the management hierarchy
QA is a done by the production person and QC is done by analyst
Bio availability of drug refers to (P) The ratio of drug excreted unchanged in urine to that excreted as metabolites (Q) Fraction of the drug reaching the target to produce the action (R) The length of time an administered drug is available for action (S) Percentages of administered dose that reaches systemic circulation in the unchanged form
Only P
Q and R
R and S
Only S
Following intravenous administration, drugs are distributed fastest to
The skin, kidney, and brain
The liver, kidney, and brain
The liver, adipose, and brain
The liver, kidney, and adipose
Which of the following agents act as hypoglycemic as ATP sensitive potassium channel blocker
Mitiglinide
Pioglitazone
Liraglutide
Sitagliptin
Carbilide shows stongs IR absorption in which of the following range in cm⁻¹
3200-3600
1640-1690
1000-1300
2210-2260
Match the drugs with their adverse effects — Cyclophosphamide
Pulmonary fibrosis
Nephrotoxicity, ototoxicity
Acute hemorrhage cystitis
Cardiotoxicity
Match the drugs with their adverse effects — Doxorubicin
Pulmonary fibrosis
Nephrotoxicity, ototoxicity
Acute hemorrhage cystitis
Cardiotoxicity
Match the drugs with their adverse effects — Bleomycin
Pulmonary fibrosis
Nephrotoxicity, ototoxicity
Acute hemorrhage cystitis
Cardiotoxicity
Match the drugs with their adverse effects — Cisplatin
Pulmonary fibrosis
Nephrotoxicity, ototoxicity
Acute hemorrhage cystitis
Cardiotoxicity
Which one of the following technique is used to determine glass transition temperature
X-ray diffractometry
Raman spectroscopy
Differential scanning calorimetry
Atomic forced microscopy
Match the schedules with the particulars they describe — Schedule T
Standards for patent or proprietary medicines
Requirements/ guidelines to import &/or manufactures new Drug
GMP practices for Ayurvedic, siddha & Unani medicines
Particulars to be shown in the manufacturing records
Match the schedules with the particulars they describe — Schedule U
Standards for patent or proprietary medicines
Requirements/ guidelines to import &/or manufactures new Drug
GMP practices for Ayurvedic, siddha & Unani medicines
Particulars to be shown in the manufacturing records
Match the schedules with the particulars they describe — Schedule V
Standards for patent or proprietary medicines
Requirements/ guidelines to import &/or manufactures new Drug
GMP practices for Ayurvedic, siddha & Unani medicines
Particulars to be shown in the manufacturing records
Match the schedules with the particulars they describe — Schedule Y
Standards for patent or proprietary medicines
Requirements/ guidelines to import &/or manufactures new Drug
GMP practices for Ayurvedic, siddha & Unani medicines
Particulars to be shown in the manufacturing records
Which of the following UV rays cause cancer
UVA
UVB
UVC
All of the above
Which are the types of antibodies involved in hypersensitivity reactions
IgG and IgD
IgG and IgM
IgD and IgA
IgM and IgD
The term used to describe unequal distribution of colour on a tablet is
Chipping
Mottling
Lamination
Double impress
Why acetyl chloride undergoes nucleophilic substitution at a faster rate than methyl acetate
The ester is more sterically hindered than the acid chloride
The chloride ion is a better leaving group than methoxide
The acid chloride is more sterically hindered than the ester
The methoxide ion is a better leaving group than chloride
The key concept of Total Quality Managements (TQM) is
Total control of all quality related activities
Commitment of all employees to quality improvement and having team meetings
Top management’s direct involvement
The Introduction ot the ISO 9000 Series
A drug of low water solubility when given orally is absorbed up to 90% of the administered dose. The drug belongs to which class according to BCS classification
Class IV
Class III
Class II
Class I
Which of the following is NOT a component of evaporator
Heat exchange
Vacuum separator
Condenser
Cyclone separator
In parkinson’s disease, there is a predominant loss of dopaminergic neurons
Substantia
Cerebellar
Cerebral cortex
Locus ceruleus
At equilibrium the receptor occupancy is related to drug concentration by
Henderson-Hasselbach equation
Hill-Langmuir equation
Lineweaver-Burk equation
Langmuir adsorption isotherm
Which method is not suitable to calculate area under the curve
Least square method
Weighing and planimetry
Trapezoid rule
Integration of curve
OROS is a technology developed for/as
Oral release rapid onset system
Orally rapid disintegrating tablets
Osmotic controlled oral drug delivery system
Transdermal drug delivery system
Match the events in tablet manufacturing process with the effects found in tables: Rapid drying of coated tablets after coating. Choose the correct effect from: Increased disintegration time, Weight variation, Orange peel, Blistering
Increased disintegration time
Weight variation
Orange peel
Blistering
Match the events in tablet manufacturing process with the effects found in tables: Use to highly viscous solution. Choose the correct effect from: Increased disintegration time, Weight variation, Orange peel, Blistering
Increased disintegration time
Weight variation
Orange peel
Blistering
Match the events in tablet manufacturing process with the effects found in tables: Improper feed rate form hopper. Choose the correct effect from: Increased disintegration time, Weight variation, Orange peel, Blistering
Increased disintegration time
Weight variation
Orange peel
Blistering
Match the events in tablet manufacturing process with the effects found in tables: Excessive compression force. Choose the correct effect from: Increased disintegration time, Weight variation, Orange peel, Blistering
Increased disintegration time
Weight variation
Orange peel
Blistering
At pH 5, the ratio of the protonated to unprotonated forms of morphine pKa 7 would be
1:100
1:10
10:1
100:1
What structure is formed if the acyl side chain of penicillin is hydrolysed
Penicellenic acids
Penillic acids
7-Aminopenicillanic acid
6-Aminopenicillanic acid
The clinical trial is being conducted with 1500 volunteers which may spans on period of 2 years as per protocol. The clinical trial is in which phase
Phase 1
Phase 2
Phase 3
Phase 4
Which of the following drug has not undergone a clinical trial for its use to decrease intracranial pressure
Dideoxyinosine
Zidovudine
Acetazolamide
Nicotine
Colloidal depression have which type of rheology
Newtonian
Pseudoplastic
Non-Newtonian
Dilatant
Which of the reactive oxygen species is most dangerous to cells
Singlet oxygen
Hydroxyl radical
Superoxide
Peroxide
The Gibb’s Phase rule
Holds only for systems with more than components
Predicts that a maximum of three phase can exits in one components system
Does not count phase compositions as intensive variables
Does not count pressure and temperature as intensive variables
Nerve impulse from the cochlea arrive first in which region of the brain
Auditory cortex
Thalamus
Medulla oblongata
Inferior colliculus
The product of a Michael reaction of a ketone enolate to ana, b-unsaturated ketone is............And addition reaction occurs in a/an
1,5-deketone; 1,4 fashion
α-substituted acetate; 1,2 fashion
β-hydroxy keto; 1,3 - fashion
α, β - keto ester; 1,5 –fashion
Which of the following is a drug considered as potassium sparing diuretic
Trimatrine
Chlorthiazide
Mannitol
Furosemide
Which of the reagent from the given can be used to protect ketone group
Acidic methanol
Basic methanol
Methanol + KCN
Phenobarbitone
Which of the following drugs causes less inhibition or REM sleep
Zolpidem
Ethanol
Lorazepam
Phenobarbitone
The starting materials for synthesis of sulfamethoxazole are
4-Aminobenzene-1-sulfonyl amide + 3-chloro-5-methyl isoxazole
4-Aminobenzene-1-sulfonyl amide + 3-amino-5-methyl isoxazole
4-Aminobenzene-1-sulfonyl amide + 3-amino-5-methyl isoxazole
4-Aminobenzene-1-sulfonyl amide + 5-chloro-5-methyl isoxazole
Match the following plant product with their chemical class: b-amyrin — choose the correct class.
Alkaloid secondary alcohol
Alkaloid, phenol
Triterpene, secondary alcohol
Acyclic triterpene, polyene
Match the following plant product with their chemical class: Squalene — choose the correct class.
Alkaloid secondary alcohol
Alkaloid, phenol
Triterpene, secondary alcohol
Acyclic triterpene, polyene
Match the following plant product with their chemical class: Morphine — choose the correct class.
Alkaloid secondary alcohol
Alkaloid, phenol
Triterpene, secondary alcohol
Acyclic triterpene, polyene
Match the following plant product with their chemical class: Ephedrine — choose the correct class.
Alkaloid secondary alcohol
Alkaloid, phenol
Triterpene, secondary alcohol
Acyclic triterpene, polyene
All of the following except one are subject to therapeutic drug monitoring. Which one is the exception?
Phenytoin
Lithium
Gentamicin
Losartan
Thiamine deficiency causes decreased energy production because
It is required for the process of transamination
It is a co‑factor in oxidative reduction
It is a co‑enzyme for transketolase in the pentose phosphate pathway
It is a co‑enzyme for pyruvate dehydrogenase and alpha‑ketoglutarate dehydrogenase
Which of the following drugs are often found in both prescription and over‑the‑counter nasal decongestants?
Alpha 2 agonists
Alpha 1 agonists
Alpha 1 antagonists
Beta 2 agonists
What is the surface tension of water at 25°C?
58 dyne/cm
68 dyne/cm
72 dyne/cm
82 dyne/cm
Acridine and xanthene rings are related to each other in that
Xanthene is oxygen isoster of acridine
Acridine is oxygen isoster of xanthene
Xanthene is nitrogen isoster of acridine
Xanthene is sulfur isoster as acridine
