WorksheetsPRCBB_2MT-P5
Total questions: 124
Worksheet time: 1hrs 2mins
Name
Class
Date
1.
The antigens and antibodies are similar in serologic properties but are not genetically related
a)
Landsteiner Wiener Blood Group System
b)
Lewis Blood Group System
c)
MNSs Blood Group System
d)
P Blood Group
2.
Antibodies of this blood group can mimic the reactivity of anti-D
a)
Landsteiner Wiener Blood Group System
b)
Lewis Blood Group System
c)
MNSs Blood Group System
d)
P Blood Group
3.
antigens are denatured with 0.2 m DTT treatment while D antigens are unaffected
a)
Landsteiner Wiener Blood Group System
b)
Lewis Blood Group System
c)
MNSs Blood Group System
d)
P Blood Group
4.
Anti-D will react only with the Rh-positive cord cells whereas the LW antibodies will react with all cord cells tested, regardless of Rh type
a)
Landsteiner Wiener Blood Group System
b)
Lewis Blood Group System
c)
MNSs Blood Group System
d)
P Blood Group
5.
ABO, D, Lewis, H
a)
Glycosyltransferases
b)
Structural relationship to red cell
c)
Transport proteins
d)
Complement pathway
6.
MNSs, Diego, Gerbich
a)
Glycosyltransferases
b)
Structural relationship to red cell
c)
Transport proteins
d)
Complement pathway
7.
Rh, Kidd, Diego, Colton
a)
Glycosyltransferases
b)
Structural relationship to red cell
c)
Transport proteins
d)
Complement pathway
8.
Chido/Rogers, Cromer, Knops
a)
Glycosyltransferases
b)
Structural relationship to red cell
c)
Transport proteins
d)
Complement pathway
9.
Lutheran, Xg, Lewis, Indian
a)
Adhesion molecule
b)
Microbial receptors
c)
Biologic receptors
10.
MNSs, Duffy, P, Lewis, Cromer
a)
Adhesion molecule
b)
Microbial receptors
c)
Biologic receptors
11.
DUffy, Knops, Indian
a)
Adhesion molecule
b)
Microbial receptors
c)
Biologic receptors
12.
Glycosyltransferases
a)
ABO, D, Lewis H
b)
MNSs, Diego, Gerbich
c)
Rh, Kidd, Diego, Colton
d)
Chido or Rogers, Cromer, Knops
13.
Structural relationship to Red cell
a)
ABO, D, Lewis H
b)
MNSs, Diego, Gerbich
c)
Rh, Kidd, Diego, Colton
d)
Chido or Rogers, Cromer, Knops
14.
Transport proteins
a)
ABO, D, Lewis H
b)
MNSs, Diego, Gerbich
c)
Rh, Kidd, Diego, Colton
d)
Chido or Rogers, Cromer, Knops
15.
Complement pathway molecule
a)
ABO, D, Lewis H
b)
MNSs, Diego, Gerbich
c)
Rh, Kidd, Diego, Colton
d)
Chido or Rogers, Cromer, Knops
16.
Adhesion molecule
a)
Lutheran, Xg, Lewis, Indian
b)
MNSs, DUffy, P, Lewis, Kromer
c)
Duffy, Knops, Indian
17.
Microbial receptors
a)
Lutheran, Xg, Lewis, Indian
b)
MNSs, DUffy, P, Lewis, Kromer
c)
Duffy, Knops, Indian
18.
Biologic receptors
a)
Lutheran, Xg, Lewis, Indian
b)
MNSs, DUffy, P, Lewis, Kromer
c)
Duffy, Knops, Indian
19.
The Lewis (Le, FUT3) gene is located on...
a)
Chromosome 19
b)
Chromosome 4
c)
Chromosome 22
d)
Chromosome 6
20.
MNS gene is located at
a)
Chromosome 19
b)
Chromosome 4
c)
Chromosome 22
d)
Chromosome 6
21.
P antigen is located on
a)
Chromosome 19
b)
Chromosome 4
c)
Chromosome 22
d)
Chromosome 6
22.
The product of this gene is L-fucosyltransferase which adds L-fucose to the number 4 cation of N-acetylglucosamine of type 1 precursor structures
a)
Lewis gene
b)
I gene
c)
Kell Gene
d)
MNSs gene
23.
What is the product of Lewis gene?
a)
L-fucosyltransferase
b)
N-acetyl-galactosaminyltransferase
c)
D-galactosyltransferase
24.
Which antigen or gene is manufactured by tissue cells and secreted into body fluids and are adsorbed on the red cell membrane?
a)
Lewis gene
b)
I gene
c)
Kell Gene
d)
MNSs gene
25.
Which antigen or gene is needed for the expression of Lea substance, and _ and Se genes are needed to form Leb substance
a)
Lewis gene
b)
I gene
c)
Kell Gene
d)
MNSs gene
26.
Which antigen or gene is Not expressed on cord RBCs, (Le(a-b-) and are often diminished on the mother's RBCs during pregnancy?
a)
Lewis gene
b)
I gene
c)
Kell Gene
d)
MNSs gene
27.
The synthesis of this antigen depends on the interaction of the transferases produced by this antigen and secretor genes
a)
Lewis antigen
b)
I antigen
c)
Kell Antigen
d)
MNSs Antigen
28.
Antibodies are frequently encountered in pregnant women
a)
Lewis antigen
b)
I antigen
c)
Kell Antigen
d)
MNSs Antigen
29.
Neutralized by: saliva, plasma, or commercially prepared substance
a)
Lewis antigen
b)
I antigen
c)
Kell Antigen
d)
MNSs Antigen
30.
Lewis antibodies
a)
Clinically significant
b)
Not clinically significant / clinically insignificant
31.
Which type of Lewis antibodies reacts with Leb and H antigens?
a)
Anti-LebH
b)
Anti-LebL
c)
Anti-Lex
32.
Which type of Lewis antibodies reacts with any Le antigens?
a)
Anti-LebH
b)
Anti-LebL
c)
Anti-Lex
33.
Which type of Lewis antibodies agglutinates all Le (+) individuals, also known as Lewis null phenotype?
a)
Anti-LebH
b)
Anti-LebL
c)
Anti-Lex
34.
Which form of Lewis antigen is always present in the secretion when inherited dominantly?
a)
Lea
b)
Leb
c)
Lex
35.
Which form of Lewis antibodies has 2 forms?
a)
Anti-Lea
b)
Anti-Leb
36.
Which form of Lewis antibodies react with Leb and H antigens?
a)
Anti-LebH
b)
Anti-LebL
37.
Which form of Lewis antibodies react with any Le antigens?
a)
Anti-LebH
b)
Anti-LebL
38.
Which form of Lewis antigen has receptor for Helicobacter pylori
a)
Leb
b)
Lex
39.
Which antibody is commonly encountered in pregnant women?
a)
Lewis AB
b)
Anti-M
c)
Anti-S and anti-s
d)
Anti-N
e)
Anti-U
40.
Which form of Lewis antigen has marker for Reed Sternerg Cells of Hodgkin lymphoma
a)
Leb
b)
Lex
41.
Lewis antibodies are generally.. made by Le(a-b-) individuals
a)
IgM
b)
IgG
42.
Secretion of ABH, lele, sese
a)
None
b)
ABH
c)
Lea
d)
ABH, Lea, Leab
43.
Secretion of ABH, lele, Sese or SeSe
a)
None
b)
ABH
c)
Lea
d)
ABH, Lea, Leab
44.
Secretion of ABH, LeLe or Lele, sese
a)
None
b)
ABH
c)
Lea
d)
ABH, Lea, Leab
45.
Secretion of ABH, LeLe or Lele, SeSe or Sese
a)
None
b)
ABH
c)
Lea
d)
ABH, Lea, Leab
46.
Secretion of ABhh, LeLe or Lele, sese
a)
None
b)
ABH
c)
Lea
d)
ABH, Lea, Leab
47.
Secretion of ABhh, LeLe or Lele, SeSe or Sese
a)
None
b)
ABH
c)
Lea
d)
ABH, Lea, Leab
48.
RBC phenotype of ABH, lele, sese
a)
ABH Le (a-b-)
b)
ABH Le (a+b-)
c)
ABH Le (a-b+)
d)
Le (a+b-)
49.
RBC phenotype of ABH LeLe or Lele, sese
a)
ABH Le (a-b-)
b)
ABH Le (a+b-)
c)
ABH Le (a-b+)
d)
Le (a+b-)
50.
RBC phenotype of ABH LeLe or Lele, SeSe or Sese
a)
ABH Le (a-b-)
b)
ABH Le (a+b-)
c)
ABH Le (a-b+)
d)
Le (a+b-)
51.
RBC phenotype of ABhh LeLe or Lele, sese
a)
ABH Le (a-b-)
b)
ABH Le (a+b-)
c)
ABH Le (a-b+)
d)
Le (a+b-)
52.
RBC phenotype of Abhh LeLe or Lele, SeSe or Sese
a)
ABH Le (a-b-)
b)
ABH Le (a+b-)
c)
ABH Le (a-b+)
d)
Le (a+b-)
53.
Antibodies of ABH, lele, Sese, or sese
a)
Anti-Lea
b)
Anti-Leb
c)
None
d)
Anti-Lea and Anti Leb
54.
Antibodies of ABH LeLe or Lele, sese
a)
Anti-Lea
b)
Anti-Leb
c)
None
d)
Anti-Lea and Anti Leb
55.
Antibodies of ABH LeLe or Lele, SeSe or Sese
a)
Anti-Lea
b)
Anti-Leb
c)
None
d)
Anti-Lea and Anti Leb
56.
Which antibodies of Lewis is the most common?
a)
Anti-Lea
b)
Anti-Leb
c)
None
d)
Anti-Lea and Anti Leb
57.
Antibodies of ABhh LeLe or Lele, sese
a)
Anti-Lea
b)
Anti-Leb
c)
None
d)
Anti-Lea and Anti Leb
58.
Antibodies of Abhh LeLe or Lele, SeSe or Sese
a)
Anti-Lea
b)
Anti-Leb
c)
None
d)
Anti-Lea and Anti Leb
59.
Antibodies of ABH, lele, Sese, or sese
a)
Anti-Lea
b)
Anti-Leb
c)
None
d)
Anti-Lea and Anti Leb
60.
Well developed at birth
a)
MN Antigen
b)
Ss antigen
c)
U antigens
61.
The amino acid residue in position 1 and 5 determine the expression of MN glycophorin A
a)
MN Antigen
b)
Ss antigen
c)
U antigens
62.
located at the outer end of GPA, they are easily destroyed by routine blood bank enzyme
a)
MN Antigen
b)
Ss antigen
c)
U antigens
63.
important markers in paternity testing of infants using specific oligonucleotide probe
a)
MN Antigen
b)
Ss antigen
c)
U antigens
64.
cells may also be En(a-), cells are resistant to invasion by Plasmodium falciparum merozoites
a)
MN Antigen
b)
Ss antigen
c)
U antigens
65.
The amino acid residue in position 29 of glycophorin B determines the expression of
a)
MN Antigen
b)
Ss antigen
c)
U antigens
66.
less easily degraded by enzymes
a)
MN Antigen
b)
Ss antigen
c)
U antigens
67.
stands for universal
a)
MN Antigen
b)
Ss antigen
c)
U antigens
68.
RBCs with S or s antigens also have this antigen
a)
MN Antigen
b)
Ss antigen
c)
U antigens
69.
Found on glycophorin B
a)
MN Antigen
b)
Ss antigen
c)
U antigens
70.
has methionine
a)
S
b)
s
71.
has threonine
a)
S
b)
s
72.
has serine at the amino acid residue in position 1 and 5
a)
M antigen
b)
N antigen
73.
has leucine and glutamic acid at the amino acid residue in position 1 and 5
a)
M antigen
b)
N antigen
74.
Found on glycophorin A (sialic acid rich glycoprotein present on the cell membrane
a)
Lewis gene
b)
MNSs gene
c)
Kell gene
d)
Duffy gene
75.
(M-N-) individuals
a)
En (a-) Phenotype
b)
Mk Phenotype
76.
produces anti-Ena
a)
En (a-) Phenotype
b)
Mk Phenotype
77.
RBCs of these individual typed M-N-S-s-U-En(a-) Wr(a-b-), but they had a normal hematologic picture
a)
En (a-) Phenotype
b)
Mk Phenotype
78.
IgM naturally occurring cold reactive saline agglutinins that do not bind to complement or enzyme-treated cells
a)
Anti-M
b)
Anti-N
c)
Anti-S and Anti-s
d)
Anti-U
79.
Reaction is enhanced by acidification by weak acid (gHAc, weak HCl, acetic anhydride) active at pH 6.0 to 6.5
a)
Anti-M
b)
Anti-N
c)
Anti-S and Anti-s
d)
Anti-U
80.
seen in renal patients who are dialyzed on equipment sterilized with formaldehyde
a)
Anti-M
b)
Anti-N
c)
Anti-S and Anti-s
d)
Anti-U
81.
most are IgG reactive at 37 degree Celsius and AHG phase
a)
Anti-M
b)
Anti-N
c)
Anti-S and Anti-s
d)
Anti-U
82.
May bind complement and have been associated with HDN and HTRs
a)
Anti-M
b)
Anti-N
c)
Anti-S and Anti-s
d)
Anti-U
83.
rare but can be formed in S-s- individuals
a)
Anti-M
b)
Anti-N
c)
Anti-S and Anti-s
d)
Anti-U
84.
IgG, reported to cause severe and fatal HTRs and HDN
a)
Anti-M
b)
Anti-N
c)
Anti-S and Anti-s
d)
Anti-U
85.
What is the phenotype of the Antigen: P1, P, Pk?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
86.
What is the phenotype of the Antigen: P, Pk?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
87.
What is the phenotype of the if there is no antigen?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
88.
What is the phenotype if the Antigen are P1 and Pk?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
89.
What is the phenotype of the Antigen Pk?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
90.
What may be the possible antibodies of P1 phenotype?
a)
None
b)
ANti-P1
c)
Anti-PP1Pk
d)
Anti-P
e)
Anti-P, Anti-P1
91.
What are the possible antibodies of P2 phenotype?
a)
None
b)
Anti-P1
c)
Anti-PP1Pk
d)
Anti-P
e)
Anti-P, Anti-P1
92.
What could be the possible antibodies of p phenotype?
a)
None
b)
Anti-P1
c)
Anti-PP1Pk
d)
Anti-P
e)
Anti-P, Anti-P1
93.
What could be the possible antibodies of P1K?
a)
None
b)
Anti-P1
c)
Anti-PP1Pk
d)
Anti-P
e)
Anti-P, Anti-P1
94.
What could be the possible antibodies of P2k?
a)
None
b)
Anti-P1
c)
Anti-PP1Pk
d)
Anti-P
e)
Anti-P, Anti-P1
95.
What is the phenotype if the antigen is Pk?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
96.
What is the phenotype if the antigen is P1, Pk?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
97.
What is the phenotype if theRe is NO antigen?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
98.
What is the phenotype if the antigen is P, pk?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
99.
What is the phenotype if the antigen is P1, P, Pk?
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
100.
Antibodies: none
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
101.
Antibodies: Anti-P1
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
102.
Antibodies: Anti-PP1Pk
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
103.
Antibodies: Anti-P
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
104.
Antibodies: Anti-P, Anti-P1
a)
P1
b)
P2
c)
p
d)
P1k
e)
P2k
105.
Consists of three antigens which are biochemically related to the CHO chain that makes up the ABH and I antigens
a)
Lewis antigen
b)
MNSs antigen
c)
P antigens
d)
I and I antigens
106.
This antigen are poorly developed at birth
a)
Lewis antigen
b)
MNSs antigen
c)
P antigens
d)
I and I antigens
107.
Which P antigen is already expressed starting 12 weeks of gestation but weakens gestational age; deteriorates rapidly on storage?
a)
p1 Antigens
b)
P1-like antigens
c)
P1-like soluble substances
108.
Which P antigen has been found on plasma and drooping of turtle doves and pigeons?
a)
p1 Antigens
b)
P1-like antigens
c)
P1-like soluble substances
109.
Which P antigen is Seen in hydatid cyst of Echinococcus granulosus, extracts from Lumbricoides terrestris and Ascaris suum?
a)
p1 Antigens
b)
P1-like antigens
c)
P1-like soluble substances
110.
Which P antibodies is Naturally occurring, and include IgM in the sera of P2 individual?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
111.
Which P antibodies is Weak cold reactive saline agglutinins, and optimally reactive at 4 degree Celsius?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
112.
Which P antibodies is Strong and was observed in individuals infected with hydatid disease?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
113.
Which P antibodies Can be neutralized with soluble P1-like substances in hydatid cyst of Echinococcus granulosus?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
114.
Which P antibodies is Associated with fascioliasis, Chlonorcis sinensis, and Opistorchis viverrine infections?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
115.
Which P antibodies is Naturally occurring antibody in the sera of all Pk individuals?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
116.
Which P antibodies has rare Alloanti-P and hemolytic with wide thermal range of reactivity?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
117.
Which P antibodies has specificity found as biphasic IgG autoantibody in patients with paroxysmal cold hemoglobinuria demonstrated by Donath Landsteiner test
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
118.
Which P antibodies is Isolated from some examples of anti-PP1Pk by selective adsorption with P1 cells?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
119.
Which P antibodies is has been reported in the serum of P1 individuals with biliary cirrhosis and autoimmune hemolytic anemia?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
120.
Which P antibodies is predominantly IgM, and sometimes IgG produced by P individuals?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
121.
Which P antibodies Reacts predominantly over a wide thermal range, and binds complement and may demonstrate in vitro hemolysis?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
122.
Which P antibodies is first seen in patient with adenocarcinoma?
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
123.
P antibodies that is aka Anti-Tja
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
124.
Which P antibodies is associated with spontaneous abortions in early pregnancy
a)
Anti-P1
b)
Anti-P
c)
Anti-Pk
d)
Anti-PP1Pk
100 %
